Re: Nicotinamide questions

[Guest guest]

Marjorie,

For some unknown reason, it's hard to find information on Nicomide. I

did find a short blurb from drugstore.com, though it's not a study on

it.

http://www.drugstore.com/pharmacy/prices/drugprice.asp?ndc=65880072660

___________________________________________

Information on Nicomide

Learn more about usage, cautions, and possible side effects.

Tablets

Chemical Name: NICOTINAMIDE (NIK-oh-tin-a-mide), ZINC OXIDE (zink OX-

ide), and FOLIC ACID (FOE-lik AS-id)

Common uses

This medicine is a vitamin and mineral combination used to certain

types of acne (e.g., acne vulgaris or acne rosacea) or other

irritated skin conditions. People who have low levels of

nicotinamide, zinc, or folic acid may develop, or be at increased

risk of developing these types of skin conditions.

________________________________________________________________

I use another form of vitamin B3, otc niacinamide, at 250 - 500 mg a

day. I found this to be very helpful in relieving the pinkness and

keeping pustules and papules at bay. I am a little worried about the

side effects of this myself. From my own small research on the web, I

know that the nicotinamide form of B3 is safer to take on a long term

basis. I may go to my derm and get a px for Nicomide. I think it's

the best oral treatment I've tried for my skin.

I haven't heard of a topical Nicomide. I do remember that the Oil of

Olay company makes a lotion called Total Effects which has niacin in

it. A few posters on the list tried it when it first came out, and it

irritated all of them.

Does that pharmaceutical database you referred to in a message a week

or so ago have any info on oral Nicomide or even a topical Nicomide?

It's really bizarre that such a useful medication doesn't have much

information available on it on the web.

I'll keep on the lookout for any information on this med.

Take care,

Matija

> I searched the Web, this group, Medline, and online medical

databases

> looking for information on Nicomide and its active ingredient,

> nicotinamide. Not much out there. Maybe people here can help me?

>

> (1) I know about the nicotinamide/tetracycline study for bullous

> pemphigus, but that has nothing to do with rosacea. Can anyone

direct

> me to clinical studies on the anti-inflammatory effects on skin

from

> oral nicotinamide? Is there a topical preparation that has been

shown

> safe and effective?

>

> (2) Why take Nicomide and not just supplemental nicotinamide if one

> is already happy with the zinc and folate levels in one's

> multivitamin?

>

> (3) Nicotinamide = niacinamide, right? Are there side effects at

> doses below, say, 1 gram daily? [i know they aren't the same side

> effects (good or bad ones) from niacin/nicotinic acid.]

>

> (4) What's the dose equivalent of niacin? My multivitamin has 125

mg

> of niacin as niacinamide/nicotinic acid. Assuming a 50/50 mixture,

> what dose of nicotinamide is that? [barry Hunt peripherally

addressed

> this in an old post, so if he knows anything more I'd appreciate

the

> information.]

>

> I don't know about taking it, I'm just fact-finding at this point.

I

> know enough to know that I can really hurt myself by loading my

cells

> full of megadoses of a vitamin day after day, even if it's water

> soluable and even if there are no known short-term side effects.

The

> body is such a complicated chemical factory, it has mechanisms for

> dealing with too much of a substance that can escape subtle

detection

> until it's too late. But, from the little I've seen, its proposed

> mechanism of action is very interesting.

>

> Thanks.

>

> Marjorie

>

> Marjorie Lazoff, MD

[Guest guest]

Marjorie,

For some unknown reason, it's hard to find information on Nicomide. I

did find a short blurb from drugstore.com, though it's not a study on

it.

http://www.drugstore.com/pharmacy/prices/drugprice.asp?ndc=65880072660

___________________________________________

Information on Nicomide

Learn more about usage, cautions, and possible side effects.

Tablets

Chemical Name: NICOTINAMIDE (NIK-oh-tin-a-mide), ZINC OXIDE (zink OX-

ide), and FOLIC ACID (FOE-lik AS-id)

Common uses

This medicine is a vitamin and mineral combination used to certain

types of acne (e.g., acne vulgaris or acne rosacea) or other

irritated skin conditions. People who have low levels of

nicotinamide, zinc, or folic acid may develop, or be at increased

risk of developing these types of skin conditions.

