Guest guest Posted April 13, 2002 Report Share Posted April 13, 2002 Dr. Nase's intent was to use the small proceeds from the sale of his book to allow him to continue his independent research and advocacy on our behalf. This has not been the reality he had hoped so far because of 2 main reasons - his injury and the lower than expected sales of the book. Geoffrey is one of the best friends that this group could ever hope for. If would be a loss for us all if he is not resourced (i.e. income) such that he can continue his work. davidp. -- Pascoe, mailto:dp@..., South Perth, Western Australia On Saturday, 13 April 2002, at 16:15:45 [GMT -0000] you wrote: e> Patty, can you explain how buying his book supports his ongoing e> research? Or are you referring to something else? e> Marjorie e> Marjorie Lazoff, MD Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 13, 2002 Report Share Posted April 13, 2002 Dr. Nase's intent was to use the small proceeds from the sale of his book to allow him to continue his independent research and advocacy on our behalf. This has not been the reality he had hoped so far because of 2 main reasons - his injury and the lower than expected sales of the book. Geoffrey is one of the best friends that this group could ever hope for. If would be a loss for us all if he is not resourced (i.e. income) such that he can continue his work. davidp. -- Pascoe, mailto:dp@..., South Perth, Western Australia On Saturday, 13 April 2002, at 16:15:45 [GMT -0000] you wrote: e> Patty, can you explain how buying his book supports his ongoing e> research? Or are you referring to something else? e> Marjorie e> Marjorie Lazoff, MD Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 13, 2002 Report Share Posted April 13, 2002 > Dr. Nase's intent was to use the small proceeds from the sale of > his book to allow him to continue his independent research and > advocacy on our behalf. Thanks, . I must be missing something. I'm not familiar with scientific research that's funded by the researcher. Unlike independent filmaking or running for a political office -- both cases where maxing out one's credit cards can pay off in the end -- scientific research is funded by outside sources. That's an important check-and-balance, since whoever funds a research project also maintain a close eye on the process and results, to insure accuracy and give the study credibility. If self-funded, a researcher can report any result -- they don't even have to run an experiment, there's no one to verify anything. That's why one of the main critera in judging the quality of research is who funds the research, and those who have no vested interest in the outcome are considered the most credible, like the government or universities or some private foundations. Certainly, the researcher him/herself has the most vested interest in the outcome of the research, even more than a pharmaceutical company, whose funding is usually viewed as most suspect. Or are you referring to some other kind of independent research, not scientific research performed in a lab? And can you tell us more about " the advocacy on our behalf " ? Do you know what he wants to advocate, and what costs are involved? Perhaps there's something others can do? I tried ordering the book a while ago, but the Web site wasn't functioning properly and there was no easy way for me to purchase the book. I was told that a phone line would be available soon. I see how much Dr. Nase is respected in this group, and how anxious people here are to help him, personally and professionally. Marjorie Marjorie Lazoff, MD Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 13, 2002 Report Share Posted April 13, 2002 > Dr. Nase's intent was to use the small proceeds from the sale of > his book to allow him to continue his independent research and > advocacy on our behalf. Thanks, . I must be missing something. I'm not familiar with scientific research that's funded by the researcher. Unlike independent filmaking or running for a political office -- both cases where maxing out one's credit cards can pay off in the end -- scientific research is funded by outside sources. That's an important check-and-balance, since whoever funds a research project also maintain a close eye on the process and results, to insure accuracy and give the study credibility. If self-funded, a researcher can report any result -- they don't even have to run an experiment, there's no one to verify anything. That's why one of the main critera in judging the quality of research is who funds the research, and those who have no vested interest in the outcome are considered the most credible, like the government or universities or some private foundations. Certainly, the researcher him/herself has the most vested interest in the outcome of the research, even more than a pharmaceutical company, whose funding is usually viewed as most suspect. Or are you referring to some other kind of independent research, not scientific research performed in a lab? And can you tell us more about " the advocacy on our behalf " ? Do you know what he wants to advocate, and what costs are involved? Perhaps there's something others can do? I tried ordering the book a while ago, but the Web site wasn't functioning properly and there was no easy way for me to purchase the book. I was told that a phone line would be available soon. I see how much Dr. Nase is respected in this group, and how anxious people here are to help him, personally and professionally. Marjorie Marjorie Lazoff, MD Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 13, 2002 Report Share Posted April 13, 2002 I just wanted to say I agree, Dr. Nase has done a lot for this group and for the disease itself. It is a shame that his book is not doing better...btw, everyone on the group should have it. Its worth far more than the cost. In general though, you have to write a book like this for the passion of it, because it rarely will make you money and I think he probably knew that getting into it. It just downright sucks that Dr. Nase has been hurt, he has done so much for us. Just wanted to throw my two cents in. Pascoe wrote: >Dr. Nase's intent was to use the small proceeds from the sale of his book >to allow him to continue his independent