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Long term use of accutane.

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Long term use of low dose accutane has potentially

serious side effects and few patients are appropriate

candidates for therapy. The most devastating side effect is

teratogenicity, but other serious side effects include hyperlipidemia,

neutropenia, anemia, and hepatitis. Mucocutaneous adverse

effects include cheilitis, xerosis, conjunctivitis, urethritis, and

hair loss. Long term use has been associated with the development

of diffuse idiopathic skeletal hyperostosis (DISH). This agent

must be used cautiously and only by physicians who are well

versed in all of its adverse effects.

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> Long term use of low dose accutane has potentially

> serious side effects and few patients are appropriate

> candidates for therapy. The most devastating side effect is

> teratogenicity,

It is not teratogenic for males. And this is really not a

devestating effect for females either because all they need to do is

get on birth control, and the right birth control pill will improve

their rosacea, ie. ortho tri cyclin.

but other serious side effects include hyperlipidemia,

> neutropenia, anemia, and hepatitis. Mucocutaneous adverse

> effects include cheilitis, xerosis, conjunctivitis, urethritis, and

> hair loss.

That is mainly on high dose accutane. Look at some pictures of

patients on high dose accutane. Their skin is extremely dry, the

cheilitis is very bad (if they don't apply vaseline), and then

imagine a rosacea patient on high dose accutane. His face would look

much more horrible that the normal acne patient because there would

be an EXTREME flush in the rosacea prone areas of the face. It would

effectively worsen the rosacea. That is why rosacea sufferes who do

low dose accutane must never exceed 10 mg / day and at the first sign

of xerosis must switch to 10 mg qod and also to not take their

accutane with a very large high fat meal.

The hair loss thing is variable. Different amounts for different

people. Be glad you don't have psoriasis because soriatane causes

much more hair loss than accutane. Which brings up another point.

all the aromatic retinoids are just as tetatogenic as accutane and

they have much much longer half lives, why isn't there a smart

program from those? Anyways. those who tend to hair loss on

accutane should be on 10 mg qod and combine it with either minocyline

or zithromax.

Long term use has been associated with the development

> of diffuse idiopathic skeletal hyperostosis (DISH). This agent

> must be used cautiously and only by physicians who are well

> versed in all of its adverse effects.

>

>

this usually occurs after three or more full doses of accutane. long

term 10 mg qod or 10 mg qd would take decades for this to occur.

you'd probably be long gone before this happens.

once again, it is important when one is on accutane to be acutely

aware if you are one who absorbs more than usual at the 10mg/d dose.

if you flush or you notice your skin too dry, it is time to titrate

the dose back. with rosacea and accutane, less is more.

>

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> Long term use of low dose accutane has potentially

> serious side effects and few patients are appropriate

> candidates for therapy. The most devastating side effect is

> teratogenicity,

It is not teratogenic for males. And this is really not a

devestating effect for females either because all they need to do is

get on birth control, and the right birth control pill will improve

their rosacea, ie. ortho tri cyclin.

but other serious side effects include hyperlipidemia,

> neutropenia, anemia, and hepatitis. Mucocutaneous adverse

> effects include cheilitis, xerosis, conjunctivitis, urethritis, and

> hair loss.

That is mainly on high dose accutane. Look at some pictures of

patients on high dose accutane. Their skin is extremely dry, the

cheilitis is very bad (if they don't apply vaseline), and then

imagine a rosacea patient on high dose accutane. His face would look

much more horrible that the normal acne patient because there would

be an EXTREME flush in the rosacea prone areas of the face. It would

effectively worsen the rosacea. That is why rosacea sufferes who do

low dose accutane must never exceed 10 mg / day and at the first sign

of xerosis must switch to 10 mg qod and also to not take their

accutane with a very large high fat meal.

The hair loss thing is variable. Different amounts for different

people. Be glad you don't have psoriasis because soriatane causes

much more hair loss than accutane. Which brings up another point.

all the aromatic retinoids are just as tetatogenic as accutane and

they have much much longer half lives, why isn't there a smart

program from those? Anyways. those who tend to hair loss on

accutane should be on 10 mg qod and combine it with either minocyline

or zithromax.

Long term use has been associated with the development

> of diffuse idiopathic skeletal hyperostosis (DISH). This agent

> must be used cautiously and only by physicians who are well

> versed in all of its adverse effects.

>

>

this usually occurs after three or more full doses of accutane. long

term 10 mg qod or 10 mg qd would take decades for this to occur.

you'd probably be long gone before this happens.

once again, it is important when one is on accutane to be acutely

aware if you are one who absorbs more than usual at the 10mg/d dose.

if you flush or you notice your skin too dry, it is time to titrate

the dose back. with rosacea and accutane, less is more.

>

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> Long term use of low dose accutane has potentially

> serious side effects and few patients are appropriate

> candidates for therapy. The most devastating side effect is

> teratogenicity,

It is not teratogenic for males. And this is really not a

devestating effect for females either because all they need to do is

get on birth control, and the right birth control pill will improve

their rosacea, ie. ortho tri cyclin.

but other serious side effects include hyperlipidemia,

> neutropenia, anemia, and hepatitis. Mucocutaneous adverse

> effects include cheilitis, xerosis, conjunctivitis, urethritis, and

> hair loss.

That is mainly on high dose accutane. Look at some pictures of

patients on high dose accutane. Their skin is extremely dry, the

cheilitis is very bad (if they don't apply vaseline), and then

imagine a rosacea patient on high dose accutane. His face would look

much more horrible that the normal acne patient because there would

be an EXTREME flush in the rosacea prone areas of the face. It would

effectively worsen the rosacea. That is why rosacea sufferes who do

low dose accutane must never exceed 10 mg / day and at the first sign

of xerosis must switch to 10 mg qod and also to not take their

accutane with a very large high fat meal.

The hair loss thing is variable. Different amounts for different

people. Be glad you don't have psoriasis because soriatane causes

much more hair loss than accutane. Which brings up another point.

all the aromatic retinoids are just as tetatogenic as accutane and

they have much much longer half lives, why isn't there a smart

program from those? Anyways. those who tend to hair loss on

accutane should be on 10 mg qod and combine it with either minocyline

or zithromax.

Long term use has been associated with the development

> of diffuse idiopathic skeletal hyperostosis (DISH). This agent

> must be used cautiously and only by physicians who are well

> versed in all of its adverse effects.

>

>

this usually occurs after three or more full doses of accutane. long

term 10 mg qod or 10 mg qd would take decades for this to occur.

you'd probably be long gone before this happens.

once again, it is important when one is on accutane to be acutely

aware if you are one who absorbs more than usual at the 10mg/d dose.

if you flush or you notice your skin too dry, it is time to titrate

the dose back. with rosacea and accutane, less is more.

>

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