For Tish Re: Daily thyroid rhythm?

[Guest guest]

In a message dated 3/17/2005 6:06:51 PM Eastern Standard Time,

jeneric46324@... writes:

> Actually the time of day when the TSH and T4 and T3 cross their

> highest peaks is about 2 hours after first rising in the morning. In

> essence it is probably best to take ytou biggest dose first thing in

> the morning on rising.

>

hmmm....i take mine about and hr. or so before rising - or else i'm not so

sure i would rise.

cindi

[Guest guest]

In a message dated 3/17/2005 6:06:51 PM Eastern Standard Time,

jeneric46324@... writes:

> Actually the time of day when the TSH and T4 and T3 cross their

> highest peaks is about 2 hours after first rising in the morning. In

> essence it is probably best to take ytou biggest dose first thing in

> the morning on rising.

>

hmmm....i take mine about and hr. or so before rising - or else i'm not so

sure i would rise.

cindi

[Guest guest]

So, from what you say in this, would it make sense to take more

thyroid later in the day, and not take the highest dose in the

morning? If for example my body can convert T4 to T3, and I also

take Cortef in the morning, theoretically my body would be better

able to use the thyroid I have in me. But later in the day when

cortisol production slows, theoretically T4 to T3 conversion might

slow and I might need more thyroid from an outside source, my

Armour, to have the T3 availbable???? And if I had more in me

weighted to the evening, my body might have more energy available

for repair??? Just asking, because I am wondering if I change how I

dose, it will help eliminate the fluctuations I still seem to be

getting.

R.

>

> I'm pretty sure thyroid function has a rythem. But, it is tied in

> with adrenal function and hard to separate out from it completely.

> Thyroid output seems to be higher at night. Studies have found

that

> the pituitary puts out as much as double the TSH at night in

normal

> healthy people. It is thought that the body does repair and

> maintainance at night and so needs more energy. But, body

> temperature at night is lower than the day. When cortisol is

higher,

> conversion of T4 to T3 increases and thyroid use increases.

Cortisol

> is highest one hour after waking and stays fairly high till about

> noon, but body temperature, a measure of thyroid use in cells, is

> highest somewhere between 11:00 and 2:00. So, there seems to be a

> little delay between the daily cortisol high and the high in

thyroid

> function inside cells. Probably thyroid output from the gland is

> highest at night and tapers down a bit toward morning and then is

> fairly stable through the first half of the day. Then, later in

the

> day when it begins to decline into the evening. Thyroid use in

cells

> is probably highest at night and midday coming in second. Body

> temperature, a measure of metabolic rate in cells, is usually

> highest at midday and drops through the rest of the day and early

> part of the night to the lowest at 12:00 to 3:00 in the morning.

> Cortisol is highest one hour after getting up and drops through

the

> day to the lowest point at about 12:00 to 3:00 in the morning.

>

> Tish