Re: Re: WHY indomethacin to prevent bone overgrowth????

[Guest guest]

Long term use of NSAIDS has been shown to cause more rapid deterioration of the

bone. Several studies are out, indomethacin is a real culprit. That is why it

is used to prevent heterotopic bon growth around the prosthesis after surgery.

Rock climbin' Jude

LBHR De Smet 09/11/02

Re: WHY indomethacin to prevent bone overgrowth????

Regarding drugs, I've a question/concern. Both my osteopath and

physical therapist recommend using an antiinflammatory such as Vioxx

right now. I am progressing slowly (three months since surgery).

There are two reasons for their recommendation: 1) to access whether

the pain I experience is indeed inflammatory in nature, and not

necessarily emanating out of the hip joint itself; and 2) to give me

more flexibility while performing some of my exercises. I've read

that certain antiinflammatories are frowned upon by certain doctors

post-surgery, although they did give me Vioxx while I was still in

the hospital. Does anyone have experience with Vioxx this far down

the path after surgery?

Thanks!

Lari

> >

> > i notice that those who return from belgium speak of taking

> > indomethecin for the prevention of overgrowth. Can anyone

explain

> > this to me???

> > before i had my hip resurfaced here in the states, i actually

had

> an

> > appointment with de smet...and when i told him that i was taking

> > indomethecin he wrote back in large CAPS...indomethecin is

causing

> > the destruction of your hip...stop taking it.

> >

> > so what's the reasoning behind taking it post surgically???

> anyone

> > know?

> >

> > thanks

> > m

[Guest guest]

Hi Jude,

I know you are doing great as I am. I'm playing lots of tennis and moving

well and fast on the court.

I'm afraid to take anti-inflammatories because of the bone deterioration

issue, but how does aspirin, naprosen, ibuprofen, compare to indomethacin? I do

get aches and pains in the elbow, wrist, and knees (tendons mostly) and wonder

if it's OK to take them a few times a week.

I've heard that untreated inflammation can lead to more severe injury. Is ice

the best and safest of all remedies?

Thanks and take care,

Saeed

bilateral instantaneous w/ Dr. DeSmet, 7-2-02

[Guest guest]

Hi Jude,

I know you are doing great as I am. I'm playing lots of tennis and moving

well and fast on the court.

I'm afraid to take anti-inflammatories because of the bone deterioration

issue, but how does aspirin, naprosen, ibuprofen, compare to indomethacin? I do

get aches and pains in the elbow, wrist, and knees (tendons mostly) and wonder

if it's OK to take them a few times a week.

I've heard that untreated inflammation can lead to more severe injury. Is ice

the best and safest of all remedies?

Thanks and take care,

Saeed

bilateral instantaneous w/ Dr. DeSmet, 7-2-02

[Guest guest]

Vioxx is also a II inhibitor. Studies indicate that they also contribute to

bone deterioration.

Jude

Re: WHY indomethacin to prevent bone overgrowth????

Hi Lari,

Try Bextra. It is a -2 inhibitor NSAID and has less

gastrointestinal side affects than -1 inhibitors like ibuprofen.

It provides great pain relief now and I will use it until I get my

right hip resurfaced in July. It is taken at 20mg/day. Try it you

might like it.

Dr. Mark

> > >

> > > i notice that those who return from belgium speak of taking

> > > indomethecin for the prevention of overgrowth. Can anyone

> explain

> > > this to me???

> > > before i had my hip resurfaced here in the states, i actually

> had

> > an

> > > appointment with de smet...and when i told him that i was

taking

> > > indomethecin he wrote back in large CAPS...indomethecin is

> causing

> > > the destruction of your hip...stop taking it.

> > >

> > > so what's the reasoning behind taking it post surgically???

> > anyone

> > > know?

> > >

> > > thanks

> > > m

[Guest guest]

Vioxx is also a II inhibitor. Studies indicate that they also contribute to

bone deterioration.

Jude

Re: WHY indomethacin to prevent bone overgrowth????