________________________________________________________________

I use another form of vitamin B3, otc niacinamide, at 250 - 500 mg a

day. I found this to be very helpful in relieving the pinkness and

keeping pustules and papules at bay. I am a little worried about the

side effects of this myself. From my own small research on the web, I

know that the nicotinamide form of B3 is safer to take on a long term

basis. I may go to my derm and get a px for Nicomide. I think it's

the best oral treatment I've tried for my skin.

I haven't heard of a topical Nicomide. I do remember that the Oil of

Olay company makes a lotion called Total Effects which has niacin in

it. A few posters on the list tried it when it first came out, and it

irritated all of them.

Does that pharmaceutical database you referred to in a message a week

or so ago have any info on oral Nicomide or even a topical Nicomide?

It's really bizarre that such a useful medication doesn't have much

information available on it on the web.

I'll keep on the lookout for any information on this med.

Take care,

Matija

> I searched the Web, this group, Medline, and online medical

databases

> looking for information on Nicomide and its active ingredient,

> nicotinamide. Not much out there. Maybe people here can help me?

>

> (1) I know about the nicotinamide/tetracycline study for bullous

> pemphigus, but that has nothing to do with rosacea. Can anyone

direct

> me to clinical studies on the anti-inflammatory effects on skin

from

> oral nicotinamide? Is there a topical preparation that has been

shown

> safe and effective?

>

> (2) Why take Nicomide and not just supplemental nicotinamide if one

> is already happy with the zinc and folate levels in one's

> multivitamin?

>

> (3) Nicotinamide = niacinamide, right? Are there side effects at

> doses below, say, 1 gram daily? [i know they aren't the same side

> effects (good or bad ones) from niacin/nicotinic acid.]

>

> (4) What's the dose equivalent of niacin? My multivitamin has 125

mg

> of niacin as niacinamide/nicotinic acid. Assuming a 50/50 mixture,

> what dose of nicotinamide is that? [barry Hunt peripherally

addressed

> this in an old post, so if he knows anything more I'd appreciate

the

> information.]

>

> I don't know about taking it, I'm just fact-finding at this point.

I

> know enough to know that I can really hurt myself by loading my

cells

> full of megadoses of a vitamin day after day, even if it's water

> soluable and even if there are no known short-term side effects.

The

> body is such a complicated chemical factory, it has mechanisms for

> dealing with too much of a substance that can escape subtle

detection

> until it's too late. But, from the little I've seen, its proposed

> mechanism of action is very interesting.

>

> Thanks.

>

> Marjorie

>

> Marjorie Lazoff, MD

[Guest guest]

Marjorie,

For some unknown reason, it's hard to find information on Nicomide. I

did find a short blurb from drugstore.com, though it's not a study on

it.

http://www.drugstore.com/pharmacy/prices/drugprice.asp?ndc=65880072660

___________________________________________

Information on Nicomide

Learn more about usage, cautions, and possible side effects.

Tablets

Chemical Name: NICOTINAMIDE (NIK-oh-tin-a-mide), ZINC OXIDE (zink OX-

ide), and FOLIC ACID (FOE-lik AS-id)

Common uses

This medicine is a vitamin and mineral combination used to certain

types of acne (e.g., acne vulgaris or acne rosacea) or other

irritated skin conditions. People who have low levels of

nicotinamide, zinc, or folic acid may develop, or be at increased

risk of developing these types of skin conditions.

________________________________________________________________

I use another form of vitamin B3, otc niacinamide, at 250 - 500 mg a

day. I found this to be very helpful in relieving the pinkness and

keeping pustules and papules at bay. I am a little worried about the

side effects of this myself. From my own small research on the web, I

know that the nicotinamide form of B3 is safer to take on a long term

basis. I may go to my derm and get a px for Nicomide. I think it's

the best oral treatment I've tried for my skin.

I haven't heard of a topical Nicomide. I do remember that the Oil of

Olay company makes a lotion called Total Effects which has niacin in

it. A few posters on the list tried it when it first came out, and it

irritated all of them.

