Nocturnal oximetry in infants with cystic fibrosis

[Guest guest]

Hi,

this should read familar to Jennie Uphoff and some others too.

Peace

Torsten, dad of Fiona 5wcf

e-mail: torstenkrafft@...

Arch Dis Child 2001;84:50-54 ( January )

Nocturnal oximetry in infants with cystic fibrosis

M P Villaa, J Pagania, V Lucidib, S Palamidesa, R Ronchettiaa Clinica

Pediatrica, Università " La Sapienza " , Viale Regina Elena, 324, I-00161

Rome, Italy, b Bambino Gesù Hospital, Rome, Italy

Correspondence to: Prof. Villa mariapia.villa@... Accepted 15

August 2000

AIM To investigate whether children with cystic fibrosis under 3 years of

age have disordered breathing and episodes of oxygen desaturation during

sleep.

METHODS We studied 19 infants (9 boys and 10 girls) with cystic fibrosis,

mean age 13.1 months (range 3-36 months) and 20 age and sex matched healthy

subjects. Patients and controls underwent an overnight

polysomnographic study and respiratory function testing on the following

morning.

RESULTS Seven patients with ongoing respiratory tract inflammation had

disordered breathing and episodes of oxygen desaturation during sleep. Pulse

oximetry showed a significantly lower mean oxygen saturation (SaO2)

and a higher percentage of total sleep time spent with SaO2 less than 93% in

symptomatic children than in controls.

CONCLUSION Results suggest that infants and young children with cystic

fibrosis and mild airways inflammation (rhinitis, cough, red throat) have

episodes of oxygen desaturation during sleep.