Announcement of Vancomycin clinical trial for adult PSCers

[Guest guest]

For those of you who have been asking about the existence of

a clinical trial using Vancomycin on adult PSCers, here is an announcement I

just received from Massachussetts General Hospital Crohn’s and Colitis

Center.

Massachussetts General Hospital is seeking volunteers, ages

18 years and older, with a known diagnosis of Primary Sclerosing Cholangitis

for a research study to see if a medication (Vancomycin) improves liver disease

symptoms, such as itchiness and fatigue and liver function tests.

Participants should not be pregnant or breastfeeding,

should not have any known allergy to Vancomycin and should not have normal

liver function tests.

Participation may last up to one year. Subjects will

take Vancomycin daily for 52 weeks and have follow up visits every 6

weeks. Laboratory tests will be done at screening and every 12

weeks. A liver biopsy and MRCP (MRI of the liver) will be done at the

beginning and at the end of the study. A flexible sigmoidoscopy will be

done at the beginning of the study and at week 12.

For more information, please contact at (617)

724-3238. mentioned that participants should live within driving

distance of Boston.

Ricky

PSC 2003