Re: Product Tolerance /Noritate

[Guest guest]

Hi,

I went to the Dermik site to find out about reported reactions to

Noritate. Apparently, about 1% of their testers had occurrences of

itchy skin, acne and increased flushing when they used Noritate. They

said it wasn't the actual medicine itself (Metronidazole) but one or

more of the vehicle base ingredients. They are purified water USP,

stearic acid NF, glyceryl monostearate NF, glycerin USP,

methylparaben NF, trolamine NF and propylparaben NF. I've heard of

stearic acid causing acne to appear in some people. I haven't heard

of adverse reactions to the other ingredients, except for glycerin

which some rosaceans cannot tolerate. I can use glycerin though.

It's still a mystery which ingredient(s) is the culprit and why it's

a delayed reaction.

Here's the url if anyone is interested:

http://www.dermik.com/pi_products/noritate_pi/noritate_pi.html

Take care,

Matija

> > Strange, isn't it! It really makes no sense at all, especially

when

> I

> > consider that it does seem to be somewhat effective when I first

> use

> > it.

> >

> > I don't know if frequent changes in product tolerance is

> > characteristic of rosacea, but I know it's been a constant issue

> for

> > me. From reading your prior posts, I've gathered that you cannot

> > tolerate Zinco. I used to not be able to tolerate it either as

it

> > made me develop itchy red patches. Now it's the first thing I go

> to

> > to calm down my skin when it's irritated.

[Guest guest]

Yes, Marjorie--My skin is happily much healther than it was when I

couldn't tolerate Zinco! This is thanks to photoderm. I used

absolutely nothing on my skin for about 6 months after starting

photoderm, and only resumed use of topicals out of fear my skin would

worsen if I didn't.

Just a side note about Zinco usage. If I apply it directly to my

skin, it will still itch and burn a little. I make a paste out of it

in my palm ( a dab of shea butter and a dab of zinco) and then apply

it to my face).

As far as the noritate tolerance goes, it's happened to me too many

times for it to be anything else. I've been cycling it for about 7

months now. It's much better than the metro products, though. I

couldn't tolerate them at all.

> > Strange, isn't it! It really makes no sense at all, especially

when

> I

> > consider that it does seem to be somewhat effective when I first

> use

> > it.

> >

> > I don't know if frequent changes in product tolerance is

> > characteristic of rosacea, but I know it's been a constant issue

> for

> > me. From reading your prior posts, I've gathered that you cannot

> > tolerate Zinco. I used to not be able to tolerate it either as

it

> > made me develop itchy red patches. Now it's the first thing I go

> to

> > to calm down my skin when it's irritated.

[Guest guest]

Yes, Marjorie--My skin is happily much healther than it was when I

couldn't tolerate Zinco! This is thanks to photoderm. I used

absolutely nothing on my skin for about 6 months after starting

photoderm, and only resumed use of topicals out of fear my skin would

worsen if I didn't.

Just a side note about Zinco usage. If I apply it directly to my

skin, it will still itch and burn a little. I make a paste out of it

in my palm ( a dab of shea butter and a dab of zinco) and then apply

it to my face).

As far as the noritate tolerance goes, it's happened to me too many

times for it to be anything else. I've been cycling it for about 7

months now. It's much better than the metro products, though. I

couldn't tolerate them at all.

> > Strange, isn't it! It really makes no sense at all, especially

when

> I

> > consider that it does seem to be somewhat effective when I first

> use

> > it.

> >

> > I don't know if frequent changes in product tolerance is

> > characteristic of rosacea, but I know it's been a constant issue

> for

> > me. From reading your prior posts, I've gathered that you cannot

> > tolerate Zinco. I used to not be able to tolerate it either as

it

> > made me develop itchy red patches. Now it's the first thing I go

> to

> > to calm down my skin when it's irritated.

[Guest guest]

Have you considered trying the Sulfacet-R product, ummixed, no Na

Sulfacetamide -- leaving a 5% Sulfur lotion. It is very anti-

inflammatory though use caution if you have dry skin.

>

> I'm still hoping against hope that my itching was from something

> other than Noritate. Without some kind of anti-inflammatory agent

> it's just a matter of weeks before my skin acts up again. Last

night

> I stopped everything other than a tolerant cleanser, and for the

> first time in a week the itching stopped. So it's not a new rosacea

> symptom, it was a product reaction.

>

> Thanks.

>

> Marjorie

>

> Marjorie Lazoff, MD

>