research and advocacy on our >behalf. This has not been the reality he had hoped so far because of 2 >main reasons - his injury and the lower than expected sales of the book. > >Geoffrey is one of the best friends that this group could ever hope for. >If would be a loss for us all if he is not resourced (i.e. income) such >that he can continue his work. > >davidp. >-- > Pascoe, mailto:dp@..., South Perth, Western Australia > >On Saturday, 13 April 2002, at 16:15:45 [GMT -0000] you wrote: > >e> Patty, can you explain how buying his book supports his ongoing >e> research? Or are you referring to something else? > >e> Marjorie > >e> Marjorie Lazoff, MD > > >-- >Please read the list highlights before posting to the whole group (http://rosacea.ii.net/toc.html). Your post will be delayed if you don't give a meaningful subject or trim your reply text. You must change the subject when replying to a digest ! > >See http://www.drnase.com for info on his recently published book. > >To leave the list send an email to rosacea-support-unsubscribe > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 13, 2002 Report Share Posted April 13, 2002 on 4/13/02 4:48 AM, Pascoe at dp@... wrote: > > Dr. Nase's intent was to use the small proceeds from the sale of his book > to allow him to continue his independent research and advocacy on our > behalf. This has not been the reality he had hoped so far because of 2 > main reasons - his injury and the lower than expected sales of the book. > > Geoffrey is one of the best friends that this group could ever hope for. > If would be a loss for us all if he is not resourced (i.e. income) such > that he can continue his work. > > davidp. I'm glad you posted this. I was not on the list when Dr. Nase was actively posting, though I have gone back to the archives of 98/99 and read quite a few of his posts to the group. I am impressed with his obvious and forthcoming generosity and warm-heartedness. What a doll! I was unaware of the details you mention about his book. Hearing what it could mean I am going to order the book for myself. I very much want to support his effort; even for those who have not read his book he has done so much good. Thanks, carrie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 13, 2002 Report Share Posted April 13, 2002 on 4/13/02 4:48 AM, Pascoe at dp@... wrote: > > Dr. Nase's intent was to use the small proceeds from the sale of his book > to allow him to continue his independent research and advocacy on our > behalf. This has not been the reality he had hoped so far because of 2 > main reasons - his injury and the lower than expected sales of the book. > > Geoffrey is one of the best friends that this group could ever hope for. > If would be a loss for us all if he is not resourced (i.e. income) such > that he can continue his work. > > davidp. I'm glad you posted this. I was not on the list when Dr. Nase was actively posting, though I have gone back to the archives of 98/99 and read quite a few of his posts to the group. I am impressed with his obvious and forthcoming generosity and warm-heartedness. What a doll! I was unaware of the details you mention about his book. Hearing what it could mean I am going to order the book for myself. I very much want to support his effort; even for those who have not read his book he has done so much good. Thanks, carrie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 13, 2002 Report Share Posted April 13, 2002 on 4/13/02 4:48 AM, Pascoe at dp@... wrote: > > Dr. Nase's intent was to use the small proceeds from the sale of his book > to allow him to continue his independent research and advocacy on our > behalf. This has not been the reality he had hoped so far because of 2 > main reasons - his injury and the lower than expected sales of the book. > > Geoffrey is one of the best friends that this group could ever hope for. > If would be a loss for us all if he is not resourced (i.e. income) such > that he can continue his work. > > davidp. I'm glad you posted this. I was not on the list when Dr. Nase was actively posting, though I have gone back to the archives of 98/99 and read quite a few of his posts to the group. I am impressed with his obvious and forthcoming generosity and warm-heartedness. What a doll! I was unaware of the details you mention about his book. Hearing what it could mean I am going to order the book for myself. I very much want to support his effort; even for those who have not read his book he has done so much good. Thanks, carrie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 13, 2002 Report Share Posted April 13, 2002 Hm. Now I know why my last two posts never made it to the list...I forgot to set the " To " field to the group...I've been emailing privately! Anyway...How long does it typically take to receive Dr. Nase's book after ordering? I ordered it well over a month ago and have yet to see it. Another rosacea book I ordered at the same time just arrived early last week, so I still have hope. I'll be checking my Visa card statement for billing information, then following up to make sure my order was received, but I wanted to know what your guys' experience has been regarding how long it takes for delivery. Thanks. - Nimeera > > I'm glad you posted this. I was not on the list when Dr. Nase was actively > posting, though I have gone back to the archives of 98/99 and read quite a > few of his posts to the group. I am impressed with his obvious and > forthcoming generosity and warm-heartedness. What a doll! > > I was unaware of the details you mention about his book. Hearing what it > could mean I am going to order the book for myself. I very much want to > support his effort; even for those who have not read his book he has done so > much good. > > Thanks, > > carrie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 13, 2002 Report Share Posted April 13, 2002 Hm. Now I know why my last two posts never made it to the list...I forgot to set the " To " field to the group...I've been emailing privately! Anyway...How long does it typically take to receive Dr. Nase's book after ordering? I ordered it well over a month ago and have yet to see it. Another rosacea book I ordered at the same time just arrived early last week, so I still have