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Re: reading issues/seeing letters backwards

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Hi Stevie

Eyes must be the topic of the day as I was going to post a

question.

Sorry I am unable to help with your sons problem, I do hope Omega 3

helps.

I am old enought to be your son's grandmother and at the moment I am

loosing the sight in one eye, I have had visual field tests which

show a rapid deterioration, a test to see the blood flow to my

eye...appears to be in normal range, an MRI to see if there is a

problem with my brain.... but nothing. I am on drops to lower the

pressure in my eye...even though it is normal and await while the

specialist consults with others for any clues as to the problem.

My question is that even though I do not have IBD could this be a

possible cause, the specislist seems to think that IBD should effect

both eyes not just the one, there are no problems with the other eye.

>

> Just worried it may not be Dyslexia and soemthing else since it

came out

> of no where at 11 yrs old with no prior reading problems..

>

>

> thanks,

>

> Stevie OStos

>

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Hi Stevie

Eyes must be the topic of the day as I was going to post a

question.

Sorry I am unable to help with your sons problem, I do hope Omega 3

helps.

I am old enought to be your son's grandmother and at the moment I am

loosing the sight in one eye, I have had visual field tests which

show a rapid deterioration, a test to see the blood flow to my

eye...appears to be in normal range, an MRI to see if there is a

problem with my brain.... but nothing. I am on drops to lower the

pressure in my eye...even though it is normal and await while the

specialist consults with others for any clues as to the problem.

My question is that even though I do not have IBD could this be a

possible cause, the specislist seems to think that IBD should effect

both eyes not just the one, there are no problems with the other eye.

>

> Just worried it may not be Dyslexia and soemthing else since it

came out

> of no where at 11 yrs old with no prior reading problems..

>

>

> thanks,

>

> Stevie OStos

>

Link to comment
Share on other sites

Hi Stevie

Eyes must be the topic of the day as I was going to post a

question.

Sorry I am unable to help with your sons problem, I do hope Omega 3

helps.

I am old enought to be your son's grandmother and at the moment I am

loosing the sight in one eye, I have had visual field tests which

show a rapid deterioration, a test to see the blood flow to my

eye...appears to be in normal range, an MRI to see if there is a

problem with my brain.... but nothing. I am on drops to lower the

pressure in my eye...even though it is normal and await while the

specialist consults with others for any clues as to the problem.

My question is that even though I do not have IBD could this be a

possible cause, the specislist seems to think that IBD should effect

both eyes not just the one, there are no problems with the other eye.

>

> Just worried it may not be Dyslexia and soemthing else since it

came out

> of no where at 11 yrs old with no prior reading problems..

>

>

> thanks,

>

> Stevie OStos

>

Link to comment
Share on other sites

Dear Stevie;

My mother-in-law had a stroke and brain hemorrage about a month and a

half ago, and the only immediate symptom was loss of ability to read

(she was able to speak and write normally). This turned out to

be " alexia without agraphia " ... the patient can write but cannot

read (even what they have just written):

http://en.wikipedia.org/wiki/ia_without_agraphia

I would doubt that your 11 year-old could have had a stroke! But this

does point out that reading ability can be specifically affected by

changes in certain regions of the brain. It would be worth talking

with a neurologist if you are concerned about Tyler's sudden change

in reading ability.

Best regards,

Dave

(father of (23); PSC 07/03; UC 08/03)

> Just worried it may not be Dyslexia and soemthing else since it

came out of no where at 11 yrs old with no prior reading problems..

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Thanks , I wil take your advise and contact a Neurologist because of the sudden onset. However, I still wonder if it could be a side effect of the Remicade infusions, he has been gettign them for over a year.

At Your Service,

Stevie Lynn Gedgaudas-Ostos

Customer Care Manager-

" "

" "

Sent by:

12/17/2008 09:32 PM

Please respond to

To

cc

Subject

Re: reading issues/seeing letters backwards

Dear Stevie;

My mother-in-law had a stroke and brain hemorrage about a month and a

half ago, and the only immediate symptom was loss of ability to read

(she was able to speak and write normally). This turned out to

be " alexia without agraphia " ... the patient can write but cannot

read (even what they have just written):

http://en.wikipedia.org/wiki/ia_without_agraphia

I would doubt that your 11 year-old could have had a stroke! But this

does point out that reading ability can be specifically affected by

changes in certain regions of the brain. It would be worth talking

with a neurologist if you are concerned about Tyler's sudden change

in reading ability.

