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St 's Wort

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In reviewing SSRI and their efficacy in both psychological and anti-

inflammatory conditions, I see mention of the herbal preparation St.

's Wort as possibly of benefit to both mild

depression/anxiety/social phobia and mild inflammatory conditions. I

don't see much discussion about St 's Wort in this group, and

nothing at all within the past year. Why is that?

(of course I'm not advocating St 's Wort or even suggesting it's

safe and effective, I'm just asking)

Marjorie

Marjorie Lazoff, MD

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<>

as with all

otc

non prescription medications

remember they can be

as hard

on your liver as prescription medications

so

it's a good idea to

monitor doses

check with physicians

(especially if you are taking other drugs

concurrently)

i've heard bad stories

about people inducing liver problems

from incautious use of otc

herbal

stuff.

(incl. my brother ...)

i'm under the impression

that

the liver

cleans

stuff out of the body

(the kidneys, too, right?)

so the more stuff you put into your

blood

the more work the liver has to do ...

any one

(doctor marjorie!)

care to

add or subtract from this thought?

stacey

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Thanks to everyone who replied about St. 's wort. It has

documented anti-inflammatory properties, and mixed but probably valid

anti-depressant features, although both sound mild. As others

mentioned, photosensitivity is a theoretical concern, as are drug-

drug interactions. I had not heard about increased blood flow

(vasodilation) as mentioned below, but it sounds reasonable.

I don't know anything much beyond that, but unlike newer US drugs

(like Serzone, for example) it's been in wide use for many years in

Germany, so there aren't likely to be many serious or life-

threatening surprises (although arguable we don't know how it reacts

within American lifestyles).

Again, I'm certainly not making a recommendation, I was just curious

if anyone had any feedback, one way or the other. Thanks again.

Marjorie

Marjorie Lazoff, MD

> My pharmacist recommended I be cautious if taking St 's Wort

because it increases photosensitivity and also he said it tends to

increase blood flow (in reference to me noting it made my complexion

noticeably red) so would not be suited with some

> conditions. I suspect rosacea might just be one of those

conditions he was referring to, although I wasn't diagnosed until

after that time so it wasn't something I asked him.

>

>

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Thanks to everyone who replied about St. 's wort. It has

documented anti-inflammatory properties, and mixed but probably valid

anti-depressant features, although both sound mild. As others

mentioned, photosensitivity is a theoretical concern, as are drug-

drug interactions. I had not heard about increased blood flow

(vasodilation) as mentioned below, but it sounds reasonable.

I don't know anything much beyond that, but unlike newer US drugs

(like Serzone, for example) it's been in wide use for many years in

Germany, so there aren't likely to be many serious or life-

threatening surprises (although arguable we don't know how it reacts

within American lifestyles).

Again, I'm certainly not making a recommendation, I was just curious

if anyone had any feedback, one way or the other. Thanks again.

Marjorie

Marjorie Lazoff, MD

> My pharmacist recommended I be cautious if taking St 's Wort

because it increases photosensitivity and also he said it tends to

increase blood flow (in reference to me noting it made my complexion

noticeably red) so would not be suited with some

> conditions. I suspect rosacea might just be one of those

conditions he was referring to, although I wasn't diagnosed until

after that time so it wasn't something I asked him.

>

>

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Thanks to everyone who replied about St. 's wort. It has

documented anti-inflammatory properties, and mixed but probably valid

anti-depressant features, although both sound mild. As others

mentioned, photosensitivity is a theoretical concern, as are drug-

drug interactions. I had not heard about increased blood flow

(vasodilation) as mentioned below, but it sounds reasonable.

I don't know anything much beyond that, but unlike newer US drugs

(like Serzone, for example) it's been in wide use for many years in

Germany, so there aren't likely to be many serious or life-

threatening surprises (although arguable we don't know how it reacts

within American lifestyles).

Again, I'm certainly not making a recommendation, I was just curious

if anyone had any feedback, one way or the other. Thanks again.

Marjorie

Marjorie Lazoff, MD

> My pharmacist recommended I be cautious if taking St 's Wort

because it increases photosensitivity and also he said it tends to

increase blood flow (in reference to me noting it made my complexion

noticeably red) so would not be suited with some

> conditions. I suspect rosacea might just be one of those

conditions he was referring to, although I wasn't diagnosed until

after that time so it wasn't something I asked him.

>

>

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