Does that pharmaceutical database you referred to in a message a week

or so ago have any info on oral Nicomide or even a topical Nicomide?

It's really bizarre that such a useful medication doesn't have much

information available on it on the web.

I'll keep on the lookout for any information on this med.

Take care,

Matija

> I searched the Web, this group, Medline, and online medical

databases

> looking for information on Nicomide and its active ingredient,

> nicotinamide. Not much out there. Maybe people here can help me?

>

> (1) I know about the nicotinamide/tetracycline study for bullous

> pemphigus, but that has nothing to do with rosacea. Can anyone

direct

> me to clinical studies on the anti-inflammatory effects on skin

from

> oral nicotinamide? Is there a topical preparation that has been

shown

> safe and effective?

>

> (2) Why take Nicomide and not just supplemental nicotinamide if one

> is already happy with the zinc and folate levels in one's

> multivitamin?

>

> (3) Nicotinamide = niacinamide, right? Are there side effects at

> doses below, say, 1 gram daily? [i know they aren't the same side

> effects (good or bad ones) from niacin/nicotinic acid.]

>

> (4) What's the dose equivalent of niacin? My multivitamin has 125

mg

> of niacin as niacinamide/nicotinic acid. Assuming a 50/50 mixture,

> what dose of nicotinamide is that? [barry Hunt peripherally

addressed

> this in an old post, so if he knows anything more I'd appreciate

the

> information.]

>

> I don't know about taking it, I'm just fact-finding at this point.

I

> know enough to know that I can really hurt myself by loading my

cells

> full of megadoses of a vitamin day after day, even if it's water

> soluable and even if there are no known short-term side effects.

The

> body is such a complicated chemical factory, it has mechanisms for

> dealing with too much of a substance that can escape subtle

detection

> until it's too late. But, from the little I've seen, its proposed

> mechanism of action is very interesting.

>

> Thanks.

>

> Marjorie

>

> Marjorie Lazoff, MD

[Guest guest]

> I use another form of vitamin B3, otc niacinamide, at 250 - 500 mg

a

> day. I found this to be very helpful in relieving the pinkness and

> keeping pustules and papules at bay. I am a little worried about

the

> side effects of this myself. From my own small research on the web,

I

> know that the nicotinamide form of B3 is safer to take on a long

term

> basis. I may go to my derm and get a px for Nicomide. I think it's

> the best oral treatment I've tried for my skin.

I just found an Institute of Medicine report from 1998 that gives the

upper limit of safety for niacin at 35mg/day, but that's based on

flushing (which is not associated with nicotinamide/niacinamide

anyway); there was no toxicity noted for any form of niacin below 1.5

grams. IOM is pretty conservative, so I think you're fine.

If anyone is interested, the summary of their recommendations for all

vitamin B and related vitamins is online at:

http://books.nap.edu/books/0309065542/html/123.html#pagetop

> I haven't heard of a topical Nicomide.

There was one reference to it, but it had no trade name so I suspect

it was a formulation that's not available in the US. Anyway, the

study said that topical preparations don't have the anti-inflammatory

effects, but it wasn't the greatest study. I can't find a study that

talks about oral niacinamide/nicotinamide effecting the skin (other

than the pemphigus study which you already quoted).

> I do remember that the Oil of

> Olay company makes a lotion called Total Effects which has niacin

in

> it. A few posters on the list tried it when it first came out, and

it

> irritated all of them.

Right, I forgot about that. It has something in it I react to, I

forgot what. (Gee, what a surprise -- another new product that our

skins can't tolerate! )

> Does that pharmaceutical database you referred to in a message a

week

> or so ago have any info on oral Nicomide or even a topical

Nicomide?

That was the first place I looked. It only has a summary, not a full

monograph. Very unsatisfying.

> It's really bizarre that such a useful medication doesn't have much

> information available on it on the web.

That's exactly my reaction. I'm still looking in some corners of the

Web, but I expected tons about this, considering all the garbage on

the Web about nonsense things. There's not even a lot of talk in this

group about it.

