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Hi,

I had a problem logging in awhile back and had to change my post name slightly,

I am " sbestmom " .

I am a long time member and the occasional poster. Any thoughts on the following

would be greatly appreciated. My 23 yr DD has PSC. Her numbers indicated AIH

overlap, but a biopsy was negative. She was prescribed IMURAN for colitis, and

her liver numbers suddenly improved 40%. She is P ANCA positive, We have been

told her disease is spread thru out her liver. Some areas look completely

normal. She is being listed for transplant, as a precautionary, but with this

marked improvement her meld has dropped. Could this possibly be PSC/ Autoimmune

Cholagitis overlap given her P ANCA is positive? She feels good, but her

numbers were horrible until the Imuran. I am happy but a bit puzzled, and want

to make sure she get the correct treatment.

Thank you, Cathy

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