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Re: Reply from Dr. Lerner

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Marjorie: It's great to know he is still working on it. I hope he

uncovers some info that will help us.

I wonder why he cannot focus more on rosacea considering the fact

that the NRS gave him the grant money to do it. I feel a little

cheated considering the fact that much of the money is probably

donations from rosacea sufferers. Maybe just a small portion was

given by the NRS.

Patty

>

> I just received a reply from Dr. Ethan Lerner. (He's the physician

> researcher who was given an NRS grant 1-2 years ago for studying

the

> direct effects of nitric oxide (NO) in the skin. You may recall

that

> his mice research found those with high NO skin levels had

> inflammation around their hair shafts. The results of his more

recent

> work measuring NO levels in human skin samples was too early to

> report.)

>

> In his reply, he described his work regarding NO and rosacea as

still

> in the hypothesis stage, meaning he has no direct evidence proving

a

> link between NO (or other peptide vasodilators) and rosacea. It

> sounds like rosacea is not the major thrust of his work, but that's

> not to say that rosacea won't eventually benefit from his work.

He's

> presently performing preliminary (pre-clinical) work on topically

> applied NO inhibitors. I wouldn't expect him to share with me how

> that's going.

>

> I wrote back thanking him for his work on behalf of those with

> rosacea who are anxious for more treatment options, and I requested

> that he keep me posted on his progress.

>

> Marjorie

>

> Marjorie Lazoff, MD

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Why cheated, Patty? Good scientists understand ahead of time all the

potential implications of their work, and use that knowledge to

extend the value of their research and to attract grants. Academic

researchers follow their own interests, as it should be -- they work

on behalf of all society, not just the people who fund them at the

moment. And those who fund academic research understand the work is

being conducted within that context.

Corporate scientists are the ones who work on behalf of whoever pays

them, within pharmaceutical and medical device companies.

I've come to appreciate that realistic hope is what it's all about

with chronic diseases. Anything else is just cruel, and leads to

feelings of being cheated and worse. It's important not to be seduced

by unrealistic expectations (but also not to let maintenance care

become hopeless because that isn't realistic either).

Marjorie

Marjorie Lazoff, MD

> >

> > I just received a reply from Dr. Ethan Lerner. (He's the

physician

> > researcher who was given an NRS grant 1-2 years ago for studying

> the

> > direct effects of nitric oxide (NO) in the skin. You may recall

> that

> > his mice research found those with high NO skin levels had

> > inflammation around their hair shafts. The results of his more

> recent

> > work measuring NO levels in human skin samples was too early to

> > report.)

> >

> > In his reply, he described his work regarding NO and rosacea as

> still

> > in the hypothesis stage, meaning he has no direct evidence

proving

> a

> > link between NO (or other peptide vasodilators) and rosacea. It

> > sounds like rosacea is not the major thrust of his work, but

that's

> > not to say that rosacea won't eventually benefit from his work.

> He's

> > presently performing preliminary (pre-clinical) work on topically

> > applied NO inhibitors. I wouldn't expect him to share with me how

> > that's going.

> >

> > I wrote back thanking him for his work on behalf of those with

> > rosacea who are anxious for more treatment options, and I

requested

> > that he keep me posted on his progress.

> >

> > Marjorie

> >

> > Marjorie Lazoff, MD

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Guest guest

Why cheated, Patty? Good scientists understand ahead of time all the

potential implications of their work, and use that knowledge to

extend the value of their research and to attract grants. Academic

researchers follow their own interests, as it should be -- they work

on behalf of all society, not just the people who fund them at the

moment. And those who fund academic research understand the work is

being conducted within that context.

Corporate scientists are the ones who work on behalf of whoever pays

them, within pharmaceutical and medical device companies.

I've come to appreciate that realistic hope is what it's all about

with chronic diseases. Anything else is just cruel, and leads to

feelings of being cheated and worse. It's important not to be seduced

by unrealistic expectations (but also not to let maintenance care

become hopeless because that isn't realistic either).

Marjorie

Marjorie Lazoff, MD

> >

> > I just received a reply from Dr. Ethan Lerner. (He's the

physician

> > researcher who was given an NRS grant 1-2 years ago for studying

> the

> > direct effects of nitric oxide (NO) in the skin. You may recall

> that

> > his mice research found those with high NO skin levels had

> > inflammation around their hair shafts. The results of his more

> recent

> > work measuring NO levels in human skin samples was too early to

> > report.)

> >

> > In his reply, he described his work regarding NO and rosacea as

> still

> > in the hypothesis stage, meaning he has no direct evidence

proving

> a

> > link between NO (or other peptide vasodilators) and rosacea. It

> > sounds like rosacea is not the major thrust of his work, but

that's

> > not to say that rosacea won't eventually benefit from his work.

> He's

> > presently performing preliminary (pre-clinical) work on topically

> > applied NO inhibitors. I wouldn't expect him to share with me how

> > that's going.

> >

> > I wrote back thanking him for his work on behalf of those with

> > rosacea who are anxious for more treatment options, and I

requested

> > that he keep me posted on his progress.

> >

> > Marjorie

> >

> > Marjorie Lazoff, MD

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