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Re: Emarjency, I have a question if you don't mind

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Ricky4bbw, I don't really know, my enthusiasm has waned somewhat

after speaking to the medical representative of the pharmaceutical

company. I asked, and he told that zinc oxide and folic acid were

added because each has also been shown to possess anti-inflammatory

properties. He didn't sound very convinced about this, he was far

more excited about the potentials of niacinamide, but it doesn't

sound like they are needed, at least not from his knowledge base.

Interesting, that the Nicomide is prescription not because of the

niacinamide but only because of the dose of folic acid. I don't know

why folic acid in high doses is restricted, and he couldn't tell me

either.

My knowledge of nutrition is very limited, and I hope those with more

knowledge will " supplement " my words.

From what I understand, zinc can function in the body as an oxidizing

agent (defeating the purpose of anti-oxidants), so like iron and

copper, I would not intuitively recommend supplementing more than the

minimum daily requirements (which for zinc is 15 mg.) Each Nicomide

contains 25 mg, so that would total 50 mg a day. Also, zinc and

copper compete for absorption, so at such doses copper deficiency is

theoretically possible over long term.

Daily requirements for folic acid are 400mg. Each Nicomide contains

500 mg, and is recommended to be taken twice a day.

The company is looking to manufacture 4% niacinamide cream (without

other additives), but he couldn't give me a time frame. It's not

presently available in the US, though he couldn't tell me why.

Obviously the guy wasn't a warehouse of information beyond what he

wanted me to know through promoting his product (which, curiously,

wasn't more than I had already picked up about niacinamide, and in

some cases less), but that's irrelevent with respect to the safety

and efficacy of Nicomide.

He's snail mailing me data supporting the anti-inflammatory

properties of nicomide and topical use of niacinamide. I'll share

with the group what I learn. For now, I've decided to wait until I

see the studies; it concerns me that I haven't found any studies on

my own, and that the company can't articulate the strengths of their

product to someone very open to hearing them, but who asks pointed

questions rather than just believing the seductive jive.

Marjorie

Marjorie Lazoff, MD

> For Niacinamide to work effeciently is it necessary to take Zinc

and

> Folic acid too?

>

> If so which sort of Zinc should be taken, Zinc, Zinc Gluconate or

> Zinc Picolinate? Also how many mg's per day?

>

> What strength Folic acid should be taken daily?

>

> Many thanks

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