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I was on Urso for over 17 years – 300

Mg twice a day. The only time I felt fatigued and had an upset stomach,

other than occasionally, was when my Liver numbers were too high. In my

case, it was specifically biliruben that caused the upset stomach. Have

you had labs recently?

Joe

PSC & UC -

1990; Liver Transplant - 2007

From:

[mailto: ] On Behalf Of sikeea_graham

Sent: Tuesday, January 27, 2009

12:41 PM

To:

Subject: I'm on

Urso, but...

I have been on Urso (300 mg 2x a day) for close to 2

years. I hadn't really

noticed many problems, but for the past month, I have been feeling

really fatigued, nauseaus, and feeling like something died in my

stomach. I don't know why, I've even been eating less processed foods.

I guess what I need to know is: has anyone else had problems after

being on Urso for a relatively short period of time? Is it PSC-

related, or not? What can I expect? I feel like I'm back at square one

with docs not really being sure what to do with me. It's even

effecting my job performance, which doesn't help in this recession.

Please help.

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I was on Urso for over 17 years – 300

Mg twice a day. The only time I felt fatigued and had an upset stomach,

other than occasionally, was when my Liver numbers were too high. In my

case, it was specifically biliruben that caused the upset stomach. Have

you had labs recently?

Joe

PSC & UC -

1990; Liver Transplant - 2007

From:

[mailto: ] On Behalf Of sikeea_graham

Sent: Tuesday, January 27, 2009

12:41 PM

To:

Subject: I'm on

Urso, but...

I have been on Urso (300 mg 2x a day) for close to 2

years. I hadn't really

noticed many problems, but for the past month, I have been feeling

really fatigued, nauseaus, and feeling like something died in my

stomach. I don't know why, I've even been eating less processed foods.

I guess what I need to know is: has anyone else had problems after

being on Urso for a relatively short period of time? Is it PSC-

related, or not? What can I expect? I feel like I'm back at square one

with docs not really being sure what to do with me. It's even

effecting my job performance, which doesn't help in this recession.

Please help.

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Share on other sites

I was on Urso for over 17 years – 300

Mg twice a day. The only time I felt fatigued and had an upset stomach,

other than occasionally, was when my Liver numbers were too high. In my

case, it was specifically biliruben that caused the upset stomach. Have

you had labs recently?

Joe

PSC & UC -

1990; Liver Transplant - 2007

From:

[mailto: ] On Behalf Of sikeea_graham

Sent: Tuesday, January 27, 2009

12:41 PM

To:

Subject: I'm on

Urso, but...

I have been on Urso (300 mg 2x a day) for close to 2

years. I hadn't really

noticed many problems, but for the past month, I have been feeling

really fatigued, nauseaus, and feeling like something died in my

stomach. I don't know why, I've even been eating less processed foods.

I guess what I need to know is: has anyone else had problems after

being on Urso for a relatively short period of time? Is it PSC-

related, or not? What can I expect? I feel like I'm back at square one

with docs not really being sure what to do with me. It's even

effecting my job performance, which doesn't help in this recession.

Please help.

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Hi Sikeea,

I’d say that you are having some build-up of liver enzymes and

may be coming down with an infection. Get in to see your doctor and ask for

liver function tests. This is a progressive disease, and after a few years, I’m

not surprised if you are feeling worse.

Nita

for the past month, I have been feeling

really fatigued, nauseaus, and feeling like something died in my

stomach. I don't know why, I've even been eating less processed foods.

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Hi Sikeea,

I’d say that you are having some build-up of liver enzymes and

may be coming down with an infection. Get in to see your doctor and ask for

liver function tests. This is a progressive disease, and after a few years, I’m

not surprised if you are feeling worse.

Nita

for the past month, I have been feeling

really fatigued, nauseaus, and feeling like something died in my

stomach. I don't know why, I've even been eating less processed foods.

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>Thanks, Nita. Wow, I have been bothering my doctors a lot, and even

made an infectious disease specialist referred by my gastro order a

liver panel test with the bloodwork she wanted to do for me. Still

waiting for the results. Also, am taking Nexium because an ENT

thinks I have acid reflux. I wonder if that is a result of the PSC

and Urso, that maybe helping the bile flow better can also make it

accumulate.

>

Hi Sikeea,

>

>

>

> I'd say that you are having some build-up of liver enzymes and may

be coming

> down with an infection. Get in to see your doctor and ask for

liver function

> tests. This is a progressive disease, and after a few years, I'm

not

> surprised if you are feeling worse.

>

>

>

> Nita

>

>

>

> for the past month, I have been feeling

> really fatigued, nauseaus, and feeling like something died in my

> stomach. I don't know why, I've even been eating less processed

foods.

>

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>Thanks, Nita. Wow, I have been bothering my doctors a lot, and even

made an infectious disease specialist referred by my gastro order a

liver panel test with the bloodwork she wanted to do for me. Still

waiting for the results. Also, am taking Nexium because an ENT

thinks I have acid reflux. I wonder if that is a result of the PSC

and Urso, that maybe helping the bile flow better can also make it

accumulate.