> I'll keep on the lookout for any information on this med.

Great. I know that you have your magic corners.

I'm going to wait until this ridiculous itching I've got quiets down,

then try it -- like you, the supplement alone, not Nicomide. How long

did it take until you noted an effect? Old posts here talk about as

long as 6 weeks.

I read that supplemental zinc and folate (both of which are in

Nicomide) and Vitamin E (400 IU should be fine) are needed. Anything

else?

Marjorie

Marjorie Lazoff, MD

> > I searched the Web, this group, Medline, and online medical

> databases

> > looking for information on Nicomide and its active ingredient,

> > nicotinamide. Not much out there. Maybe people here can help me?

> >

> > (1) I know about the nicotinamide/tetracycline study for bullous

> > pemphigus, but that has nothing to do with rosacea. Can anyone

> direct

> > me to clinical studies on the anti-inflammatory effects on skin

> from

> > oral nicotinamide? Is there a topical preparation that has been

> shown

> > safe and effective?

> >

> > (2) Why take Nicomide and not just supplemental nicotinamide if

one

> > is already happy with the zinc and folate levels in one's

> > multivitamin?

> >

> > (3) Nicotinamide = niacinamide, right? Are there side effects at

> > doses below, say, 1 gram daily? [i know they aren't the same side

> > effects (good or bad ones) from niacin/nicotinic acid.]

> >

> > (4) What's the dose equivalent of niacin? My multivitamin has 125

> mg

> > of niacin as niacinamide/nicotinic acid. Assuming a 50/50

mixture,

> > what dose of nicotinamide is that? [barry Hunt peripherally

> addressed

> > this in an old post, so if he knows anything more I'd appreciate

> the

> > information.]

> >

> > I don't know about taking it, I'm just fact-finding at this

point.

> I

> > know enough to know that I can really hurt myself by loading my

> cells

> > full of megadoses of a vitamin day after day, even if it's water

> > soluable and even if there are no known short-term side effects.

> The

> > body is such a complicated chemical factory, it has mechanisms

for

> > dealing with too much of a substance that can escape subtle

> detection

> > until it's too late. But, from the little I've seen, its proposed

> > mechanism of action is very interesting.

> >

> > Thanks.

> >

> > Marjorie

> >

> > Marjorie Lazoff, MD

[Guest guest]

> I use another form of vitamin B3, otc niacinamide, at 250 - 500 mg

a

> day. I found this to be very helpful in relieving the pinkness and

> keeping pustules and papules at bay. I am a little worried about

the

> side effects of this myself. From my own small research on the web,

I

> know that the nicotinamide form of B3 is safer to take on a long

term

> basis. I may go to my derm and get a px for Nicomide. I think it's

> the best oral treatment I've tried for my skin.

I just found an Institute of Medicine report from 1998 that gives the

upper limit of safety for niacin at 35mg/day, but that's based on

flushing (which is not associated with nicotinamide/niacinamide

anyway); there was no toxicity noted for any form of niacin below 1.5

grams. IOM is pretty conservative, so I think you're fine.

If anyone is interested, the summary of their recommendations for all

vitamin B and related vitamins is online at:

http://books.nap.edu/books/0309065542/html/123.html#pagetop

> I haven't heard of a topical Nicomide.

There was one reference to it, but it had no trade name so I suspect

it was a formulation that's not available in the US. Anyway, the

study said that topical preparations don't have the anti-inflammatory

effects, but it wasn't the greatest study. I can't find a study that

talks about oral niacinamide/nicotinamide effecting the skin (other

than the pemphigus study which you already quoted).

> I do remember that the Oil of

> Olay company makes a lotion called Total Effects which has niacin

in

> it. A few posters on the list tried it when it first came out, and

it

> irritated all of them.

Right, I forgot about that. It has something in it I react to, I

forgot what. (Gee, what a surprise -- another new product that our

skins can't tolerate! )

> Does that pharmaceutical database you referred to in a message a

week

> or so ago have any info on oral Nicomide or even a topical

Nicomide?

That was the first place I looked. It only has a summary, not a full

monograph. Very unsatisfying.

