Guest guest Posted January 28, 2009 Report Share Posted January 28, 2009 I have small duct PSC - what it means is that when they do my MRCP and Biopsies that I show that My small ducts are being destroyed but my large ducts or the main Biliary tree has not been attacked to much yet. For me, My last MRCP indicated that I was begining to develop large duct PSC also. Hope this helps Dawn > > How do you know if you have small or large duct PSC? Sounds like it is better to have small duct psc but it also sounds like small duct PSC eventually turns into large duct PSC. Thanks for the good info. > > Lori A. > > " Aggressively Pursuing Solutions To Your Real Estate Needs! " > > First Weber Group > Cell: > 1507 E. Sunset Drive > Waukesha, WI 53189 > LoriUSA@... > www.Lori.FirstWeber.com > > > > > > ________________________________ > From: > To: > Sent: Tuesday, January 27, 2009 10:18:55 PM > Subject: Small-duct PSC > > > Curr Gastroenterol Rep. 2009 Feb;11(1):37- 41. > > Small-duct primary sclerosing cholangitis. > > Björnsson E > > Department of Internal Medicine, Section of Gastroenterology and > Hepatology, Sahlgrenska University Hospital, Med pol II, SE-413 45 > Gothenburg, Sweden. einar.bjornsson@ medic.gu. se. > > Patients with cholestatic liver tests and typical histologic features > of primary sclerosing cholangitis (PSC) but a normal cholangiogram > have been identified as having small-duct PSC. This subgroup of PSC > has been less well characterized than the classic large-duct form. > Some patients characterized as having small-duct PSC develop > cholangiographic features of PSC during follow-up. Three papers > published in 2002 on small-duct PSC patients suggested a better > prognosis in patients with small-duct PSC than in those with large- > duct PSC. However, these studies included a limited number of > patients and had a short follow-up. A combined cohort of these > patients with a prolonged follow-up recently confirmed these previous > observations. However, some patients will suffer from liver-related > mortality or will need to undergo liver transplantation. Recurrence > of small-duct PSC after liver transplantation has been reported. > Cholangiocarcinoma, the most feared complication of PSC, has not been > described in a patient with small-duct PSC without progression first > to large-duct PSC. PMID: 19166657. > > Dave > (father of (23); PSC 07/03; UC 08/03) > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 28, 2009 Report Share Posted January 28, 2009 Interesting article. And it's from Gothenburg, Sweden - where my relatives live. I'm familiar with Sahlgrenska Hospital - I went there when I lived in Sweden (a number of decades ago).Marie To: From: rhodesdavid1@...Date: Wed, 28 Jan 2009 04:18:55 +0000Subject: Small-duct PSC Curr Gastroenterol Rep. 2009 Feb;11(1):37-41. Small-duct primary sclerosing cholangitis. Björnsson E Department of Internal Medicine, Section of Gastroenterology and Hepatology, Sahlgrenska University Hospital, Med pol II, SE-413 45 Gothenburg, Sweden. einar.bjornsson (AT) medic (DOT) gu.se. Patients with cholestatic liver tests and typical histologic features of primary sclerosing cholangitis (PSC) but a normal cholangiogram have been identified as having small-duct PSC. This subgroup of PSC has been less well characterized than the classic large-duct form. Some patients characterized as having small-duct PSC develop cholangiographic features of PSC during follow-up. Three papers published in 2002 on small-duct PSC patients suggested a better prognosis in patients with small-duct PSC than in those with large- duct PSC. However, these studies included a limited number of patients and had a short follow-up. A combined cohort of these patients with a prolonged follow-up recently confirmed these previous observations. However, some patients will suffer from liver-related mortality or will need to undergo liver transplantation. Recurrence of small-duct PSC after liver transplantation has been reported. Cholangiocarcinoma, the most feared complication of PSC, has not been described in a patient with small-duct PSC without progression first to large-duct PSC. PMID: 19166657. Dave (father of (23); PSC 07/03; UC 08/03) Hotmail® goes where you go. On a PC, on the Web, on your phone. See how. Quote Link to comment Share on other sites More sharing options...
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