Re: Re: Magnesium and insulin resistance - Gilbert's Syndrome

[Guest guest]

In frequent-dose-chelation Nicola wrote:

Jackie

Gilberts Syndrome is a supposed genetic slowing of the phase 2

glucoronidation function. It primarily affects bilirubin levels, which

are above average in people with GS, and they can look slightly

jaundiced. Doctors are convinced it is genetic and benign, ie no

symptoms.

----------I had the Great Smokies Liver Detox Profile done 2 years ago, and my

Phase 2 Glucoronidation was in range, but was high normal, 1 point from the top.

I think my bilirubin has always been ok, it was in range on recent labwork. So

your bilirubin has been high?--------Jackie

Surprise, surprise, they're wrong.

--------What's new. We have to figure all this stuff out

ourselves!-----Jackie

It can be acquired from exposure to

heavy metals, which is the case with me. Neither of my parents have

Gilberts. It does bring signficant symptoms - insulin resistance being

one of them, fatigue, shakiness, blurred vision, need for frequent

meals, IBS, fat intolerance are all others. Diagnosis is by simple

blood test, which will show bilirubin over the range.

----------I do have some of those symptoms, but my bilirubin is in range.

Which symptoms do you have, and how high is your bilirubin?--------Jackie

Andy alludes to the insulin resistance in Amalgam Illness, where he

talks about the liver functions. He says to increase the

glucoronidation process by taking thryoid hormone and chromium to

reduce insulin resistance.

----------I have been taking chromium picolinate with meals for a long time.

I still am not on any thyroid hormone either. Just HC.--------Jackie

So I think I have always had problems with

glucose tolerance, but taking too much pred has pushed me over the edge

since September.

---------I agree, probably me too, but the high HC this fall is what did me

in.-----Jackie

Hopefully I can get the genie back in the bottle with diet (low GI

anyway and have been for 3 years), supplements, and by reducing the

steroid dosage, which I think is the big one. I have already done this

a bit, and it hasn't been as bad as I thought it would be. So I shall

continue.

---------I am back down to a maintenance dose of 20mg/day of HC, and less a

few times, and I think it is the major factor in this. Because of our

predisposition, we probably have to be more careful than others with the

steroids. I know I learned a lesson!--------Jackie

Are you taking metformin Jackie?

----------I tried it a few weeks ago. I was supposed to take 1 tablet/day for

1 week, and then take 2 tablets/day after that. They warned of side effects

like headaches and nausea and stomach problems, which weren't too bad the first

week, but when I started taking 2 tablets/day, these got much worse. It was

right before Thanksgiving, so I didn't want to have diahrrea then, so I stopped.

I also stopped because I was supposed to have surgery today, and it warned not

to take it then either. I talked to my doctor about it, and he agreed that 2

tablets might be too much for me, and that I should stop it until after the

surgery, and then decide if I want to try it again. also suggested

extended release Metformin. So I may try that. I think I did feel some benefit

from it, probably controlling blood sugar, and I also think I felt less

hungry/ate less when I was taking it, which would be great for me, since I'm

overweight. But now my surgery has been cancelled (my surgeon hurt his back,

what are the odds?) and I don't know when it will be rescheduled, so not sure

when I will be trying it again.--------Jackie

Best

Nicola

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