MED,RES: Recent Patents taken on diagnostic aids and treatments for Chronic Fatigue Syndrome

[Guest guest]

Dear Members,

I have been exploring the US Patent database last week and have found some

interesting new patents regarding the treatment and diagnosis of Chronic

Fatigue Syndrome. The patents are sometimes very techincal but contain very

detailed information.

I have selected 3 interesting patents on Rnase-L, the use of cyclobenzaprine

as sleep aid within CFS and the detection of a Human Blood Bacterium in CFS

patients.

Since the links are too long to paste into an email message, I have uploaded

the 3 articles to my website where you will find a link to the Full-Text of

the Patent.

Here are the Abstracts for each patent:

1)United States Patent 6,207,366

Suhadolnik March 27, 2001

Title: Chronic fatigue syndrome diagnosis

Inventors: Suhadolnik; J. (Roslyn, PA)

Assignee: Temple University- Of the Commonwealth System of Higher Education

(Phila., PA)

Abstract

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Chronic fatigue syndrome is diagnosed through quantification of low and high

molecular weight forms of RNase L in cellular extracts of RNase L-containing

cells such as peripheral blood mononuclear cells.

A ratio of low to high molecular weight RNase L of more than 0.15 is

characteristic of chronic fatigue syndrome.

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2) United States Patent 6,395,788

Iglehart, III May 28, 2002

Title: Methods and compositions for treating or preventing sleep

disturbances and associated illnesses using very low doses of

cyclobenzaprine

Inventors: Iglehart, III; Iredell W. (Baltimore, MD)

Assignee: Vela Pharmaceuticals, Inc. (Lawrenceville, NJ)

Abstract

--------

The present invention relates to methods and compositions comprising a very

low dose of cyclobenzaprine or metabolite thereof for preventing and

treating sleep disturbances and illnesses manifested with sleep dysfunction

including fibromyalgia syndrome, chronic fatigue syndrome, sleep disorders,

psychogenic pain disorders or chronic pain syndromes or symptoms thereof.

The present invention further relates to methods and compositions for

treating sleep disturbances, chronic pain or fatigue in humans suffering

from fibromyalgia syndrome, chronic fatigue syndrome, sleep disorders,

psychogenic pain disorders, chronic pain syndromes using a very low dose of

cyclobenzaprine

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3) United States Patent 6,255,467

Lindner , et al. July 3, 2001

Inventors: Lindner; Luther E. (College Station, TX); MacPhee; Kathleen

(Spring, TX)

Assignee: Pathobiotek Diagnostics Inc. (The Woodlands, TX)

Title: Human blood bacterium

Abstract

--------

The present invention reports a newly-identified human blood bacterium

(HBB), provides characterization, culturing and diagnostic methodologies

therefor and methods for the treatment of pathophysiological states caused

by the bacterium.

The bacterium is apparently present in the bloodstream of all humans in very

low numbers, and appears to be directly or indirectly associated with

several diseases such as chronic fatigue syndrome, multiple sclerosis and

other " autoimmune " diseases. Also provided are uses of engineered HBB

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You can read the patents in full at:

http://www.cfsresearch.org/cfs/whatsnew.htm

WebTV users use this link:

http://www.cfsresearch.org/cfs/whatsnewnf.htm

Nico Vanden Eynde