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Re: Reply from Dr. Lerner

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Marjorie: It's great to know he is still working on it. I hope he

uncovers some info that will help us.

I wonder why he cannot focus more on rosacea considering the fact

that the NRS gave him the grant money to do it. I feel a little

cheated considering the fact that much of the money is probably

donations from rosacea sufferers. Maybe just a small portion was

given by the NRS.

Patty

>

> I just received a reply from Dr. Ethan Lerner. (He's the physician

> researcher who was given an NRS grant 1-2 years ago for studying

the

> direct effects of nitric oxide (NO) in the skin. You may recall

that

> his mice research found those with high NO skin levels had

> inflammation around their hair shafts. The results of his more

recent

> work measuring NO levels in human skin samples was too early to

> report.)

>

> In his reply, he described his work regarding NO and rosacea as

still

> in the hypothesis stage, meaning he has no direct evidence proving

a

> link between NO (or other peptide vasodilators) and rosacea. It

> sounds like rosacea is not the major thrust of his work, but that's

> not to say that rosacea won't eventually benefit from his work.

He's

> presently performing preliminary (pre-clinical) work on topically

> applied NO inhibitors. I wouldn't expect him to share with me how

> that's going.

>

> I wrote back thanking him for his work on behalf of those with

> rosacea who are anxious for more treatment options, and I requested

> that he keep me posted on his progress.

>

> Marjorie

>

> Marjorie Lazoff, MD

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