>

Hi Sikeea,

>

>

>

> I'd say that you are having some build-up of liver enzymes and may

be coming

> down with an infection. Get in to see your doctor and ask for

liver function

> tests. This is a progressive disease, and after a few years, I'm

not

> surprised if you are feeling worse.

>

>

>

> Nita

>

>

>

> for the past month, I have been feeling

> really fatigued, nauseaus, and feeling like something died in my

> stomach. I don't know why, I've even been eating less processed

foods.

>

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>Yes, I had labs last week and insisted on adding a liver panel to

them. Waiting for the results. I've been passed around from an ENT

who thinks I have a virus and acide reflux, says I should take

Nexium for that, so I have, to my gastro to an infectious disease

specialist. More appointments to come. Weirdly enough, my gastro

thinks it's also a virus, since labs from mid-December didn't show

unusual liver panels. Wonder what he will think of the latest

results. Sounds narcissistic, but I thought that since I was

faithfully taking my Urso and still youngish (not yet 30), that it

would be a while before I had anymore problems. But, I feel that it

is the PSC acting up, because it feels pretty much like before I was

diagnosed, and is inconsistent, unlike a virus.

> I was on Urso for over 17 years - 300 Mg twice a day. The only

time I felt

> fatigued and had an upset stomach, other than occasionally, was

when my

> Liver numbers were too high. In my case, it was specifically

biliruben that

> caused the upset stomach. Have you had labs recently?

>

>

>

> Joe

>

> PSC & UC - 1990; Liver Transplant - 2007

>

> _____

>

> From: [mailto:psc-

support ] On

> Behalf Of sikeea_graham

> Sent: Tuesday, January 27, 2009 12:41 PM

> To:

> Subject: I'm on Urso, but...

>

>

>

> I have been on Urso (300 mg 2x a day) for close to 2 years. I

hadn't really

> noticed many problems, but for the past month, I have been feeling

> really fatigued, nauseaus, and feeling like something died in my

> stomach. I don't know why, I've even been eating less processed

foods.

> I guess what I need to know is: has anyone else had problems after

> being on Urso for a relatively short period of time? Is it PSC-

> related, or not? What can I expect? I feel like I'm back at square

one

> with docs not really being sure what to do with me. It's even

> effecting my job performance, which doesn't help in this

recession.

> Please help.

>

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Share on other sites

>Yes, I had labs last week and insisted on adding a liver panel to

them. Waiting for the results. I've been passed around from an ENT

who thinks I have a virus and acide reflux, says I should take

Nexium for that, so I have, to my gastro to an infectious disease

specialist. More appointments to come. Weirdly enough, my gastro

thinks it's also a virus, since labs from mid-December didn't show

unusual liver panels. Wonder what he will think of the latest

results. Sounds narcissistic, but I thought that since I was

faithfully taking my Urso and still youngish (not yet 30), that it

would be a while before I had anymore problems. But, I feel that it

is the PSC acting up, because it feels pretty much like before I was

diagnosed, and is inconsistent, unlike a virus.

> I was on Urso for over 17 years - 300 Mg twice a day. The only

time I felt

> fatigued and had an upset stomach, other than occasionally, was

when my

> Liver numbers were too high. In my case, it was specifically

biliruben that

> caused the upset stomach. Have you had labs recently?

>

>

>

> Joe

>

> PSC & UC - 1990; Liver Transplant - 2007

>

> _____

>

> From: [mailto:psc-

support ] On

> Behalf Of sikeea_graham

> Sent: Tuesday, January 27, 2009 12:41 PM

> To:

> Subject: I'm on Urso, but...

>

>

>

> I have been on Urso (300 mg 2x a day) for close to 2 years. I

hadn't really

> noticed many problems, but for the past month, I have been feeling

> really fatigued, nauseaus, and feeling like something died in my

> stomach. I don't know why, I've even been eating less processed

foods.

> I guess what I need to know is: has anyone else had problems after

> being on Urso for a relatively short period of time? Is it PSC-

> related, or not? What can I expect? I feel like I'm back at square

one

> with docs not really being sure what to do with me. It's even

> effecting my job performance, which doesn't help in this

recession.

> Please help.

>

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Share on other sites

>Yes, I had labs last week and insisted on adding a liver panel to

them. Waiting for the results. I've been passed around from an ENT

who thinks I have a virus and acide reflux, says I should take

Nexium for that, so I have, to my gastro to an infectious disease

specialist. More appointments to come. Weirdly enough, my gastro

thinks it's also a virus, since labs from mid-December didn't show

unusual liver panels. Wonder what he will think of the latest

results. Sounds narcissistic, but I thought that since I was

faithfully taking my Urso and still youngish (not yet 30), that it

would be a while before I had anymore problems. But, I feel that it

is the PSC acting up, because it feels pretty much like before I was

diagnosed, and is inconsistent, unlike a virus.

> I was on Urso for over 17 years - 300 Mg twice a day. The only

time I felt

> fatigued and had an upset stomach, other than occasionally, was

when my

> Liver numbers were too high. In my case, it was specifically

biliruben that

> caused the upset stomach. Have you had labs recently?

