Question on lab results

[Guest guest]

Hi Everyone,

My gastro ordered some labwork last week and I went and picked up a

copy of the results today. I was wondering if anyone could answer a

question about the glomerular filtration rate. I know it has to do

with kidney function from a quick internet search. Is it one of those

lab results that tend to vary with PSC? My report says mine is 45

mL/min/1.73 squared. There is a box on the report that says the

population mean for my age is 107 mL/min/1.73 and that less than 60

mL/min/1.73 square meters is indicative of chronic kidney disease.

If this is one of those lab results that can vary with PSC then I'm

happy to ignore it. If its something to investigate then I guess I'll

have to make sure my primary care dr got the labwork from the gastro

and make an appt. Any advice would be appreciated.

Thanks,

Darcy

PSC 2007

[Guest guest]

> ... I was wondering if anyone could answer a

> question about the glomerular filtration rate. I know it has to do

> with kidney function from a quick internet search. Is it one of those

> lab results that tend to vary with PSC? My report says mine is 45

> mL/min/1.73 squared. ... less than 60

> mL/min/1.73 square meters is indicative of chronic kidney disease.

PSC shouldn't have much of an effect on kidney function until you

reach end stage liver disease. Then, hepatorenal syndrome (HRS), an

acute renal failure that occurs in the setting of cirrhosis or

fulminant liver failure, becomes a risk - and is why creatinine level

is a component of the MELD score. I would definitely check with your

doctor to see if there is anything you can do to help your kidney

function. There may be medicines you are taking that could be switched

to ones that are easier on the kidneys. My nephrologists advised me to

switch from prograf to sirolimus and to add vitamin D supplements, but

both low GFR and high blood pressure are the reasons I consult them.

Tim R

[Guest guest]

> ... I was wondering if anyone could answer a

> question about the glomerular filtration rate. I know it has to do

> with kidney function from a quick internet search. Is it one of those

> lab results that tend to vary with PSC? My report says mine is 45

> mL/min/1.73 squared. ... less than 60

> mL/min/1.73 square meters is indicative of chronic kidney disease.

PSC shouldn't have much of an effect on kidney function until you

reach end stage liver disease. Then, hepatorenal syndrome (HRS), an

acute renal failure that occurs in the setting of cirrhosis or

fulminant liver failure, becomes a risk - and is why creatinine level

is a component of the MELD score. I would definitely check with your

doctor to see if there is anything you can do to help your kidney

function. There may be medicines you are taking that could be switched

to ones that are easier on the kidneys. My nephrologists advised me to

switch from prograf to sirolimus and to add vitamin D supplements, but

both low GFR and high blood pressure are the reasons I consult them.

Tim R

[Guest guest]

Thanks to everyone for your replies!!

I don't have UC and haven't had any medication changes other than adding antibiotics everyday but that was done after the labs were drawn. My creatinine level is also elevated along with the low GFR. I'm guessing that I should probably call my family dr. I'm just dragging my feet because I wanted to be doctor-free for the rest of 2008.

Thanks again,

Darcy