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NEWSLINE NOTES

Selected people with ASTHMA should be tested for BACTERIAL LUNG INFECTION.

People with asthma may harbor a bacterial lung infection. In one investigation,

researchers studied 55 people with mild-to-moderate asthma. All had similar

lung function; however, the lungs of 31 (56%) of the participants were infected

with mycoplasma or chlamydia

bacteria. During the course of the study, half of all the participants

(selected randomly) were treated for 6 weeks with the antibiotic clarithromycin; half were given a placebo (inactive

substance). Those who had a bacterial infection and received the antibiotic had

significantly improved lung function. Those who did not receive the antibiotic had

no change in their breathing ability. The researchers suggest that because

tests to identify bacterial lung infections are invasive and disruptive, they

should be limited to include only people who have trouble controlling their

asthma with standard medications. And, antibiotics should not be given to

untested asthma patients in the hope of improving lung function, as it would

contribute to the overuse of antibiotics and emergence of drug-resistant

bacteria. (Chest)

Published: Jan/Feb 2004

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