hope. I'll be checking my Visa card statement for billing information, then following up to make sure my order was received, but I wanted to know what your guys' experience has been regarding how long it takes for delivery. Thanks. - Nimeera > > I'm glad you posted this. I was not on the list when Dr. Nase was actively > posting, though I have gone back to the archives of 98/99 and read quite a > few of his posts to the group. I am impressed with his obvious and > forthcoming generosity and warm-heartedness. What a doll! > > I was unaware of the details you mention about his book. Hearing what it > could mean I am going to order the book for myself. I very much want to > support his effort; even for those who have not read his book he has done so > much good. > > Thanks, > > carrie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 13, 2002 Report Share Posted April 13, 2002 Hm. Now I know why my last two posts never made it to the list...I forgot to set the " To " field to the group...I've been emailing privately! Anyway...How long does it typically take to receive Dr. Nase's book after ordering? I ordered it well over a month ago and have yet to see it. Another rosacea book I ordered at the same time just arrived early last week, so I still have hope. I'll be checking my Visa card statement for billing information, then following up to make sure my order was received, but I wanted to know what your guys' experience has been regarding how long it takes for delivery. Thanks. - Nimeera > > I'm glad you posted this. I was not on the list when Dr. Nase was actively > posting, though I have gone back to the archives of 98/99 and read quite a > few of his posts to the group. I am impressed with his obvious and > forthcoming generosity and warm-heartedness. What a doll! > > I was unaware of the details you mention about his book. Hearing what it > could mean I am going to order the book for myself. I very much want to > support his effort; even for those who have not read his book he has done so > much good. > > Thanks, > > carrie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 14, 2002 Report Share Posted April 14, 2002 Nimeera, Did you receive an e-mail acknowledgement of your order? If you didn't, your post may not have been received. I received an e-mail acknowledgement of my order the next business day, and another e-mail when the book shipped about a week later. Total time, less than 2 weeks. Dennis Re: Dr. Nase Book on cea Hm. Now I know why my last two posts never made it to the list...I forgot to set the " To " field to the group...I've been emailing privately! Anyway...How long does it typically take to receive Dr. Nase's book after ordering? I ordered it well over a month ago and have yet to see it. Another rosacea book I ordered at the same time just arrived early last week, so I still have hope. I'll be checking my Visa card statement for billing information, then following up to make sure my order was received, but I wanted to know what your guys' experience has been regarding how long it takes for delivery. Thanks. - Nimeera > > I'm glad you posted this. I was not on the list when Dr. Nase was actively > posting, though I have gone back to the archives of 98/99 and read quite a > few of his posts to the group. I am impressed with his obvious and > forthcoming generosity and warm-heartedness. What a doll! > > I was unaware of the details you mention about his book. Hearing what it > could mean I am going to order the book for myself. I very much want to > support his effort; even for those who have not read his book he has done so > much good. > > Thanks, > > carrie -- Please read the list highlights before posting to the whole group (http://rosacea.ii.net/toc.html). Your post will be delayed if you don't give a meaningful subject or trim your reply text. You must change the subject when replying to a digest ! See http://www.drnase.com for info on his recently published book. To leave the list send an email to rosacea-support-unsubscribe Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 14, 2002 Report Share Posted April 14, 2002 Nimeera, Did you receive an e-mail acknowledgement of your order? If you didn't, your post may not have been received. I received an e-mail acknowledgement of my order the next business day, and another e-mail when the book shipped about a week later. Total time, less than 2 weeks. Dennis Re: Dr. Nase Book on cea Hm. Now I know why my last two posts never made it to the list...I forgot to set the " To " field to the group...I've been emailing privately! Anyway...How long does it typically take to receive Dr. Nase's book after ordering? I ordered it well over a month ago and have yet to see it. Another rosacea book I ordered at the same time just arrived early last week, so I still have hope. I'll be checking my Visa card statement for billing information, then following up to make sure my order was received, but I wanted to know what your guys' experience has been regarding how long it takes for delivery. Thanks. - Nimeera > > I'm glad you posted this. I was not on the list when Dr. Nase was actively > posting, though I have gone back to the archives of 98/99 and read quite a > few of his posts to the group. I am impressed with his obvious and > forthcoming generosity and warm-heartedness. What a doll! > > I was unaware of the details you mention about his book. Hearing what it > could mean I am going to order the book for myself. I very much want to > support his effort; even for those who have not read his book he has done so > much good. > > Thanks, > > carrie -- Please read the list highlights before posting to the whole group (http://rosacea.ii.net/toc.html). Your post will be delayed if you don't give a meaningful subject or trim your reply text. You must change the subject when replying to a digest ! See http://www.drnase.com for info on his recently published book. To leave the list send an email to rosacea-support-unsubscribe Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 14, 2002 Report Share Posted April 14, 2002 Nimeera, Did you receive an e-mail acknowledgement of your order? If you didn't, your post may not have been received. I received an e-mail acknowledgement of my order the next business day, and