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Re: Periportal Adenopathy????

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Thank you very much Dave

>

> Hi Dawn;

>

> periportal means: situated around the portal vein of the liver.

> http://medical-dictionary.thefreedictionary.com/periportal

>

> adenopathy means: swelling or abnormal enlargement of the lymph nodes.

> http://medical-dictionary.thefreedictionary.com/adenopathy

>

> adenopathy is sometimes called lymphadenopathy, which means: any disorder

characterized by a localized or generalized enlargement of the lymph nodes or

lymph vessels.

> http://medical-dictionary.thefreedictionary.com/Lymphadenopathy

>

> From what I understand, this is not unusual in PSC:

> ________________________

>

> Gastrointest. Radiol. 17: 157-160 (1992)

>

> Lymphadenopathy in sclerosing cholangitis: pitfall in the diagnosis of

malignant biliary obstruction.

>

> Outwater E, Kaplan MM, Bankoff MS

>

> Department of Radiology, New England Medical Center, Boston, Massachusetts.

>

> We retrospectively reviewed abdominal computed tomographic (CT) studies from

20 patients with sclerosing cholangitis and found evidence of abdominal

lymphadenopathy in 13 patients. Enlargement occurred primarily in areas draining

the liver, such as the gastrohepatic ligament or celiac axis (N = 8), the porta

hepatis (N = 7), and the pancreaticoduodenal region (N = 2). One patient had

reactive adenopathy and retroperitoneal fibrosis. The presence of benign

reactive lymphadenopathy in at least one intraabdominal location was confirmed

by pathological examination of excised lymph nodes in seven patients. Malignancy

was excluded by surgical exploration or clinical follow-up. We conclude that

enlarged lymph nodes are a common finding by CT in patients with sclerosing

cholangitis. Enlarged reactive lymph nodes in this condition should not be

mistaken for evidence of periportal metastasis or cholangiocarcinoma. PMID:

1312966.

>

> ________________________

>

> Best regards,

>

> Dave

> (father of (23); PSC 07/03; UC 08/03)

>

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