Hi Lari,

Try Bextra. It is a -2 inhibitor NSAID and has less

gastrointestinal side affects than -1 inhibitors like ibuprofen.

It provides great pain relief now and I will use it until I get my

right hip resurfaced in July. It is taken at 20mg/day. Try it you

might like it.

Dr. Mark

> > >

> > > i notice that those who return from belgium speak of taking

> > > indomethecin for the prevention of overgrowth. Can anyone

> explain

> > > this to me???

> > > before i had my hip resurfaced here in the states, i actually

> had

> > an

> > > appointment with de smet...and when i told him that i was

taking

> > > indomethecin he wrote back in large CAPS...indomethecin is

> causing

> > > the destruction of your hip...stop taking it.

> > >

> > > so what's the reasoning behind taking it post surgically???

> > anyone

> > > know?

> > >

> > > thanks

> > > m

[Guest guest]

Vioxx is also a II inhibitor. Studies indicate that they also contribute to

bone deterioration.

Jude

Re: WHY indomethacin to prevent bone overgrowth????

Hi Lari,

Try Bextra. It is a -2 inhibitor NSAID and has less

gastrointestinal side affects than -1 inhibitors like ibuprofen.

It provides great pain relief now and I will use it until I get my

right hip resurfaced in July. It is taken at 20mg/day. Try it you

might like it.

Dr. Mark

> > >

> > > i notice that those who return from belgium speak of taking

> > > indomethecin for the prevention of overgrowth. Can anyone

> explain

> > > this to me???

> > > before i had my hip resurfaced here in the states, i actually

> had

> > an

> > > appointment with de smet...and when i told him that i was

taking

> > > indomethecin he wrote back in large CAPS...indomethecin is

> causing

> > > the destruction of your hip...stop taking it.

> > >

> > > so what's the reasoning behind taking it post surgically???

> > anyone

> > > know?

> > >

> > > thanks

> > > m

[Guest guest]

Anyone know anything about Bextra? Seems to be the new antiinflammatory

being recommended.

Maureen

[Guest guest]

Maureen;

I tried bextra for a month, but it didn't to the trick for me.. I am back to

vioxx, which seems to do a better job for me. But I know people who have a

great results with it & who say that it was easier on their stomach than

vioxx or celebrex.. Good Luck

Glen

-- Re: Re: WHY indomethacin to prevent bone

overgrowth????

Anyone know anything about Bextra? Seems to be the new antiinflammatory

being recommended.

Maureen

[Guest guest]

I had taken Indomethacin off and on for several years prior to a resurf, to

reduce inflammation. It has some side effects, like danger of stomach bleeding,

and I had sort of dizzy spells, so gave it up as a bad job. Dr De Smet

prescribed it for about 3 weeks after surgery, to prevent unwanted bone growth

(ossification?), which surprised me, as I hadn't realized it was used for that

purpose as well as to reduce inflammation of joints. However, it was only for

the 3 weeks, and so it seemed well worth it.

Sharry

Re: Re: WHY indomethacin to prevent bone

overgrowth????

Anyone know anything about Bextra? Seems to be the new antiinflammatory

being recommended.

Maureen

[Guest guest]

I had taken Indomethacin off and on for several years prior to a resurf, to

reduce inflammation. It has some side effects, like danger of stomach bleeding,

and I had sort of dizzy spells, so gave it up as a bad job. Dr De Smet

prescribed it for about 3 weeks after surgery, to prevent unwanted bone growth

(ossification?), which surprised me, as I hadn't realized it was used for that

purpose as well as to reduce inflammation of joints. However, it was only for

the 3 weeks, and so it seemed well worth it.

Sharry

Re: Re: WHY indomethacin to prevent bone

overgrowth????

Anyone know anything about Bextra? Seems to be the new antiinflammatory

being recommended.

Maureen

[Guest guest]

thanks, glen. was wondering if anyone knows whether or not bextra also has

this indomethacin in it, as well.

maureen