another e-mail when the book shipped about a week later. Total time, less than 2 weeks. Dennis Re: Dr. Nase Book on cea Hm. Now I know why my last two posts never made it to the list...I forgot to set the " To " field to the group...I've been emailing privately! Anyway...How long does it typically take to receive Dr. Nase's book after ordering? I ordered it well over a month ago and have yet to see it. Another rosacea book I ordered at the same time just arrived early last week, so I still have hope. I'll be checking my Visa card statement for billing information, then following up to make sure my order was received, but I wanted to know what your guys' experience has been regarding how long it takes for delivery. Thanks. - Nimeera > > I'm glad you posted this. I was not on the list when Dr. Nase was actively > posting, though I have gone back to the archives of 98/99 and read quite a > few of his posts to the group. I am impressed with his obvious and > forthcoming generosity and warm-heartedness. What a doll! > > I was unaware of the details you mention about his book. Hearing what it > could mean I am going to order the book for myself. I very much want to > support his effort; even for those who have not read his book he has done so > much good. > > Thanks, > > carrie -- Please read the list highlights before posting to the whole group (http://rosacea.ii.net/toc.html). Your post will be delayed if you don't give a meaningful subject or trim your reply text. You must change the subject when replying to a digest ! See http://www.drnase.com for info on his recently published book. To leave the list send an email to rosacea-support-unsubscribe Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 15, 2002 Report Share Posted April 15, 2002 Marjorie, Your comments are completely reasonable and rational when taken in the broad context of funded science in the US. However, my observation is that the funding model for rosacea is quite unlike any field I have ever seen. If you asked me to take a guess at the total annual funding for rosacea research (EXCLUDING funding from drug companies and others selling their wares), I would say it is less than $1M a year. If I were in a particularly bad mood, I might even suggest that true research funding is really limited to the meager sum (order $100K) provided by the National cea Society. The only reason I put the number higher is there may be some private foundations (perhaps funded by the estates of wealthy, deceased rosaceans) that is driving additional funding. Contrary to what has often been suggested here, research funded by NRS is not driven by a mandate from Galderma: Galderma would have little interest in funding Ethan Lerner's work at Harvard on impact of NO inhibitors on rosacea symptoms. To their credit, NRS funded Ethan to do this work - a grand total of around $20K - possibly renewed for another year at similar level. Publications on Noritate (e.g multicenter study by Dahl etal) - all funded by Dermik... (BTW, this was actually a very solid study, double-blind with reasonable quantification of rosacea symptoms like papule/pustule counts and erythema scores) Publications on photoderm (e.g. Angermeier from Brown Univ) - funded by ESC, sole manufacturer of the machine. I could easily be missing something, but I know of no federally funded work (eg NIH, ...) on rosacea. My guess is the FDA has spent more money investigating impact of accutane (I'm not faulting this at all) than the entire annual budget for rosacea research. As Jonathon Wilkin (head of the dermatology section at the FDA) put it, " no one ever died from rosacea ... " . Not exactly a rallying cry for increased funding for rosacea research ... Rick > > > Dr. Nase's intent was to use the small proceeds from the sale of > > his book to allow him to continue his independent research and > > advocacy on our behalf. > > Thanks, . I must be missing something. I'm not familiar with > scientific research that's funded by the researcher. Unlike > independent filmaking or running for a political office -- both cases > where maxing out one's credit cards can pay off in the end -- > scientific research is funded by outside sources. That's an important > check-and-balance, since whoever funds a research project also > maintain a close eye on the process and results, to insure accuracy > and give the study credibility. If self-funded, a researcher can > report any result -- they don't even have to run an experiment, > there's no one to verify anything. > > That's why one of the main critera in judging the quality of research > is who funds the research, and those who have no vested interest in > the outcome are considered the most credible, like the government or > universities or some private foundations. Certainly, the researcher > him/herself has the most vested interest in the outcome of the > research, even more than a pharmaceutical company, whose funding is > usually viewed as most suspect. > > Or are you referring to some other kind of independent research, not > scientific research performed in a lab? And can you tell us more > about " the advocacy on our behalf " ? Do you know what he wants to > advocate, and what costs are involved? Perhaps there's something > others can do? > > I tried ordering the book a while ago, but the Web site wasn't > functioning properly and there was no easy way for me to purchase the > book. I was told that a phone line would be available soon. > > I see how much Dr. Nase is respected in this group, and how anxious > people here are to help him, personally and professionally. > > Marjorie > > Marjorie Lazoff, MD Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 15, 2002 Report Share Posted April 15, 2002 Marjorie, Your comments are completely reasonable and rational when taken in the broad context of funded science in the US. However, my observation is that the funding model for rosacea is quite unlike any field I have ever seen. If you asked me to take a guess at the total annual funding for rosacea research (EXCLUDING funding from drug companies and others selling their wares), I would say it is less than $1M a year. If I were in a particularly bad mood, I might even suggest that true research funding is really limited