Celiac and Addisons Disease

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Diet and 's Disease

A possible link between gluten sensitivity (celiac disease) and 's

disease has been proposed. An article in the Journal of Endocrinological

Investigation described a patient with celiac disease and multiple endocrine

disorders, including autoimmune 's disease and hypothyroidism

(Valentino et al. 1999). Over a 3-month period, on a gluten-free diet, the

patient showed a marked clinical improvement accompanied by a progressive

decrease in the need for thyroid and adrenal replacement therapies. After 6

months, the serum IgA antiendomysium antibody test (used to confirm celiac

disease) became negative. After 12 months, a new jejunal biopsy showed

complete mucosal recovery. (The jejunum is the middle third of the small

intestine.) After 18 months on a gluten-free diet, the antithyroid

antibodies titer decreased significantly, and thyroid substitutive therapy

was discontinued. The authors proposed a link between autoimmune endocrine

disease and celiac disease, noting that celiac disease is one of the causes

for the failure of substitute hormonal therapy in patients with autoimmune

thyroid disease (Valentino et al. 1999).

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Thyroid-Adrenal Connection Information & Resources

http://www.bestweb.net/~om/thyroid