Fw: [Cangen] Type 1 Diabetes Gene and lupus

[Guest guest]

Since I know at least a couple of the folks on this list have diabetes in

addition to lupus, I thought perhaps this post from a genetics list I am on

might be of interest.

Sue M.

> Another gene contributing to type 1 diabetes has been found. It's related

> to autoimmunity, and dominant in expression.

>

> http://www.sciencedaily.com/releases/2004/07/040712083748.htm

>

> " The mutation we have found is going to increase the responsive capacity

> of the immune system to environmental triggers or stimulators; it makes it

> more reactive, " said Dr. Cong-Yi Wang, molecular geneticist and co-senior

> author.

>

> Dr. Wang and his research team found that when that mutation encounters an

> environmental trigger, such as a bacterial or viral infection, it throws

> off the usual well-balanced activity of the immune system, initiating an

> autoimmune response that eventually attacks the patient's own tissue.

>

> They already are exploring the gene's potential role in other autoimmune

> diseases as well such as lupus, thyroid disease, arthritis and multiple

> sclerosis.

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