Guest guest Posted December 17, 2008 Report Share Posted December 17, 2008 Hi Stevie Eyes must be the topic of the day as I was going to post a question. Sorry I am unable to help with your sons problem, I do hope Omega 3 helps. I am old enought to be your son's grandmother and at the moment I am loosing the sight in one eye, I have had visual field tests which show a rapid deterioration, a test to see the blood flow to my eye...appears to be in normal range, an MRI to see if there is a problem with my brain.... but nothing. I am on drops to lower the pressure in my eye...even though it is normal and await while the specialist consults with others for any clues as to the problem. My question is that even though I do not have IBD could this be a possible cause, the specislist seems to think that IBD should effect both eyes not just the one, there are no problems with the other eye. > > Just worried it may not be Dyslexia and soemthing else since it came out > of no where at 11 yrs old with no prior reading problems.. > > > thanks, > > Stevie OStos > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 17, 2008 Report Share Posted December 17, 2008 Hi Stevie Eyes must be the topic of the day as I was going to post a question. Sorry I am unable to help with your sons problem, I do hope Omega 3 helps. I am old enought to be your son's grandmother and at the moment I am loosing the sight in one eye, I have had visual field tests which show a rapid deterioration, a test to see the blood flow to my eye...appears to be in normal range, an MRI to see if there is a problem with my brain.... but nothing. I am on drops to lower the pressure in my eye...even though it is normal and await while the specialist consults with others for any clues as to the problem. My question is that even though I do not have IBD could this be a possible cause, the specislist seems to think that IBD should effect both eyes not just the one, there are no problems with the other eye. > > Just worried it may not be Dyslexia and soemthing else since it came out > of no where at 11 yrs old with no prior reading problems.. > > > thanks, > > Stevie OStos > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 17, 2008 Report Share Posted December 17, 2008 Hi Stevie Eyes must be the topic of the day as I was going to post a question. Sorry I am unable to help with your sons problem, I do hope Omega 3 helps. I am old enought to be your son's grandmother and at the moment I am loosing the sight in one eye, I have had visual field tests which show a rapid deterioration, a test to see the blood flow to my eye...appears to be in normal range, an MRI to see if there is a problem with my brain.... but nothing. I am on drops to lower the pressure in my eye...even though it is normal and await while the specialist consults with others for any clues as to the problem. My question is that even though I do not have IBD could this be a possible cause, the specislist seems to think that IBD should effect both eyes not just the one, there are no problems with the other eye. > > Just worried it may not be Dyslexia and soemthing else since it came out > of no where at 11 yrs old with no prior reading problems.. > > > thanks, > > Stevie OStos > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 17, 2008 Report Share Posted December 17, 2008 Dear Stevie; My mother-in-law had a stroke and brain hemorrage about a month and a half ago, and the only immediate symptom was loss of ability to read (she was able to speak and write normally). This turned out to be " alexia without agraphia " ... the patient can write but cannot read (even what they have just written): http://en.wikipedia.org/wiki/ia_without_agraphia I would doubt that your 11 year-old could have had a stroke! But this does point out that reading ability can be specifically affected by changes in certain regions of the brain. It would be worth talking with a neurologist if you are concerned about Tyler's sudden change in reading ability. Best regards, Dave (father of (23); PSC 07/03; UC 08/03) > Just worried it may not be Dyslexia and soemthing else since it came out of no where at 11 yrs old with no prior reading problems.. