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Targeted Genetics:

A report on October 4, 2002 at the 16th Annual North American

Cystic Fibrosis Conference in New Orleans is indeed an exciting

step in the Cystic Fibrosis Foundation's effort to develop gene

therapies to treat cystic fibrosis (CF) at the most fundamental

genetic level. Encouraging research sponsored by Targeted

Genetics and conducted in the CF Foundation's Therapeutics

Development Network, show that the adeno-associated virus can be

safely administered in repeated doses to improve the lung

function of CF patients. This is the first report of possible

clinical improvements by the use of CF gene therapy.

Recognizing that this study was conducted in a small number of

patients, Targeted Genetics, working with Cystic Fibrosis

Foundation Therapeutics, is planning new studies to validate

these important findings.

This study was made possible by the ongoing commitment of

Targeted Genetics to bringing this technology forward, and by

the willingness of individuals with CF to participate in these

clinical trials.

We hope to have more to report to you in the months ahead. For

more information, read the official news release from Targeted Genetics.

http://www.cff.org/research/cf_research_in_the_news.cfm?ID=318

________________________________________________________________

Inspire Pharmaceuticals

Early Phase II studies of INS37217 demonstrated some promising

trends in improving lung function in CF patients. As a result,

Cystic Fibrosis Foundation Therapeutics (CFFT) -- the nonprofit

drug development affiliate of the Cystic Fibrosis Foundation --

has entered into an important alliance with Inspire

Pharmaceuticals to further study this compound to validate its

effects in treating cystic fibrosis. A clinical trial is being

planned and will be conducted in the CFFT's Therapeutics

Development Network. This significant collaborative arrangement

will provide a platform to develop therapeutics to attack CF at

its most fundamental molecular level.

Read the official news release from Inspire Pharmaceuticals.

http://www.cff.org/research/cf_research_in_the_news.cfm?ID=320

Becki

YOUR FAVORITE LilGooberGirl

YOUNGLUNG EMAIL SUPPORT LIST

www.topica.com/lists/younglung

Pediatric Interstitial Lung Disease Society

http://groups.yahoo.com/group/InterstitialLung_Kids/

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