to the meager sum (order $100K) provided by the National cea Society. The only reason I put the number higher is there may be some private foundations (perhaps funded by the estates of wealthy, deceased rosaceans) that is driving additional funding. Contrary to what has often been suggested here, research funded by NRS is not driven by a mandate from Galderma: Galderma would have little interest in funding Ethan Lerner's work at Harvard on impact of NO inhibitors on rosacea symptoms. To their credit, NRS funded Ethan to do this work - a grand total of around $20K - possibly renewed for another year at similar level. Publications on Noritate (e.g multicenter study by Dahl etal) - all funded by Dermik... (BTW, this was actually a very solid study, double-blind with reasonable quantification of rosacea symptoms like papule/pustule counts and erythema scores) Publications on photoderm (e.g. Angermeier from Brown Univ) - funded by ESC, sole manufacturer of the machine. I could easily be missing something, but I know of no federally funded work (eg NIH, ...) on rosacea. My guess is the FDA has spent more money investigating impact of accutane (I'm not faulting this at all) than the entire annual budget for rosacea research. As Jonathon Wilkin (head of the dermatology section at the FDA) put it, " no one ever died from rosacea ... " . Not exactly a rallying cry for increased funding for rosacea research ... Rick > > > Dr. Nase's intent was to use the small proceeds from the sale of > > his book to allow him to continue his independent research and > > advocacy on our behalf. > > Thanks, . I must be missing something. I'm not familiar with > scientific research that's funded by the researcher. Unlike > independent filmaking or running for a political office -- both cases > where maxing out one's credit cards can pay off in the end -- > scientific research is funded by outside sources. That's an important > check-and-balance, since whoever funds a research project also > maintain a close eye on the process and results, to insure accuracy > and give the study credibility. If self-funded, a researcher can > report any result -- they don't even have to run an experiment, > there's no one to verify anything. > > That's why one of the main critera in judging the quality of research > is who funds the research, and those who have no vested interest in > the outcome are considered the most credible, like the government or > universities or some private foundations. Certainly, the researcher > him/herself has the most vested interest in the outcome of the > research, even more than a pharmaceutical company, whose funding is > usually viewed as most suspect. > > Or are you referring to some other kind of independent research, not > scientific research performed in a lab? And can you tell us more > about " the advocacy on our behalf " ? Do you know what he wants to > advocate, and what costs are involved? Perhaps there's something > others can do? > > I tried ordering the book a while ago, but the Web site wasn't > functioning properly and there was no easy way for me to purchase the > book. I was told that a phone line would be available soon. > > I see how much Dr. Nase is respected in this group, and how anxious > people here are to help him, personally and professionally. > > Marjorie > > Marjorie Lazoff, MD Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 15, 2002 Report Share Posted April 15, 2002 Marjorie, Your comments are completely reasonable and rational when taken in the broad context of funded science in the US. However, my observation is that the funding model for rosacea is quite unlike any field I have ever seen. If you asked me to take a guess at the total annual funding for rosacea research (EXCLUDING funding from drug companies and others selling their wares), I would say it is less than $1M a year. If I were in a particularly bad mood, I might even suggest that true research funding is really limited to the meager sum (order $100K) provided by the National cea Society. The only reason I put the number higher is there may be some private foundations (perhaps funded by the estates of wealthy, deceased rosaceans) that is driving additional funding. Contrary to what has often been suggested here, research funded by NRS is not driven by a mandate from Galderma: Galderma would have little interest in funding Ethan Lerner's work at Harvard on impact of NO inhibitors on rosacea symptoms. To their credit, NRS funded Ethan to do this work - a grand total of around $20K - possibly renewed for another year at similar level. Publications on Noritate (e.g multicenter study by Dahl etal) - all funded by Dermik... (BTW, this was actually a very solid study, double-blind with reasonable quantification of rosacea symptoms like papule/pustule counts and erythema scores) Publications on photoderm (e.g. Angermeier from Brown Univ) - funded by ESC, sole manufacturer of the machine. I could easily be missing something, but I know of no federally funded work (eg NIH, ...) on rosacea. My guess is the FDA has spent more money investigating impact of accutane (I'm not faulting this at all) than the entire annual budget for rosacea research. As Jonathon Wilkin (head of the dermatology section at the FDA) put it, " no one ever died from rosacea ... " . Not exactly a rallying cry for increased funding for rosacea research ... Rick > > > Dr. Nase's intent was to use the small proceeds from the sale of > > his book to allow him to continue his independent research and > > advocacy on our behalf. > > Thanks, . I must be missing something. I'm not familiar with > scientific research that's funded by the researcher. Unlike > independent filmaking or running for a political office -- both cases > where maxing out one's credit cards can pay off in the end -- > scientific research is funded by outside sources. That's an important > check-and-balance, since whoever funds a research project also > maintain a close eye on the process and results, to insure accuracy > and give the study credibility. If self-funded, a researcher can > report any result -- they don't even have to run an experiment, > there's no one to verify anything. > > That's why one of the main critera in judging the quality of