Best regards,

Dave

(father of (23); PSC 07/03; UC 08/03)

> Just worried it may not be Dyslexia and soemthing else since it

came out of no where at 11 yrs old with no prior reading problems..

Link to comment
Share on other sites

Thanks , I wil take your advise and contact a Neurologist because of the sudden onset. However, I still wonder if it could be a side effect of the Remicade infusions, he has been gettign them for over a year.

At Your Service,

Stevie Lynn Gedgaudas-Ostos

Customer Care Manager-

" "

" "

Sent by:

12/17/2008 09:32 PM

Please respond to

To

cc

Subject

Re: reading issues/seeing letters backwards

Dear Stevie;

My mother-in-law had a stroke and brain hemorrage about a month and a

half ago, and the only immediate symptom was loss of ability to read

(she was able to speak and write normally). This turned out to

be " alexia without agraphia " ... the patient can write but cannot

read (even what they have just written):

http://en.wikipedia.org/wiki/ia_without_agraphia

I would doubt that your 11 year-old could have had a stroke! But this

does point out that reading ability can be specifically affected by

changes in certain regions of the brain. It would be worth talking

with a neurologist if you are concerned about Tyler's sudden change

in reading ability.

Best regards,

Dave

(father of (23); PSC 07/03; UC 08/03)

> Just worried it may not be Dyslexia and soemthing else since it

came out of no where at 11 yrs old with no prior reading problems..

Link to comment
Share on other sites

Thanks , I wil take your advise and contact a Neurologist because of the sudden onset. However, I still wonder if it could be a side effect of the Remicade infusions, he has been gettign them for over a year.

At Your Service,

Stevie Lynn Gedgaudas-Ostos

Customer Care Manager-

" "

" "

Sent by:

12/17/2008 09:32 PM

Please respond to

To

cc

Subject

Re: reading issues/seeing letters backwards

Dear Stevie;

My mother-in-law had a stroke and brain hemorrage about a month and a

half ago, and the only immediate symptom was loss of ability to read

(she was able to speak and write normally). This turned out to

be " alexia without agraphia " ... the patient can write but cannot

read (even what they have just written):

http://en.wikipedia.org/wiki/ia_without_agraphia

I would doubt that your 11 year-old could have had a stroke! But this

does point out that reading ability can be specifically affected by

changes in certain regions of the brain. It would be worth talking

with a neurologist if you are concerned about Tyler's sudden change

in reading ability.

Best regards,

Dave

(father of (23); PSC 07/03; UC 08/03)

> Just worried it may not be Dyslexia and soemthing else since it

came out of no where at 11 yrs old with no prior reading problems..

Link to comment
Share on other sites

Dear Stevie;

As I am sure that you are aware, there are reports of neurotoxicity

associated with biological agents such as inflximab (remicade). Some

cases of demyelination have been reported:

Aliment Pharmacol Ther. 2008 Nov 4. [Epub ahead of print]

The safety profile of anti-TNF therapy in inflammatory bowel disease

in clinical practice: analysis of 620 patient-years follow-up.

Lees CW, Ali A, AI, Ho GT, Forsythe RO, Marquez L, Cochrane

CJ, Aitken S, Fennell J, P, Shand AG, Penman ID, Palmer KR,

DC, Arnott ID, Satsangi J

Gastrointestinal Unit, Western General Hospital, Crewe Road,

Edinburgh, EH4 2XU, U.K.

Background and Aims. Anti-TNF agents are now widely used in Crohn's

disease (CD), and in ulcerative colitis (UC). We reviewed the safety

profile of these agents in all patients treated with infliximab in

Edinburgh from 1999-2007. Methods. Complete data were available on

202/207 patients comprising 157 CD, 42 UC, and 3 coeliac disease.

