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Young Blood Rejuvenates Old Muscles

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Many of us have low ferritin. There seems to be no real reason that with all the

iron we take that the red cells are still not doing well. I found this article

Now it is not exactly the same thing as you will see. but maybe there is a line

to think along. Any comments?

Young Blood Rejuvenates Old Muscles

Feb 17 2005

THURSDAY, Feb. 17 (HealthDay News) -- Young blood can help revive damaged older

muscles, according to a study that found the blood of aged mice somehow hinders

muscle's ability to repair itself.

In the study, researchers from Stanford University focused on specialized cells

called satellite cells, which are stem cells sprinkled throughout muscle tissue.

These satellite cells are normally dormant but spring into action whenever

muscles in young mice are damaged. However, in older mice, satellite cells don't

appear to respond to muscle damage.

The Stanford researchers hooked up a group of older mice with a group of younger

mice in a way that allowed both groups to share the same blood supply. The

researchers then induced muscle damage in the older mice. When these older mice

were hooked up to a blood supply from older mice, their muscles healed slowly.

But when the older mice received blood from younger mice, their muscles healed

much more quickly.

The researchers also studied the livers of older mice who received blood from

younger mice. They found that cells that help liver tissue regenerate were more

active in older mice when they received younger blood.

The study appears in the Feb. 17 issue of Nature.

The findings indicate that something in younger blood revives regenerative cells

in muscle and the liver, the researchers said.

Lead researcher Dr. Rando, associate professor of neurology and

neurological services, suggested that age-related problems in chemicals

surrounding the satellite cells, not the cells themselves, might be at fault.

" We need to consider the possibility that the niche in which stem cells sit is

as important in terms of stem cell aging as the cells themselves, " he said in a

prepared statement.

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