research > is who funds the research, and those who have no vested interest in > the outcome are considered the most credible, like the government or > universities or some private foundations. Certainly, the researcher > him/herself has the most vested interest in the outcome of the > research, even more than a pharmaceutical company, whose funding is > usually viewed as most suspect. > > Or are you referring to some other kind of independent research, not > scientific research performed in a lab? And can you tell us more > about " the advocacy on our behalf " ? Do you know what he wants to > advocate, and what costs are involved? Perhaps there's something > others can do? > > I tried ordering the book a while ago, but the Web site wasn't > functioning properly and there was no easy way for me to purchase the > book. I was told that a phone line would be available soon. > > I see how much Dr. Nase is respected in this group, and how anxious > people here are to help him, personally and professionally. > > Marjorie > > Marjorie Lazoff, MD Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 16, 2002 Report Share Posted April 16, 2002 meant for the group This is a forwarded message To: rosacea-support-owner Cc: Date: Tuesday, April 16, 2002, 11:44:25 AM Subject: Re: Dr. Nase Book on cea ===8<==============Original message text=============== > > > > > Dr. Nase's intent was to use the small proceeds from the sale of > > > his book to allow him to continue his independent research and > > > advocacy on our behalf. > > > > Thanks, . I must be missing something. I'm not familiar with > > scientific research that's funded by the researcher. Unlike > > independent filmaking or running for a political office -- both > cases > > where maxing out one's credit cards can pay off in the end -- > > scientific research is funded by outside sources. That's an > important > > check-and-balance, since whoever funds a research project also > > maintain a close eye on the process and results, to insure accuracy > > and give the study credibility. If self-funded, a researcher can > > report any result -- they don't even have to run an experiment, > > there's no one to verify anything. > > > > That's why one of the main critera in judging the quality of > research > > is who funds the research, and those who have no vested interest in > > the outcome are considered the most credible, like the government > or > > universities or some private foundations. Certainly, the researcher > > him/herself has the most vested interest in the outcome of the > > research, even more than a pharmaceutical company, whose funding is > > usually viewed as most suspect. > > > > Or are you referring to some other kind of independent research, > not > > scientific research performed in a lab? And can you tell us more > > about " the advocacy on our behalf " ? Do you know what he wants to > > advocate, and what costs are involved? Perhaps there's something > > others can do? > > > > I tried ordering the book a while ago, but the Web site wasn't > > functioning properly and there was no easy way for me to purchase > the > > book. I was told that a phone line would be available soon. > > > > I see how much Dr. Nase is respected in this group, and how anxious > > people here are to help him, personally and professionally. > > > > Marjorie > > > > Marjorie Lazoff, MD ===8<===========End of original message text=========== Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 16, 2002 Report Share Posted April 16, 2002 meant for the group This is a forwarded message To: rosacea-support-owner Cc: Date: Tuesday, April 16, 2002, 11:44:25 AM Subject: Re: Dr. Nase Book on cea ===8<==============Original message text=============== > > > > > Dr. Nase's intent was to use the small proceeds from the sale of > > > his book to allow him to continue his independent research and > > > advocacy on our behalf. > > > > Thanks, . I must be missing something. I'm not familiar with > > scientific research that's funded by the researcher. Unlike > > independent filmaking or running for a political office -- both > cases > > where maxing out one's credit cards can pay off in the end -- > > scientific research is funded by outside sources. That's an > important > > check-and-balance, since whoever funds a research project also > > maintain a close eye on the process and results, to insure accuracy > > and give the study credibility. If self-funded, a researcher can > > report any result -- they don't even have to run an experiment, > > there's no one to verify anything. > > > > That's why one of the main critera in judging the quality of > research > > is who funds the research, and those who have no vested interest in > > the outcome are considered the most credible, like the government > or > > universities or some private foundations. Certainly, the researcher > > him/herself has the most vested interest in the outcome of the > > research, even more than a pharmaceutical company, whose funding is > > usually viewed as most suspect. > > > > Or are you referring to some other kind of independent research, > not > > scientific research performed in a lab? And can you tell us more > > about " the advocacy on our behalf " ? Do you know what he wants to > > advocate, and what costs are involved? Perhaps there's something > > others can do? > > > > I tried ordering the book a while ago, but the Web site wasn't > > functioning properly and there was no easy way for me to purchase > the > > book. I was told that a phone line would be available soon. > > > > I see how much Dr. Nase is respected in this group, and how anxious > > people here are to help him, personally and professionally. > > > > Marjorie > > > > Marjorie Lazoff, MD ===8<===========End of original message text=========== Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 16, 2002 Report Share Posted April 16, 2002 I think this message was meant for the group. Matija Date: Tue, 16 Apr 2002 17:53:48 -0000 There IS a lot of indirect research out there that can benefit rosacea sufferers. If you read Dr. Nase's book, you will find a well organized procurement of it. Dr nase tracked it all down and organized it in his book to educate and SPUR FURTHER RESEARCH. He also