question about liver enzymes

[Guest guest]

My son was first diagnosed with PSC and UC a year ago when all his

liver enzymes were very high,and the ERCP confirmed the PSC.

He has spent the year trying to get his colitis under control and after

dropping 50 pounds and not responding to all the typical medications,

his diarrhea and weight loss seem to be starting to respond to humira.

He had a blood test done in Dec. (he had been off all drugs for a month

and hadn't started humira or urso yet) and all the liver enzymes are

normal on that blood test. Is that typical that they would fluctuate

from very high to normal . . . or might his changes to his diet be

actually helping.

Do PSC patients often have liver enzymes return to normal levels?

[Guest guest]

Thanks so much for your replies.

When first trying to figure out what was wrong, he was told after an

endoscopy that he didn't have celiac disease.

They then did the colonoscopy and said he had serious UC as well as

PSC. They have often referred to the possibility of him having auto

immune hepatitis as well as his psc.

After his initial diagnosis of psc they backtracked because his

liver enzymes went to normal when he was given prednisone

intravenously. (the prednisone did nothing to help the diarhhea so

they weaned him off it) . . . However three months later they were

back telling us that he had psc because of what they observed in an

MRI and then an ERCP.

During the ERCP they didn't mention opening any strictures and his

enzymes didn't improve after his ERCP . . . it wasn't until 6 months

later that they were better.

He hasn't taken any antibiotics.

Throughout all this time his ulcerative colitis and diarrhea has

continued to be bad.

The changes that he made to his diet were no raw vegetables or fruit

as well as no sugar, milk, " fast food " and alcohol. I encouraged no

wheat or yeast and more vegetables but that has been tough to

implement.

[Guest guest]

Thanks so much for your replies.

When first trying to figure out what was wrong, he was told after an

endoscopy that he didn't have celiac disease.

They then did the colonoscopy and said he had serious UC as well as

PSC. They have often referred to the possibility of him having auto

immune hepatitis as well as his psc.

After his initial diagnosis of psc they backtracked because his

liver enzymes went to normal when he was given prednisone

intravenously. (the prednisone did nothing to help the diarhhea so

they weaned him off it) . . . However three months later they were

back telling us that he had psc because of what they observed in an

MRI and then an ERCP.

During the ERCP they didn't mention opening any strictures and his

enzymes didn't improve after his ERCP . . . it wasn't until 6 months

later that they were better.

He hasn't taken any antibiotics.

Throughout all this time his ulcerative colitis and diarrhea has

continued to be bad.

The changes that he made to his diet were no raw vegetables or fruit

as well as no sugar, milk, " fast food " and alcohol. I encouraged no

wheat or yeast and more vegetables but that has been tough to

implement.