Guest guest Posted May 22, 2002 Report Share Posted May 22, 2002 Hey guys, I've been asked to show this to the group. Cutanix is a small biotech-type company that is coming out with a new product for cea. I'm not sure how well this product will work, but it looks kinda promising. With this Email I have attached a three page document talking about a study done with this product on 20 cea sufferers. It only worked for something like 72% of the people, but for those it worked for, it reduced erythema by 67%, whereas the leading prescription drug (Metrogel) decreased cea severity on average between 50-58%. I've been following this company for a few months now. Originally this product was supposed to be used to treat Seborrheic Dermatitis. Although its role in Seb Derm is not mentioned in this study, from what I hear, it does work really good on Seborrheic Dermatitis, perhaps even better than it works on Eczema or cea. Their website is quite pathetic, but I guess they plan on updating it soon before releasing this new product. The product will be coming to market the first or second week in June, so, their website should be updated by then. Because its pretty weak at the moment, I'm not sure, but I believe this excerp is about the product they are releasing: " Cutanix has identified compounds from a new class of small molecules that we believe could be effective in treating one or more inflammatory skin diseases, such as irritant dermatitis, allergic contact dermatitis, seborrheic dermatitis, atopic dermatitis and psoriasis. These compounds have the ability to block at multiple points the inflammatory cascade central to all such diseases. They do this by attenuating one of the two key signal transduction pathways within cells involved in cells' inflammatory response. This pathway contains the p38 MAP kinease and the AP-1 transcription factor. The other key pathway, which contains the NF-kß transcription factor, does not seem to be affected by these compounds. The fact that these compounds affect only a portion of a cell's inflammatory response mechanism may explain why they do not have side effects like corticosteroids and other immunosuppressive drugs. Enough inflammatory genes are dependent on the p38/AP-1 pathway, however, that inflammation in tissue cannot be sustained if these genes are returned to normal levels of expression. The inflammation winds down over several days, much like a slow leak in a tire. " Since the study was conducted by the company selling the product, I wouldn't be surprised if it was partially biased. Unfortunately, even though I believe they were originally going to attempt to seek FDA approval for this item, it has since been classified as a cosmetic, and therefore not under the regulation of the FDA or something like that.. Not entirely sure. Anyway, even with this being said, this product looks to be about as promising as anything out there, so, you may wanna give it a try, especially if you have a combination of cea and Seb Derm. Sorry for makin' this so long! (I never can seem to say what I'm trying to say without blathering on for ten pages) Adam Quote Link to comment Share on other sites More sharing options...
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