interviewed many, many doctors and summarized what he learned. Incidently, not long after Dr. Nase published, the NRS funded someone to research on Nitric Oxide. Does anyone know if his book brought on the idea? The book is not his main career. He has a full time job as a microvascular physiologist or something like that on top of it. Funding or no funding Dr. Nases book changed my life for the better. Mine was so incredibly painful and debilitating. Now after reading his book and being a member of this group I am so much better. Thank you, thank you, thank you Dr. Nase!! I hope you can keep up your research. Patty > > > > > > > Dr. Nase's intent was to use the small proceeds from the sale > of > > > > his book to allow him to continue his independent research and > > > > advocacy on our behalf. > > > > > > Thanks, . I must be missing something. I'm not familiar with > > > scientific research that's funded by the researcher. Unlike > > > independent filmaking or running for a political office -- both > > cases > > > where maxing out one's credit cards can pay off in the end - - > > > scientific research is funded by outside sources. That's an > > important > > > check-and-balance, since whoever funds a research project also > > > maintain a close eye on the process and results, to insure > accuracy > > > and give the study credibility. If self-funded, a researcher can > > > report any result -- they don't even have to run an experiment, > > > there's no one to verify anything. > > > > > > That's why one of the main critera in judging the quality of > > research > > > is who funds the research, and those who have no vested interest > in > > > the outcome are considered the most credible, like the government > > or > > > universities or some private foundations. Certainly, the > researcher > > > him/herself has the most vested interest in the outcome of the > > > research, even more than a pharmaceutical company, whose funding > is > > > usually viewed as most suspect. > > > > > > Or are you referring to some other kind of independent research, > > not > > > scientific research performed in a lab? And can you tell us more > > > about " the advocacy on our behalf " ? Do you know what he wants to > > > advocate, and what costs are involved? Perhaps there's something > > > others can do? > > > > > > I tried ordering the book a while ago, but the Web site wasn't > > > functioning properly and there was no easy way for me to purchase > > the > > > book. I was told that a phone line would be available soon. > > > > > > I see how much Dr. Nase is respected in this group, and how > anxious > > > people here are to help him, personally and professionally. > > > > > > Marjorie > > > > > > Marjorie Lazoff, MD > > > > ===8<===========End of original message text=========== Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 16, 2002 Report Share Posted April 16, 2002 I think this message was meant for the group. Matija Date: Tue, 16 Apr 2002 17:53:48 -0000 There IS a lot of indirect research out there that can benefit rosacea sufferers. If you read Dr. Nase's book, you will find a well organized procurement of it. Dr nase tracked it all down and organized it in his book to educate and SPUR FURTHER RESEARCH. He also interviewed many, many doctors and summarized what he learned. Incidently, not long after Dr. Nase published, the NRS funded someone to research on Nitric Oxide. Does anyone know if his book brought on the idea? The book is not his main career. He has a full time job as a microvascular physiologist or something like that on top of it. Funding or no funding Dr. Nases book changed my life for the better. Mine was so incredibly painful and debilitating. Now after reading his book and being a member of this group I am so much better. Thank you, thank you, thank you Dr. Nase!! I hope you can keep up your research. Patty > > > > > > > Dr. Nase's intent was to use the small proceeds from the sale > of > > > > his book to allow him to continue his independent research and > > > > advocacy on our behalf. > > > > > > Thanks, . I must be missing something. I'm not familiar with > > > scientific research that's funded by the researcher. Unlike > > > independent filmaking or running for a political office -- both > > cases > > > where maxing out one's credit cards can pay off in the end - - > > > scientific research is funded by outside sources. That's an > > important > > > check-and-balance, since whoever funds a research project also > > > maintain a close eye on the process and results, to insure > accuracy > > > and give the study credibility. If self-funded, a researcher can > > > report any result -- they don't even have to run an experiment, > > > there's no one to verify anything. > > > > > > That's why one of the main critera in judging the quality of > > research > > > is who funds the research, and those who have no vested interest > in > > > the outcome are considered the most credible, like the government > > or > > > universities or some private foundations. Certainly, the > researcher > > > him/herself has the most vested interest in the outcome of the > > > research, even more than a pharmaceutical company, whose funding > is > > > usually viewed as most suspect. > > > > > > Or are you referring to some other kind of independent research, > > not > > > scientific research performed in a lab? And can you tell us more > > > about " the advocacy on our behalf " ? Do you know what he wants to > > > advocate, and what costs are involved? Perhaps there's something > > > others can do? > > > > > > I tried ordering the book a while ago, but the Web site wasn't > > > functioning properly and there was no easy way for me to purchase > > the > > > book. I was told that a phone line would be available soon. > > > > > > I see how much Dr. Nase is respected in this group, and how > anxious > > > people here are to help him, personally and professionally. > > > > > > Marjorie > > > > > > Marjorie Lazoff, MD > > > > ===8<===========End of original message text=========== Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 17, 2002 Report Share Posted April 17, 2002 > Incidently, not long after Dr. Nase published, the NRS funded > someone to research on Nitric Oxide. Does anyone