> It's really bizarre that such a useful medication doesn't have much

> information available on it on the web.

That's exactly my reaction. I'm still looking in some corners of the

Web, but I expected tons about this, considering all the garbage on

the Web about nonsense things. There's not even a lot of talk in this

group about it.

> I'll keep on the lookout for any information on this med.

Great. I know that you have your magic corners.

I'm going to wait until this ridiculous itching I've got quiets down,

then try it -- like you, the supplement alone, not Nicomide. How long

did it take until you noted an effect? Old posts here talk about as

long as 6 weeks.

I read that supplemental zinc and folate (both of which are in

Nicomide) and Vitamin E (400 IU should be fine) are needed. Anything

else?

Marjorie

Marjorie Lazoff, MD

> > I searched the Web, this group, Medline, and online medical

> databases

> > looking for information on Nicomide and its active ingredient,

> > nicotinamide. Not much out there. Maybe people here can help me?

> >

> > (1) I know about the nicotinamide/tetracycline study for bullous

> > pemphigus, but that has nothing to do with rosacea. Can anyone

> direct

> > me to clinical studies on the anti-inflammatory effects on skin

> from

> > oral nicotinamide? Is there a topical preparation that has been

> shown

> > safe and effective?

> >

> > (2) Why take Nicomide and not just supplemental nicotinamide if

one

> > is already happy with the zinc and folate levels in one's

> > multivitamin?

> >

> > (3) Nicotinamide = niacinamide, right? Are there side effects at

> > doses below, say, 1 gram daily? [i know they aren't the same side

> > effects (good or bad ones) from niacin/nicotinic acid.]

> >

> > (4) What's the dose equivalent of niacin? My multivitamin has 125

> mg

> > of niacin as niacinamide/nicotinic acid. Assuming a 50/50

mixture,

> > what dose of nicotinamide is that? [barry Hunt peripherally

> addressed

> > this in an old post, so if he knows anything more I'd appreciate

> the

> > information.]

> >

> > I don't know about taking it, I'm just fact-finding at this

point.

> I

> > know enough to know that I can really hurt myself by loading my

> cells

> > full of megadoses of a vitamin day after day, even if it's water

> > soluable and even if there are no known short-term side effects.

> The

> > body is such a complicated chemical factory, it has mechanisms

for

> > dealing with too much of a substance that can escape subtle

> detection

> > until it's too late. But, from the little I've seen, its proposed

> > mechanism of action is very interesting.

> >

> > Thanks.

> >

> > Marjorie

> >

> > Marjorie Lazoff, MD

[Guest guest]

> I use another form of vitamin B3, otc niacinamide, at 250 - 500 mg

a

> day. I found this to be very helpful in relieving the pinkness and

> keeping pustules and papules at bay. I am a little worried about

the

> side effects of this myself. From my own small research on the web,

I

> know that the nicotinamide form of B3 is safer to take on a long

term

> basis. I may go to my derm and get a px for Nicomide. I think it's

> the best oral treatment I've tried for my skin.

I just found an Institute of Medicine report from 1998 that gives the

upper limit of safety for niacin at 35mg/day, but that's based on

flushing (which is not associated with nicotinamide/niacinamide

anyway); there was no toxicity noted for any form of niacin below 1.5

grams. IOM is pretty conservative, so I think you're fine.

If anyone is interested, the summary of their recommendations for all

vitamin B and related vitamins is online at:

http://books.nap.edu/books/0309065542/html/123.html#pagetop

> I haven't heard of a topical Nicomide.

There was one reference to it, but it had no trade name so I suspect

it was a formulation that's not available in the US. Anyway, the

study said that topical preparations don't have the anti-inflammatory

effects, but it wasn't the greatest study. I can't find a study that

talks about oral niacinamide/nicotinamide effecting the skin (other

than the pemphigus study which you already quoted).

> I do remember that the Oil of

> Olay company makes a lotion called Total Effects which has niacin

in

> it. A few posters on the list tried it when it first came out, and

it

> irritated all of them.

