TYSABRI......Fw: Peer to Peer Teleconference Series

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Peer to Peer Teleconference Series

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Stay informed about multiple sclerosis and hear personal stories from other people with relapsing MS.

If you are looking to learn more about an MS therapy like TYSABRI, the TYSABRI Hope and Health Teleconference Series may help you make a more informed treatment decision.

Many teleconference programs will be offered in 2011.

When you call, you will hear a healthcare provider discuss treatment information and a panel of TYSABRI patients share their personal experiences. Ask them questions directly, or just listen to the discussion — all in the comfort of your own home.

Registration is easy — at no cost to you.

Sign up for free to learn more!

Simply call 1- ten minutes before the start of each teleconference. When asked for a code, say "Hope and Health Teleconference" - and you'll get connected.

Indication

• TYSABRI is a prescription medicine approved for adult patients with relapsing forms of MS to slow the worsening of physical disability that is common in patients with MS and decrease the number of flare-ups (relapses).

• Because TYSABRI increases the risk of progressive multifocal leukoencephalopathy (PML), a rare brain infection that usually causes death or severe disability, TYSABRI is generally recommended for patients that have not been helped enough by, or cannot tolerate, another treatment for MS.

• TYSABRI does not cure MS and has not been studied for longer than two years or in patients with chronic progressive MS.

Read the Important Safety Information

TYSABRI Hope and Health Teleconference Schedule: 2011

Date/Time (ET)

Topic

July 21, 8PM

Learn more about TYSABRI from TYSABRI patients

August 2, 8PM

My life before / after TYSABRI

August 18, 8PM

Why TYSABRI was right for me

September 6, 8PM

Employment & MS

September 22, 8PM

Am I getting the most from my therapy?

October 4, 8PM

Doctor & Patient Dialogue - What to ask your Doctor about TYSABRI

October 20, 8PM

Caregivers & TYSABRI: A team effort

November 1, 8PM

My life before / after TYSABRI

November 17, 8PM

Enjoying the Holidays While Living with MS

December 6, 8PM

Speaking with your loved ones about TYSABRI

December 22, 8PM

Why my doctor & I still choose TYSABRI

For a complete listing of MS teleconferences and events in your area, visit www.TYSABRI.com

Important Safety Information about TYSABRI

• TYSABRI increases your chance of getting a rare brain infection that usually causes death or severe disability. This infection is called progressive multifocal leukoencephalopathy (PML). PML usually happens in people with weakened immune systems. No one can predict who will get PML. Your chances may be higher if you are also being treated with medicines that weaken your immune system, including other MS treatments. If you use TYSABRI alone to treat your MS, you can still get PML. Your chance of getting PML increases with a longer period of treatment or if you have received

medicines that can weaken your immune system prior to starting TYSABRI. However, PML is a rare event. There is no known treatment, prevention, or cure for PML.

• If you take TYSABRI, it is important to call your doctor right away if you have any new or worsening medical problems (such as a new or sudden change in your thinking, eyesight, balance, or strength or other problems) that have lasted over several days. Tell all of your doctors that you are getting treatment with TYSABRI.

• If you get PML, your doctor will monitor you for certain new or worsening symptoms that can happen suddenly after you get PML. Contact your doctor right away if you think your general health status is getting worse.

• Because of the chance for PML, TYSABRI is generally recommended for patients that have not been helped enough by, or cannot tolerate another treatment for MS. TYSABRI is available only through the TOUCH® Prescribing Program, which is a restricted distribution program. Only prescribers, patients and infusion centers enrolled in the TOUCH Prescribing Program can prescribe, receive, and infuse TYSABRI. Before you take TYSABRI, you and your doctor must enroll in the TOUCH Prescribing Program and agree to the program requirements. Plan to see your doctor 3 months after the first infusion, 6 months after the first infusion, and at least as frequently as 6 months

thereafter.

• TYSABRI does not cure MS and has not been studied longer than two years or in patients with chronic progressive MS. TYSABRI is not approved for use in patients under age 18.

• You should not receive TYSABRI if you have PML or are allergic to TYSABRI or any of its ingredients.

• TYSABRI is not recommended if you have a medical condition that can weaken your immune system, such as HIV infection or AIDS, leukemia or lymphoma, organ transplant, or others, or if you are taking medicines that weaken your immune system.

• Talk with your doctor about all of the medicines you take or have taken. TYSABRI may increase your chance of getting an unusual or serious infection. You should not take TYSABRI if you are pregnant, trying to become pregnant, or nursing.

• TYSABRI may cause liver damage. Symptoms of liver damage include yellowing of the skin and eyes (jaundice), unusual darkening of the urine, nausea, feeling tired or weak, or vomiting. Blood tests can be done to check for liver damage. Call your doctor right away if you experience any symptoms of liver damage.

• Other serious side effects with TYSABRI include allergic reactions (e.g., hives, itching, trouble breathing, chest pain, dizziness, wheezing, chills, rash, nausea, flushing of skin, low blood pressure), including serious allergic reactions (e.g., anaphylaxis) and infections. Serious allergic reactions usually happen within 2 hours of the start of the infusion, but can happen any time after receiving TYSABRI. Tell your doctor or nurse right away if you have any symptom of an allergic reaction. You may need treatment if you are having an allergic reaction. TYSABRI may increase your chance of getting an unusual or serious infection, because it can affect your immune system.

• Common side effects include headache, urinary tract infection, lung infection, pain in your arms and legs, vaginitis, stomach area pain, feeling tired, joint pain, depression, diarrhea, and rash. Tell your doctor about any side effect that bothers you or does not go away.

Please see full Prescribing Information, including Boxed Warning and Patient Medication Guide.

Talk to your doctor about whether TYSABRI is right for you.

To learn more, visit TYSABRI.com or call an MS Support Specialist, Monday to Friday, 8:30 AM to 8:00 PM (EST): 1-.

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