know if his book > brought on the idea? I can't know Dr. Nase's contribution, which may have been everything, but I would suspect that the researchers (responsible for discovering the identity of the long sought 'endothelial relaxing factor' as nitric oxide in the early 1980s) having just won the 1998 Nobel Prize, had more to do with it. And I'm sure that the research would be conducted at Harvard didn't hurt, either. Research into nitric oxide's role in vasodilation has been hot for many years now, in many areas of medicine. For example, I believe it's how Viagra works. Anyone know the prevailing theory, and evidence, regarding nitric oxide and vascular components of rosacea? (I assume the theory is that easy flushing is related to increased production/decreased destruction/increased sensitivity to nitric oxide to the central face's vasculature, selectively?) Marjorie Marjorie Lazoff, MD Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 18, 2002 Report Share Posted April 18, 2002 Yes, Dr. Nase points this out the fact that NO has been a topic of intense study since it's discovery in his book. I find it really very interesting. He then applies the related research findings to rosacea. His theory is outlined as well. I believe the theory is that we simply have too much Nitric Oxide, but I would have to go back and read it again. He cites supporting medical liturature as well. I assume he is the first to publish about Nitric Oxide as a possible direct cause for rosacea. I was wondering if perhaps the researcher from the NRS got the idea from Dr. Nase. This would be a good thing as a main purpose of the book is to encourage further research. Patty > > Incidently, not long after Dr. Nase published, the NRS funded > > someone to research on Nitric Oxide. Does anyone know if his book > > brought on the idea? > > Patty, vascular research on nitric oxide is a hot topic, ever since > it was identified as the endothelial relaxing factor in the early > 1980s. In fact, the 1998 Nobel Prize went to the original researchers > for their discovery of nitric oxide. I don't know much about it, but > I understand it is of interest to many disorders; for example, I > believe the pharmacology of Viagra involves nitric oxide, and it has > also been postulated in the mechanism of essential hypertension. > > I gather the theory regarding nitric oxide and rosacea involves an > overproduction of NO/increased number or activity of NO > receptors/decreased breakdown of NO/oversensitivity of vascular > smooth muscles, etc. involving the vessels of the central face. Can > someone enlighten me as to the precise theory, and where I might > locate support for the theory in the medical literature? > > Thanks, > > Marjorie > > Marjorie Lazoff, MD Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 18, 2002 Report Share Posted April 18, 2002 Yes, Dr. Nase points this out the fact that NO has been a topic of intense study since it's discovery in his book. I find it really very interesting. He then applies the related research findings to rosacea. His theory is outlined as well. I believe the theory is that we simply have too much Nitric Oxide, but I would have to go back and read it again. He cites supporting medical liturature as well. I assume he is the first to publish about Nitric Oxide as a possible direct cause for rosacea. I was wondering if perhaps the researcher from the NRS got the idea from Dr. Nase. This would be a good thing as a main purpose of the book is to encourage further research. Patty > > Incidently, not long after Dr. Nase published, the NRS funded > > someone to research on Nitric Oxide. Does anyone know if his book > > brought on the idea? > > Patty, vascular research on nitric oxide is a hot topic, ever since > it was identified as the endothelial relaxing factor in the early > 1980s. In fact, the 1998 Nobel Prize went to the original researchers > for their discovery of nitric oxide. I don't know much about it, but > I understand it is of interest to many disorders; for example, I > believe the pharmacology of Viagra involves nitric oxide, and it has > also been postulated in the mechanism of essential hypertension. > > I gather the theory regarding nitric oxide and rosacea involves an > overproduction of NO/increased number or activity of NO > receptors/decreased breakdown of NO/oversensitivity of vascular > smooth muscles, etc. involving the vessels of the central face. Can > someone enlighten me as to the precise theory, and where I might > locate support for the theory in the medical literature? > > Thanks, > > Marjorie > > Marjorie Lazoff, MD Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 18, 2002 Report Share Posted April 18, 2002 Marjorie, If you search in the archives for this group using a Lerner & Harvard search string, you'll find a copy of an abstract that Ethan Lerner, MD, from Harvard Med School wrote about his hypothesis regarding NO and rosacea. It's a very helpful document that I posted during 1/2001 (sorry if I have the month/year wrong). Take care, Matija > > Incidently, not long after Dr. Nase published, the NRS funded > > someone to research on Nitric Oxide. Does anyone know if his book > > brought on the idea? > > Patty, vascular research on nitric oxide is a hot topic, ever since > it was identified as the endothelial relaxing factor in the early > 1980s. In fact, the 1998 Nobel Prize went to the original researchers > for their discovery of nitric oxide. I don't know much about it, but > I understand it is of interest to many disorders; for example, I > believe the pharmacology of Viagra involves nitric oxide, and it has > also been postulated in the mechanism of essential hypertension. > > I gather the theory regarding nitric oxide and rosacea involves an > overproduction of NO/increased number or activity of NO > receptors/decreased breakdown of NO/oversensitivity of vascular > smooth muscles, etc. involving the vessels of the central face. Can > someone enlighten me as to the precise theory, and where I might > locate support for the theory in the medical literature? > > Thanks, > > Marjorie > > Marjorie Lazoff, MD Quote Link to comment Share on other sites More sharing options...
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