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Reply from Dr. Lerner

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I just received a reply from Dr. Ethan Lerner. (He's the physician

researcher who was given an NRS grant 1-2 years ago for studying the

direct effects of nitric oxide (NO) in the skin. You may recall that

his mice research found those with high NO skin levels had

inflammation around their hair shafts. The results of his more recent

work measuring NO levels in human skin samples was too early to

report.)

In his reply, he described his work regarding NO and rosacea as still

in the hypothesis stage, meaning he has no direct evidence proving a

link between NO (or other peptide vasodilators) and rosacea. It

sounds like rosacea is not the major thrust of his work, but that's

not to say that rosacea won't eventually benefit from his work. He's

presently performing preliminary (pre-clinical) work on topically

applied NO inhibitors. I wouldn't expect him to share with me how

that's going.

I wrote back thanking him for his work on behalf of those with

rosacea who are anxious for more treatment options, and I requested

that he keep me posted on his progress.

Marjorie

Marjorie Lazoff, MD

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