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 19, 2008 Report Share Posted December 19, 2008 Thanks , I wil take your advise and contact a Neurologist because of the sudden onset. However, I still wonder if it could be a side effect of the Remicade infusions, he has been gettign them for over a year. At Your Service, Stevie Lynn Gedgaudas-Ostos Customer Care Manager- " " " " Sent by: 12/17/2008 09:32 PM Please respond to To cc Subject Re: reading issues/seeing letters backwards Dear Stevie; My mother-in-law had a stroke and brain hemorrage about a month and a half ago, and the only immediate symptom was loss of ability to read (she was able to speak and write normally). This turned out to be " alexia without agraphia " ... the patient can write but cannot read (even what they have just written): http://en.wikipedia.org/wiki/ia_without_agraphia I would doubt that your 11 year-old could have had a stroke! But this does point out that reading ability can be specifically affected by changes in certain regions of the brain. It would be worth talking with a neurologist if you are concerned about Tyler's sudden change in reading ability. Best regards, Dave (father of (23); PSC 07/03; UC 08/03) > Just worried it may not be Dyslexia and soemthing else since it came out of no where at 11 yrs old with no prior reading problems.. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 19, 2008 Report Share Posted December 19, 2008 Thanks , I wil take your advise and contact a Neurologist because of the sudden onset. However, I still wonder if it could be a side effect of the Remicade infusions, he has been gettign them for over a year. At Your Service, Stevie Lynn Gedgaudas-Ostos Customer Care Manager- " " " " Sent by: 12/17/2008 09:32 PM Please respond to To cc Subject Re: reading issues/seeing letters backwards Dear Stevie; My mother-in-law had a stroke and brain hemorrage about a month and a half ago, and the only immediate symptom was loss of ability to read (she was able to speak and write normally). This turned out to be " alexia without agraphia " ... the patient can write but cannot read (even what they have just written): http://en.wikipedia.org/wiki/ia_without_agraphia I would doubt that your 11 year-old could have had a stroke! But this does point out that reading ability can be specifically affected by changes in certain regions of the brain. It would be worth talking with a neurologist if you are concerned about Tyler's sudden change in reading ability. Best regards, Dave (father of (23); PSC 07/03; UC 08/03) > Just worried it may not be Dyslexia and soemthing else since it came out of no where at 11 yrs old with no prior reading problems.. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 19, 2008 Report Share Posted December 19, 2008 Thanks , I wil take your advise and contact a Neurologist because of the sudden onset. However, I still wonder if it could be a side effect of the Remicade infusions, he has been gettign them for over a year. At Your Service, Stevie Lynn Gedgaudas-Ostos Customer Care Manager- " " " " Sent by: 12/17/2008 09:32 PM Please respond to To cc Subject Re: reading issues/seeing letters backwards Dear Stevie; My mother-in-law had a stroke and brain hemorrage about a month and a half ago, and the only immediate symptom was loss of ability to read (she was able to speak and write normally). This turned out to be " alexia without agraphia " ... the patient can write but cannot read (even what they have just written): http://en.wikipedia.org/wiki/ia_without_agraphia I would doubt that your 11 year-old could have had a stroke! But this does point out that reading ability can be specifically affected by changes in certain regions of the brain. It would be worth talking with a neurologist if you are concerned about Tyler's sudden change in reading ability. Best regards, Dave (father of (23); PSC 07/03; UC 08/03) > Just worried it may not be Dyslexia and soemthing else since it came out of no where at 11 yrs old with no prior reading problems.. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 20, 2008 Report Share Posted December 20, 2008 Dear Stevie; As I am sure that you are aware, there are reports of neurotoxicity associated with biological agents such as inflximab (remicade). Some cases of demyelination have been reported: Aliment Pharmacol Ther. 2008 Nov 4. [Epub ahead of print] The safety profile of anti-TNF therapy in inflammatory bowel disease in clinical practice: analysis of 620 patient-years follow-up. Lees CW, Ali A, AI, Ho GT, Forsythe RO, Marquez L, Cochrane CJ, Aitken S, Fennell J, P, Shand AG, Penman ID, Palmer KR, DC, Arnott ID, Satsangi J Gastrointestinal Unit, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, U.K. Background and Aims. Anti-TNF agents are now widely used in Crohn's disease (CD), and in ulcerative colitis (UC). We reviewed the safety profile of these agents in all patients treated with infliximab in Edinburgh from 1999-2007. Methods. Complete data were available on 202/207 patients comprising 157 CD, 42 UC, and 3 coeliac disease. Median follow-up was 2.4 years (1.0-4.9) with a total of 620 patient- years follow-up. 19.1% of CD patients were subsequently treated with adalimumab. Results. Seven deaths (3.3%) occurred in follow-up - only one death was <1 year post-infliximab (at day 72, from lung cancer). 