>

>

>

> Joe

>

> PSC & UC - 1990; Liver Transplant - 2007

>

> _____

>

> From: [mailto:psc-

support ] On

> Behalf Of sikeea_graham

> Sent: Tuesday, January 27, 2009 12:41 PM

> To:

> Subject: I'm on Urso, but...

>

>

>

> I have been on Urso (300 mg 2x a day) for close to 2 years. I

hadn't really

> noticed many problems, but for the past month, I have been feeling

> really fatigued, nauseaus, and feeling like something died in my

> stomach. I don't know why, I've even been eating less processed

foods.

> I guess what I need to know is: has anyone else had problems after

> being on Urso for a relatively short period of time? Is it PSC-

> related, or not? What can I expect? I feel like I'm back at square

one

> with docs not really being sure what to do with me. It's even

> effecting my job performance, which doesn't help in this

recession.

> Please help.

>

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Do let us know!

From:

[mailto: ] On Behalf

Of sikeea_graham

Sent: Tuesday, January 27, 2009 7:17 PM

To:

Subject: Re: I'm on Urso, but...

>Yes, I had labs last week and insisted on adding a liver panel to

them. Waiting for the results.

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Do let us know!

From:

[mailto: ] On Behalf

Of sikeea_graham

Sent: Tuesday, January 27, 2009 7:17 PM

To:

Subject: Re: I'm on Urso, but...

>Yes, I had labs last week and insisted on adding a liver panel to

them. Waiting for the results.

Link to comment
Share on other sites

Do let us know!

From:

[mailto: ] On Behalf

Of sikeea_graham

Sent: Tuesday, January 27, 2009 7:17 PM

To:

Subject: Re: I'm on Urso, but...

>Yes, I had labs last week and insisted on adding a liver panel to

them. Waiting for the results.

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Share on other sites

Hi! I'm so sorry to hear you're feeling worse. I have a lot of the symptoms

that you're talking about. I'm not sure what form of Urso you're on, but when I

was on Ursodiol, I was continually in pain, vomiting and nauseous. They

switched me to Urso Forte and that definitely made a difference. As to whether

what's happening to you is PSC related or not, I can't give you an answer. You

may want to ask your doctor about the possibility of something else going on if

you're not sure. At the very least, it might give you piece of mind.

Hope you're feeling better soon!

Sandi in VA

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I also had worse symptoms with regular Ursodiol including horrible headaches. I've been on Urso Forte a year now and tolerate it great and at 12mg/kg. It keeps my liver enzymes down ( accept when I have cholangitis from my stent) SandsUC 2002, PSC 11/07Sent: Thursday, January 29, 2009 5:08 PMTo: Subject: Re: I'm on Urso, but...Hi! I'm so sorry to hear you're feeling worse. I have a lot of the symptoms that you're talking about. I'm not sure what form of Urso you're on, but when I was on Ursodiol, I was continually in pain, vomiting and nauseous. They switched me to Urso Forte and that definitely made a difference. As to whether what's happening to you is PSC related or not, I can't give you an answer. You may want to ask your doctor about the possibility of something else going on if you're not sure. At the very least, it might give you piece of mind. Hope you're feeling better soon! Sandi in VA Messages in this topic (8) Reply (via web post) | [The entire original message is not included]

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I also had worse symptoms with regular Ursodiol including horrible headaches. I've been on Urso Forte a year now and tolerate it great and at 12mg/kg. It keeps my liver enzymes down ( accept when I have cholangitis from my stent) SandsUC 2002, PSC 11/07Sent: Thursday, January 29, 2009 5:08 PMTo: Subject: Re: I'm on Urso, but...Hi! I'm so sorry to hear you're feeling worse. I have a lot of the symptoms that you're talking about. I'm not sure what form of Urso you're on, but when I was on Ursodiol, I was continually in pain, vomiting and nauseous. They switched me to Urso Forte and that definitely made a difference. As to whether what's happening to you is PSC related or not, I can't give you an answer. You may want to ask your doctor about the possibility of something else going on if you're not sure. At the very least, it might give you piece of mind. Hope you're feeling better soon! Sandi in VA Messages in this topic (8) Reply (via web post) | [The entire original message is not included]

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I also had worse symptoms with regular Ursodiol including horrible headaches. I've been on Urso Forte a year now and tolerate it great and at 12mg/kg. It keeps my liver enzymes down ( accept when I have cholangitis from my stent) SandsUC 2002, PSC 11/07Sent: Thursday, January 29, 2009 5:08 PMTo: Subject: Re: I'm on Urso, but...Hi! I'm so sorry to hear you're feeling worse. I have a lot of the symptoms that you're talking about. I'm not sure what form of Urso you're on, but when I was on Ursodiol, I was continually in pain, vomiting and nauseous. They switched me to Urso Forte and that definitely made a difference. As to whether what's happening to you is PSC related or not, I can't give you an answer. You may want to ask your doctor about the possibility of something else going on if you're not sure. At the very least, it might give you piece of mind. Hope you're feeling better soon! Sandi in VA Messages in this topic (8) Reply (via web post) | [The entire original message is not included]

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