Dr Lindor - Complications of ERCP in PSC

[Guest guest]

Endoscopic retrograde cholangiopancreatography

(ERCP) is commonly performed in patients with primary sclerosing cholangitis (PSC). The

risk of complications associated with this procedure is not

well established in these patients. The aim of this retrospective study

was to compare the risk of ERCP complications in PSC vs. non-PSC patients.

http://www.ncbi.nlm.nih.gov/pubmed/19259076

Barb in Texas - Together in the Fight - Whatever it

Takes!

Son Ken (34) UC 91 PSC 99, LTX 6/21 &

6/30 2007 @ Baylor/Dallas

[Guest guest]

Thanks Barb for posting this informative abstract. It reassures that PSC

patients do not have any additional risk while undergoing the ERCP. - Umesh

Dr Lindor - Complications of ERCP in PSC

To:

> Endoscopic retrograde cholangiopancreatography (ERCP) is commonly

> performed in patients with primary sclerosing cholangitis (PSC). The

> risk of complications associated with this procedure is not well

> established in these patients. The aim of this retrospective study was

> to compare the risk of ERCP complications in PSC vs. non-PSC patients.

>

> http://www.ncbi.nlm.nih.gov/pubmed/19259076

>

> Barb in Texas - Together in the Fight - Whatever it Takes!

> Son Ken (34) UC 91 PSC 99, LTX 6/21 & 6/30 2007 @ Baylor/Dallas

>

>

[Guest guest]

Barb,

 

11% is more than 8% and " The incidence of cholangitis was higher in the PSC group (4% vs. 0.2%,P<0.0002) (20 times higher) despite routine use of antibiotics before the procedure in PSC patients " and " CONCLUSIONS:Complications requiring hospitalizations occur in over 10% of PSC patients undergoing ERCP. Cholangitis occurs more often in PSC patients "

 

The increased risk of complications may not negate the requirement and/or benifit of a the procedure, but the report finds there are increased risks despite PSC patients being younger on average.

 

Ian

 

 ----Original Message----- On Behalf Of Ian Cribb

Its nice to know upfront there are more complications with PSC patients and procedure usually take longer.

 

Not sure I agree with you Ian, the way I read it there really weren’t more complications. 

 

“The overall rate of complications in patients with PSC when compared to non-PSC patients was not significantly different (18/168 (11%) vs. 76/981 (8%), P=0.2)  11% vs. 8% isn’t that big of a deal, especially considering all the differences that naturally come with PSC patients.   

 

The risks of complications such as Pancreatitis, perforation, and bleeding were not significantly different between the two groups despite their demographic and procedural variations. 

 

The duration of hospitalization due to complications was also not significantly different between the two groups.

 

I’m didn’t read it the same way you did Ian, sure hope I’m right, the way I read it - is far better news for PSCer’s.

 

Barb in Texas

 

-- Ian Cribb  P.Eng. (6...

[Guest guest]

Barb,

 

11% is more than 8% and " The incidence of cholangitis was higher in the PSC group (4% vs. 0.2%,P<0.0002) (20 times higher) despite routine use of antibiotics before the procedure in PSC patients " and " CONCLUSIONS:Complications requiring hospitalizations occur in over 10% of PSC patients undergoing ERCP. Cholangitis occurs more often in PSC patients "

 

The increased risk of complications may not negate the requirement and/or benifit of a the procedure, but the report finds there are increased risks despite PSC patients being younger on average.

 

Ian

 

 ----Original Message----- On Behalf Of Ian Cribb

Its nice to know upfront there are more complications with PSC patients and procedure usually take longer.

 

Not sure I agree with you Ian, the way I read it there really weren’t more complications. 

 

“The overall rate of complications in patients with PSC when compared to non-PSC patients was not significantly different (18/168 (11%) vs. 76/981 (8%), P=0.2)  11% vs. 8% isn’t that big of a deal, especially considering all the differences that naturally come with PSC patients.   

 

The risks of complications such as Pancreatitis, perforation, and bleeding were not significantly different between the two groups despite their demographic and procedural variations. 

 

The duration of hospitalization due to complications was also not significantly different between the two groups.

 

I’m didn’t read it the same way you did Ian, sure hope I’m right, the way I read it - is far better news for PSCer’s.

 

Barb in Texas

 

-- Ian Cribb  P.Eng. (6...

[Guest guest]

Barb,

 

11% is more than 8% and " The incidence of cholangitis was higher in the PSC group (4% vs. 0.2%,P<0.0002) (20 times higher) despite routine use of antibiotics before the procedure in PSC patients " and " CONCLUSIONS:Complications requiring hospitalizations occur in over 10% of PSC patients undergoing ERCP. Cholangitis occurs more often in PSC patients "

 

The increased risk of complications may not negate the requirement and/or benifit of a the procedure, but the report finds there are increased risks despite PSC patients being younger on average.

 

Ian

 

 ----Original Message----- On Behalf Of Ian Cribb

Its nice to know upfront there are more complications with PSC patients and procedure usually take longer.

 

Not sure I agree with you Ian, the way I read it there really weren’t more complications. 

 

“The overall rate of complications in patients with PSC when compared to non-PSC patients was not significantly different (18/168 (11%) vs. 76/981 (8%), P=0.2)  11% vs. 8% isn’t that big of a deal, especially considering all the differences that naturally come with PSC patients.   

 

The risks of complications such as Pancreatitis, perforation, and bleeding were not significantly different between the two groups despite their demographic and procedural variations. 

 

The duration of hospitalization due to complications was also not significantly different between the two groups.

 

I’m didn’t read it the same way you did Ian, sure hope I’m right, the way I read it - is far better news for PSCer’s.

 

Barb in Texas

 

-- Ian Cribb  P.Eng. (6...