Re: MMP-3 gene link to PSC and Scoliosis...anybody else have both ?

[Guest guest]

I just read a report from a CT scan I had last year, and it made an

incidental note of " mild rotatory scoliosis " . I also noticed on another

report it said that I had degenerative bone disease, but my doctors

haven't really discussed either of these with me. I'll have to ask them

about it next time I go in especially since I've been having quite a bit

of back pain recently.

As far as I know I didn't have scoliosis, bone disease, or PSC as a kid

though, so this may not be the same thing...

athan

[Guest guest]

Although I am an adult I have been fighting degenerative disc and

joint disease since I was 13 and I have adult onset Scoliosis, not

bad though, just enough of a twist to get the diagnosis, along with

the PSC. Most of my joints are effected by the degeneration but it

is not considered RA and I have consistently tested NEgative for RA.

No one has ever tied the two together for me.

Dawn

>

> Hi,

>

> Wesley has had PSC since he was 1 years old ( very rare ).

Ulcerative

> Colitis at the same time. I read that the MMP-3 gene etc etc etc

> reasearch links this to a susceptibility to PSC.

>

> Now Wesley has Adolescent Scoliosis which can be caused by the

same

> MMP-3 gene problem which causes inflammation in the bones ( just

like

> the liver )and causes degenerative bone disease which in turn

causes

> scoliosis.

>

> I am taking him to s Hopkins ASAP!

>

> Just wondered who else in this group may have both diseases ???

>

> MARNA and WESLEY ( almost 14....13 years of PSC ...third stage or

> worse)

>