Right, I forgot about that. It has something in it I react to, I

forgot what. (Gee, what a surprise -- another new product that our

skins can't tolerate! )

> Does that pharmaceutical database you referred to in a message a

week

> or so ago have any info on oral Nicomide or even a topical

Nicomide?

That was the first place I looked. It only has a summary, not a full

monograph. Very unsatisfying.

> It's really bizarre that such a useful medication doesn't have much

> information available on it on the web.

That's exactly my reaction. I'm still looking in some corners of the

Web, but I expected tons about this, considering all the garbage on

the Web about nonsense things. There's not even a lot of talk in this

group about it.

> I'll keep on the lookout for any information on this med.

Great. I know that you have your magic corners.

I'm going to wait until this ridiculous itching I've got quiets down,

then try it -- like you, the supplement alone, not Nicomide. How long

did it take until you noted an effect? Old posts here talk about as

long as 6 weeks.

I read that supplemental zinc and folate (both of which are in

Nicomide) and Vitamin E (400 IU should be fine) are needed. Anything

else?

Marjorie

Marjorie Lazoff, MD

> > I searched the Web, this group, Medline, and online medical

> databases

> > looking for information on Nicomide and its active ingredient,

> > nicotinamide. Not much out there. Maybe people here can help me?

> >

> > (1) I know about the nicotinamide/tetracycline study for bullous

> > pemphigus, but that has nothing to do with rosacea. Can anyone

> direct

> > me to clinical studies on the anti-inflammatory effects on skin

> from

> > oral nicotinamide? Is there a topical preparation that has been

> shown

> > safe and effective?

> >

> > (2) Why take Nicomide and not just supplemental nicotinamide if

one

> > is already happy with the zinc and folate levels in one's

> > multivitamin?

> >

> > (3) Nicotinamide = niacinamide, right? Are there side effects at

> > doses below, say, 1 gram daily? [i know they aren't the same side

> > effects (good or bad ones) from niacin/nicotinic acid.]

> >

> > (4) What's the dose equivalent of niacin? My multivitamin has 125

> mg

> > of niacin as niacinamide/nicotinic acid. Assuming a 50/50

mixture,

> > what dose of nicotinamide is that? [barry Hunt peripherally

> addressed

> > this in an old post, so if he knows anything more I'd appreciate

> the

> > information.]

> >

> > I don't know about taking it, I'm just fact-finding at this

point.

> I

> > know enough to know that I can really hurt myself by loading my

> cells

> > full of megadoses of a vitamin day after day, even if it's water

> > soluable and even if there are no known short-term side effects.

> The

> > body is such a complicated chemical factory, it has mechanisms

for

> > dealing with too much of a substance that can escape subtle

> detection

> > until it's too late. But, from the little I've seen, its proposed

> > mechanism of action is very interesting.

> >

> > Thanks.

> >

> > Marjorie

> >

> > Marjorie Lazoff, MD

[Guest guest]

Hi All. I've been using Nacinamide 500 mg/day and a B

complex and Ester C. I have not taken zinc or vitamin

E. Is that a bad thing? Help! How much zinc and E

is recommended???

I used to take a multivitamin but haven't found one

without Niacin. Any suggestions? Michele

> > >

> > > (2) Why take Nicomide and not just supplemental

> nicotinamide if

> one

> > > is already happy with the zinc and folate levels

> in one's

> > > multivitamin?

> > >

> > > (3) Nicotinamide = niacinamide, right? Are there

> side effects at

> > > doses below, say, 1 gram daily? [i know they

> aren't the same side

> > > effects (good or bad ones) from niacin/nicotinic

> acid.]

> > >

> > > (4) What's the dose equivalent of niacin? My

> multivitamin has 125

> > mg

> > > of niacin as niacinamide/nicotinic acid.

> Assuming a 50/50

> mixture,

> > > what dose of nicotinamide is that? [barry Hunt

> peripherally

> > addressed

> > > this in an old post, so if he knows anything

> more I'd appreciate

> > the

> > > information.]

> > >

> > > I don't know about taking it, I'm just

> fact-finding at this

> point.

