Immune-mediated disorder & LGS

[Guest guest]

Hi all and hope I haven't caught you in the middle of a flush!

I have spent the last few hours reading through an enormous amount of very

interesting e-mails from this group - and although I've said it before - I

conclude that I have to say it again -

" I think your ALL splendid "

The amount of effort and time that members put in, is " my hope " for a future

cure. I just wish I had the academic genius to help more.

Anyway, I do have a question - academics, long/short term sufferers, anyone

connected to rosacea, your comments are very valuable to me.

Of interest to me is " leaky gut syndrome " and " immune-mediated disorder " .

Could the source of the immune-mediated disorder come initially from a leaky

gut problem?

I find these two topics VERY interesting in themselves but also in relation

to eachother.

What do you think? or.... am I just suffering with brain fog again!!!

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[Guest guest]

Suzi wrote:

> There is a group member (Mark B.) who advances the

> theory that leaky gut is caused by the overuse of

> NSAIDS (advil, motrin, etc.) He says that the drugs

> cause increased permetability of the gut lining,

> allowing the molecules of partially- or un-digested

> food to be exposed to our blood stream. The result is

> an increase in histamine responses and presumably,

> immune responses

I find this interesting, too. I am definitely guilty of excessive use of

Advil, though I always tried to take it with food. I used to be a frequent

headache sufferer, sometimes the headache would last a couple of days. A lot

my headaches were eye related and after I had an eye surgery in October '99,

their number dropped significantly.

I haven't had a headache since I started my diet, as I mentioned last week.

(the only exception was a mild headache associated with my period and I did

take one Advil for that).

I believe the theories about the food, stress etc. relationship, and this

one about Advil does make sense. However, I wish I could find an answer to

my question why my rosacea flared up about 4 years after the eye surgery

(less headaches -> less Advil) and 2 years after I went through major, and I

mean m.a.j.o.r, stress. Well who knows ... maybe I am just an extremely

resilient specimen

Alena

[Guest guest]

Suzi said in part:

>As you may know, I'm pretty sure my (mis) diagnosis of

rosacea is actually related to some sort of histamine

response to foods, maybe with the inability to digest

gluten. I also think that quite a few people

participating may be experiencing something similar.

Many of us have bumps, flushing, flaky patches,

itching, etc. without the classic permanent pinkness

and fine textured rash.

I'm curious. Does this mean that people with rosacea present only with

a fine textured rash? I have never had a rash of any type and have been

flushing for years. I've always been described as having that Irish

type skin which has a rosy glow, and as time went on I never needed to

tan my face because it already looked red. Nowadays I flush

(particularly when exposed to dairy, but also from red wine & tomatoes)

and I have a fairly constant ruddiness about my face (particularly

cheeks and around the base of my nose) which is becoming increasing

worse as blood vessels break and/or remain dilated. When I

inadvertently eat dairy, my face burns. The dermatologist didn't ask me

any details, but had a look at my skin, removed some obvious damaged

blood vessels and declared it was rosacea.

I know my cousin had a rash which looked a lot like severe acne and was

told she had rosacea. She's never looked ruddy. Her complexion is very

pale except for the rashes she gets on her face. How many ways does

rosacea present itself? Are these a cluster of different disorders

grouped under one heading because of the underlying unknown cause?