Immune-mediated disorder & LGS

[Guest guest]

Hi all and hope I haven't caught you in the middle of a flush!

I have spent the last few hours reading through an enormous amount of very

interesting e-mails from this group - and although I've said it before - I

conclude that I have to say it again -

" I think your ALL splendid "

The amount of effort and time that members put in, is " my hope " for a future

cure. I just wish I had the academic genius to help more.

Anyway, I do have a question - academics, long/short term sufferers, anyone

connected to rosacea, your comments are very valuable to me.

Of interest to me is " leaky gut syndrome " and " immune-mediated disorder " .

Could the source of the immune-mediated disorder come initially from a leaky

gut problem?

I find these two topics VERY interesting in themselves but also in relation

to eachother.

What do you think? or.... am I just suffering with brain fog again!!!

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[Guest guest]

There is a group member (Mark B.) who advances the

theory that leaky gut is caused by the overuse of

NSAIDS (advil, motrin, etc.) He says that the drugs

cause increased permetability of the gut lining,

allowing the molecules of partially- or un-digested

food to be exposed to our blood stream. The result is

an increase in histamine responses and presumably,

immune responses.

It's an interesting theory.

I was a HUGE user of Advil for many years, using to

control arthritis in a couple of my joints, and

migraine headaches, and flushing.

As you may know, I'm pretty sure my (mis) diagnosis of

rosacea is actually related to some sort of histamine

response to foods, maybe with the inability to digest

gluten. I also think that quite a few people

participating may be experiencing something similar.

Many of us have bumps, flushing, flakey patches,

itching, etc. without the classic permanent pinkness

and fine textured rash.

For what it's worth, I don't have any complaints from

my arthritis now, headaches are mild and much more

rare, and I rarely flush (where I do, there is a clear

connection to something I ate).

Maybe Mark B. will weigh in on this.

Suzi

__________________________________________________

[Guest guest]

There is a group member (Mark B.) who advances the

theory that leaky gut is caused by the overuse of

NSAIDS (advil, motrin, etc.) He says that the drugs

cause increased permetability of the gut lining,

allowing the molecules of partially- or un-digested

food to be exposed to our blood stream. The result is

an increase in histamine responses and presumably,

immune responses.

It's an interesting theory.

I was a HUGE user of Advil for many years, using to

control arthritis in a couple of my joints, and

migraine headaches, and flushing.

As you may know, I'm pretty sure my (mis) diagnosis of

rosacea is actually related to some sort of histamine

response to foods, maybe with the inability to digest

gluten. I also think that quite a few people

participating may be experiencing something similar.

Many of us have bumps, flushing, flakey patches,

itching, etc. without the classic permanent pinkness

and fine textured rash.

For what it's worth, I don't have any complaints from

my arthritis now, headaches are mild and much more

rare, and I rarely flush (where I do, there is a clear

connection to something I ate).

Maybe Mark B. will weigh in on this.

Suzi

__________________________________________________

[Guest guest]

There is a group member (Mark B.) who advances the

theory that leaky gut is caused by the overuse of

NSAIDS (advil, motrin, etc.) He says that the drugs

cause increased permetability of the gut lining,

allowing the molecules of partially- or un-digested

food to be exposed to our blood stream. The result is

an increase in histamine responses and presumably,

immune responses.

It's an interesting theory.

I was a HUGE user of Advil for many years, using to

control arthritis in a couple of my joints, and

migraine headaches, and flushing.

As you may know, I'm pretty sure my (mis) diagnosis of

rosacea is actually related to some sort of histamine

response to foods, maybe with the inability to digest

gluten. I also think that quite a few people

participating may be experiencing something similar.

Many of us have bumps, flushing, flakey patches,

itching, etc. without the classic permanent pinkness

and fine textured rash.

For what it's worth, I don't have any complaints from

my arthritis now, headaches are mild and much more

rare, and I rarely flush (where I do, there is a clear

connection to something I ate).

Maybe Mark B. will weigh in on this.

Suzi

__________________________________________________

[Guest guest]

Suzi wrote:

> There is a group member (Mark B.) who advances the

> theory that leaky gut is caused by the overuse of

> NSAIDS (advil, motrin, etc.) He says that the drugs

> cause increased permetability of the gut lining,

> allowing the molecules of partially- or un-digested

> food to be exposed to our blood stream. The result is

> an increase in histamine responses and presumably,

> immune responses

I find this interesting, too. I am definitely guilty of excessive use of

Advil, though I always tried to take it with food. I used to be a frequent

headache sufferer, sometimes the headache would last a couple of days. A lot

my headaches were eye related and after I had an eye surgery in October '99,

their number dropped significantly.

I haven't had a headache since I started my diet, as I mentioned last week.

(the only exception was a mild headache associated with my period and I did

take one Advil for that).

I believe the theories about the food, stress etc. relationship, and this

one about Advil does make sense. However, I wish I could find an answer to

my question why my rosacea flared up about 4 years after the eye surgery

(less headaches -> less Advil) and 2 years after I went through major, and I

mean m.a.j.o.r, stress. Well who knows ... maybe I am just an extremely

resilient specimen

Alena