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Re: New lab numbers

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Rick,

My labs have been around those numbers or higher for a year and a half

since being diagnosed. So I myself would not be overly concerned about

them. The main reason I am listed is that I have cirrhosis.

PSC5/07 Listed

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Rick,

These numbers are actually fairly normal for PSC patients. For PSC

you would expect an elevated Alk Phos. due to involvement of the bile

ducts. AST is also elevated but not in a range that would raise any

concern.

As for Bili, a Total Bili of 1.0 is great. Direct bili is only

slightly elevated. If you were experiencing symptoms of jaundice

these numbers would be significantly higher.

Albumin is also in great shape. I would not be concerned with that

until you see a consistant drop below 3.0.

Here are some of my recent labs to give you some context. I am Stage

IV PSC, was diagnosed in 2001 and I am not yet even listed and

continuing to live a full and normal life. These numbers show you

have much fluctuation you can see in these numbers.

24-Jul

4.5 ALB

7.1 Tot B

5.2 Dir B

387 Alk

129 AST

152 ALT

30-Sep

4.4 ALB

3.6 Tot B

3.3 Dir B

316 Alk

116 Ast

109 Alt

in Seattle

>

> I've posted recently about some fears of CCA causing my recent

> increase in bilirubin. My GI at one point was very concerned about

> CCA as a result of my labwork, but now is not. We're not even

going

> to go through with an ERCP until it is scheduled as part of

> my " routine " in April of 2009. My question to all of you is

whether

> you would be conerned about lab results like these:

>

>

> Alk Phos: 327

> AST: 118

> Total Bili: 1.0

> Direct bili: .4 (this is high - normal is .3)

> Albumin: 4.5

>

>

> The above numbers are up from where they were earlier this year,

but

> they are down slightly from where they were in October.....

>

> I'm mostly concerned about the direct bilirubin and AST because

both

> are about double where they were earlier this year. Should I be

> pressing to have an ERCP or MRCP done now rather than waiting until

> April?

>

> Thanks for any help here!

>

> Rick

>

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Rick,

These numbers are actually fairly normal for PSC patients. For PSC

you would expect an elevated Alk Phos. due to involvement of the bile

ducts. AST is also elevated but not in a range that would raise any

concern.

As for Bili, a Total Bili of 1.0 is great. Direct bili is only

slightly elevated. If you were experiencing symptoms of jaundice

these numbers would be significantly higher.

Albumin is also in great shape. I would not be concerned with that

until you see a consistant drop below 3.0.

Here are some of my recent labs to give you some context. I am Stage

IV PSC, was diagnosed in 2001 and I am not yet even listed and

continuing to live a full and normal life. These numbers show you

have much fluctuation you can see in these numbers.

24-Jul

4.5 ALB

7.1 Tot B

5.2 Dir B

387 Alk

129 AST

152 ALT

30-Sep

4.4 ALB

3.6 Tot B

3.3 Dir B

316 Alk

116 Ast

109 Alt

in Seattle

>

> I've posted recently about some fears of CCA causing my recent

> increase in bilirubin. My GI at one point was very concerned about

> CCA as a result of my labwork, but now is not. We're not even

going

> to go through with an ERCP until it is scheduled as part of

> my " routine " in April of 2009. My question to all of you is

whether

> you would be conerned about lab results like these:

>

>

> Alk Phos: 327

> AST: 118

> Total Bili: 1.0

> Direct bili: .4 (this is high - normal is .3)

> Albumin: 4.5

>

>

> The above numbers are up from where they were earlier this year,

but

> they are down slightly from where they were in October.....

>

> I'm mostly concerned about the direct bilirubin and AST because

both

> are about double where they were earlier this year. Should I be

> pressing to have an ERCP or MRCP done now rather than waiting until

> April?

>

> Thanks for any help here!

>

> Rick

>

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Rick,

These numbers are actually fairly normal for PSC patients. For PSC

you would expect an elevated Alk Phos. due to involvement of the bile

ducts. AST is also elevated but not in a range that would raise any

concern.

As for Bili, a Total Bili of 1.0 is great. Direct bili is only

slightly elevated. If you were experiencing symptoms of jaundice

these numbers would be significantly higher.

Albumin is also in great shape. I would not be concerned with that

until you see a consistant drop below 3.0.

Here are some of my recent labs to give you some context. I am Stage

IV PSC, was diagnosed in 2001 and I am not yet even listed and

continuing to live a full and normal life. These numbers show you

have much fluctuation you can see in these numbers.

24-Jul

4.5 ALB

7.1 Tot B

5.2 Dir B

387 Alk

129 AST

152 ALT

30-Sep

4.4 ALB

3.6 Tot B

3.3 Dir B

316 Alk

116 Ast

109 Alt

in Seattle

>

> I've posted recently about some fears of CCA causing my recent

> increase in bilirubin. My GI at one point was very concerned about

> CCA as a result of my labwork, but now is not. We're not even

going

> to go through with an ERCP until it is scheduled as part of

> my " routine " in April of 2009. My question to all of you is

whether

> you would be conerned about lab results like these:

>

>

> Alk Phos: 327

> AST: 118

> Total Bili: 1.0

> Direct bili: .4 (this is high - normal is .3)

> Albumin: 4.5

>

>

> The above numbers are up from where they were earlier this year,

but

> they are down slightly from where they were in October.....

>

> I'm mostly concerned about the direct bilirubin and AST because

both

> are about double where they were earlier this year. Should I be

> pressing to have an ERCP or MRCP done now rather than waiting until

> April?

>

> Thanks for any help here!

>

> Rick

>

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,

Thank you for your reply. The lab results in context are very

helpful. It's great that you're still living a full life at stage

IV. Thanks again for sharing!

Rick

> >

> > I've posted recently about some fears of CCA causing my recent

> > increase in bilirubin. My GI at one point was very concerned

about

> > CCA as a result of my labwork, but now is not. We're not even

> going

> > to go through with an ERCP until it is scheduled as part of

> > my " routine " in April of 2009. My question to all of you is

> whether

> > you would be conerned about lab results like these:

> >

> >

> > Alk Phos: 327

> > AST: 118

> > Total Bili: 1.0

> > Direct bili: .4 (this is high - normal is .3)

> > Albumin: 4.5

> >

> >

> > The above numbers are up from where they were earlier this year,

> but

> > they are down slightly from where they were in October.....

> >

> > I'm mostly concerned about the direct bilirubin and AST because

> both

> > are about double where they were earlier this year. Should I be

> > pressing to have an ERCP or MRCP done now rather than waiting

until

> > April?

> >

> > Thanks for any help here!

> >

> > Rick

> >

>

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