Median follow-up was 2.4 years (1.0-4.9) with a total of 620 patient-

years follow-up. 19.1% of CD patients were subsequently treated with

adalimumab. Results. Seven deaths (3.3%) occurred in follow-up - only

one death was <1 year post-infliximab (at day 72, from lung cancer).

6 malignancies (3 haematological, 3 bronchogenic) and 6 cases of

suspected demyelination (3 with confirmed neurological disease) were

reported. In the 90 days following infliximab, 95 adverse events (36

serious) occurred in 58/202 (28.7%) patients. 42/202 (20.8%) had an

infectious event (22 serious). 27/202 (13.4%) of patients had an

infusion reaction - 19 acute (4 serious); 8 delayed (3 serious).

Conclusions. Serious infections, malignancies and neurological

disease complicate anti-TNF use in clinical practice. Although

evidence for causality is unclear, potential mechanisms and

predisposing factors need be explored. In individual patients, the

risk/benefit analysis needs to be carefully assessed and discussed

prior to commencement of therapy. PMID: 19006536.

What I do not know is ... what are the early symptoms of

neurotoxicity and/or demyelination?... and this is where a

neurologist would be able to help you if you are concerned about such

side effects.

Best regards,

Dave

(father of (23); PSC 07/03; UC 08/03)

> Thanks , I wil take your advise and contact a Neurologist

because of the sudden onset. However, I still wonder if it could be a

side effect of the Remicade infusions, he has been gettign them for

over a year.

Link to comment
Share on other sites

Dear Stevie;

As I am sure that you are aware, there are reports of neurotoxicity

associated with biological agents such as inflximab (remicade). Some

cases of demyelination have been reported:

Aliment Pharmacol Ther. 2008 Nov 4. [Epub ahead of print]

The safety profile of anti-TNF therapy in inflammatory bowel disease

in clinical practice: analysis of 620 patient-years follow-up.

Lees CW, Ali A, AI, Ho GT, Forsythe RO, Marquez L, Cochrane

CJ, Aitken S, Fennell J, P, Shand AG, Penman ID, Palmer KR,

DC, Arnott ID, Satsangi J

Gastrointestinal Unit, Western General Hospital, Crewe Road,

Edinburgh, EH4 2XU, U.K.

Background and Aims. Anti-TNF agents are now widely used in Crohn's

disease (CD), and in ulcerative colitis (UC). We reviewed the safety

profile of these agents in all patients treated with infliximab in

Edinburgh from 1999-2007. Methods. Complete data were available on

202/207 patients comprising 157 CD, 42 UC, and 3 coeliac disease.

Median follow-up was 2.4 years (1.0-4.9) with a total of 620 patient-

years follow-up. 19.1% of CD patients were subsequently treated with

adalimumab. Results. Seven deaths (3.3%) occurred in follow-up - only

one death was <1 year post-infliximab (at day 72, from lung cancer).

6 malignancies (3 haematological, 3 bronchogenic) and 6 cases of

suspected demyelination (3 with confirmed neurological disease) were

reported. In the 90 days following infliximab, 95 adverse events (36

serious) occurred in 58/202 (28.7%) patients. 42/202 (20.8%) had an

infectious event (22 serious). 27/202 (13.4%) of patients had an

infusion reaction - 19 acute (4 serious); 8 delayed (3 serious).

Conclusions. Serious infections, malignancies and neurological

disease complicate anti-TNF use in clinical practice. Although

evidence for causality is unclear, potential mechanisms and

predisposing factors need be explored. In individual patients, the

risk/benefit analysis needs to be carefully assessed and discussed

prior to commencement of therapy. PMID: 19006536.

What I do not know is ... what are the early symptoms of

neurotoxicity and/or demyelination?... and this is where a

neurologist would be able to help you if you are concerned about such

side effects.

Best regards,

Dave

(father of (23); PSC 07/03; UC 08/03)

> Thanks , I wil take your advise and contact a Neurologist

because of the sudden onset. However, I still wonder if it could be a

side effect of the Remicade infusions, he has been gettign them for

over a year.

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