> > I

> > > know enough to know that I can really hurt

> myself by loading my

> > cells

> > > full of megadoses of a vitamin day after day,

> even if it's water

> > > soluable and even if there are no known

> short-term side effects.

> > The

> > > body is such a complicated chemical factory, it

> has mechanisms

> for

> > > dealing with too much of a substance that can

> escape subtle

> > detection

> > > until it's too late. But, from the little I've

> seen, its proposed

> > > mechanism of action is very interesting.

> > >

> > > Thanks.

> > >

> > > Marjorie

> > >

> > > Marjorie Lazoff, MD

>

>

>

> --

> Please read the list highlights before posting to

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> Your post will be delayed if you don't give a

> meaningful subject or trim your reply text. You must

> change the subject when replying to a digest !

>

> See http://www.drnase.com for info on his recently

> published book.

>

=== message truncated ===

__________________________________________________

[Guest guest]

on 5/2/02 3:05 PM, mschmidt at mschmidt40@... wrote:

>

> Hi All. I've been using Nacinamide 500 mg/day and a B

> complex and Ester C. I have not taken zinc or vitamin

> E. Is that a bad thing? Help! How much zinc and E

> is recommended???

>

> I used to take a multivitamin but haven't found one

> without Niacin. Any suggestions? Michele

Michele,

There are multi's out there made without niacin, but rather with

niacinamide. My multi is from Trader Joe's ( a chain of specialty groceries)

in california. I don't know if this helps you... Do you have Costco where

you are? I'm pretty sure I saw a similar multi there as well.

carrie

[Guest guest]

Hi Marjorie,

It's taken me about two weeks to see the results (fewer bumps and a

shorter lifespan for those that do surface; also the bumps are

smaller). I've noticed that I don't have those awful red marks on my

skin from former bumps. I know I get fewer of them, but I think this

vitamin helps to make those disappear faster too. A less blotchy

complexion is also a benefit I've gotten from it.

I'm unusual in that my skin reacts quickly to oral vitamins. If it

does take you six weeks or more to get benefits from it, it's worth

it if you ask me.

Please let the board know how you do with niacinamide. I'm keeping my

fingers crossed that it helps you like it's helped many here.

Take care,

Matija

> > > I searched the Web, this group, Medline, and online medical

> > databases

> > > looking for information on Nicomide and its active ingredient,

> > > nicotinamide. Not much out there. Maybe people here can help me?

> > >

> > > (1) I know about the nicotinamide/tetracycline study for

bullous

> > > pemphigus, but that has nothing to do with rosacea. Can anyone

> > direct

> > > me to clinical studies on the anti-inflammatory effects on skin

> > from

> > > oral nicotinamide? Is there a topical preparation that has been

> > shown

> > > safe and effective?

> > >

> > > (2) Why take Nicomide and not just supplemental nicotinamide if

> one

> > > is already happy with the zinc and folate levels in one's

> > > multivitamin?

> > >

> > > (3) Nicotinamide = niacinamide, right? Are there side effects

at

> > > doses below, say, 1 gram daily? [i know they aren't the same

side

> > > effects (good or bad ones) from niacin/nicotinic acid.]

> > >

> > > (4) What's the dose equivalent of niacin? My multivitamin has

125

> > mg

> > > of niacin as niacinamide/nicotinic acid. Assuming a 50/50

> mixture,

> > > what dose of nicotinamide is that? [barry Hunt peripherally

> > addressed

> > > this in an old post, so if he knows anything more I'd

appreciate

> > the

> > > information.]

> > >

> > > I don't know about taking it, I'm just fact-finding at this

> point.

> > I

> > > know enough to know that I can really hurt myself by loading my

> > cells

> > > full of megadoses of a vitamin day after day, even if it's

water

> > > soluable and even if there are no known short-term side

effects.

> > The

> > > body is such a complicated chemical factory, it has mechanisms

> for

> > > dealing with too much of a substance that can escape subtle

> > detection

> > > until it's too late. But, from the little I've seen, its

proposed

> > > mechanism of action is very interesting.

> > >

> > > Thanks.

> > >

> > > Marjorie

> > >

> > > Marjorie Lazoff, MD