6 malignancies (3 haematological, 3 bronchogenic) and 6 cases of suspected demyelination (3 with confirmed neurological disease) were reported. In the 90 days following infliximab, 95 adverse events (36 serious) occurred in 58/202 (28.7%) patients. 42/202 (20.8%) had an infectious event (22 serious). 27/202 (13.4%) of patients had an infusion reaction - 19 acute (4 serious); 8 delayed (3 serious). Conclusions. Serious infections, malignancies and neurological disease complicate anti-TNF use in clinical practice. Although evidence for causality is unclear, potential mechanisms and predisposing factors need be explored. In individual patients, the risk/benefit analysis needs to be carefully assessed and discussed prior to commencement of therapy. PMID: 19006536. What I do not know is ... what are the early symptoms of neurotoxicity and/or demyelination?... and this is where a neurologist would be able to help you if you are concerned about such side effects. Best regards, Dave (father of (23); PSC 07/03; UC 08/03) > Thanks , I wil take your advise and contact a Neurologist because of the sudden onset. However, I still wonder if it could be a side effect of the Remicade infusions, he has been gettign them for over a year. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 20, 2008 Report Share Posted December 20, 2008 Dear Stevie; As I am sure that you are aware, there are reports of neurotoxicity associated with biological agents such as inflximab (remicade). Some cases of demyelination have been reported: Aliment Pharmacol Ther. 2008 Nov 4. [Epub ahead of print] The safety profile of anti-TNF therapy in inflammatory bowel disease in clinical practice: analysis of 620 patient-years follow-up. Lees CW, Ali A, AI, Ho GT, Forsythe RO, Marquez L, Cochrane CJ, Aitken S, Fennell J, P, Shand AG, Penman ID, Palmer KR, DC, Arnott ID, Satsangi J Gastrointestinal Unit, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, U.K. Background and Aims. Anti-TNF agents are now widely used in Crohn's disease (CD), and in ulcerative colitis (UC). We reviewed the safety profile of these agents in all patients treated with infliximab in Edinburgh from 1999-2007. Methods. Complete data were available on 202/207 patients comprising 157 CD, 42 UC, and 3 coeliac disease. Median follow-up was 2.4 years (1.0-4.9) with a total of 620 patient- years follow-up. 19.1% of CD patients were subsequently treated with adalimumab. Results. Seven deaths (3.3%) occurred in follow-up - only one death was <1 year post-infliximab (at day 72, from lung cancer). 6 malignancies (3 haematological, 3 bronchogenic) and 6 cases of suspected demyelination (3 with confirmed neurological disease) were reported. In the 90 days following infliximab, 95 adverse events (36 serious) occurred in 58/202 (28.7%) patients. 42/202 (20.8%) had an infectious event (22 serious). 27/202 (13.4%) of patients had an infusion reaction - 19 acute (4 serious); 8 delayed (3 serious). Conclusions. Serious infections, malignancies and neurological disease complicate anti-TNF use in clinical practice. Although evidence for causality is unclear, potential mechanisms and predisposing factors need be explored. In individual patients, the risk/benefit analysis needs to be carefully assessed and discussed prior to commencement of therapy. PMID: 19006536. What I do not know is ... what are the early symptoms of neurotoxicity and/or demyelination?... and this is where a neurologist would be able to help you if you are concerned about such side effects. Best regards, Dave (father of (23); PSC 07/03; UC 08/03) > Thanks , I wil take your advise and contact a Neurologist because of the sudden onset. However, I still wonder if it could be a side effect of the Remicade infusions, he has been gettign them for over a year. Quote Link to comment Share on other sites More sharing options...
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