Guest guest Posted May 31, 2002 Report Share Posted May 31, 2002 Jennette, my understanding is that while initial studies in the late 1980s - early 1990s appeared hopeful, more recent work didn't substantiate the original claims, and despite aggressive advertising campaigns the public hasn't embraced the commercial preparations. So it doesn't appear to be as effective as a gentle exfoliant and/or improve cell turnover as first thought, but I believe it's as safe as originally proposed. I tried it (the Almay version) about a year ago. It made my skin burn (gee, there's a shocker! ) without providing any overt improvement to its appearance. Marjorie Marjorie Lazoff, MD > Has anyone heard of the product Kinerase? A lady I know has cea and swears by this stuff. > > Here is some info from their website....Any feedback would be appreciated.. > > Jennette > > Today, you have more choices than ever for helping reduce fine lines and wrinkles. But if you use topical retinoids, you may be trading wrinkles, blotches, and dryness for burning, redness, and peeling. 1 > Now, thanks to the development of KineraseTM with 0.1% N6- furfuryladenine, you have the ability to help reverse the signs of photoaging with virtually no skin irritation. > > > Looking Younger...Naturally. > Furfuryladenine is a natural plant growth factor that retards the aging process in plants. Cut leaves dipped in a solution containing furfuryladenine will remain green, while untreated leaves turn brown. Studies have shown furfuryladenine to have a similar effect in vitro on human skin cells, helping to slow and reverse alterations that naturally occur in the cell-aging process.2 > > > Scientifically Proven Results. > In clinical studies conducted by a dermatology department at the University of California, Irvine, KineraseTM was shown to help improve the signs of photoaging. After 24 weeks of treatment, physicians saw improvement in 100% of kinerase patients. Improvement was seen in roughness, blotchiness, and fine wrinkles.3 > > > KineraseTM Leaves Skin With a Smoother Look and Feel. > KineraseTM provides moisturizing qualities that outshine and outlast other moisturizing products you may be using. While some of these products may temporarily lessen the appearance of fine lines through improved hydration, that effect disappears a few hours after application. Kinerase enables the skin to retain more moisture, leaving it with a softer, smoother feel. > > > KineraseTM is not an Acid and Won't Burn Like One. > Unlike many other skin care products, KineraseTM is non- acidic and won't burn or irritate your skin. In fact, patients using Kinerase in clinical studies experienced virtually no side effects. > > > No Drug or Product Interactions. > KineraseTM has no known interactions with drugs or other products. And because there is virtually no irritation, you can use Kinerase in the morning before you apply makeup, in the daytime along with sunscreen, or with other appearance-enhancing products in the evening before bedtime. > > > A Sunny Day for Antiaging. > KineraseTM causes no increase in photosensitivity - a condition common among antiphotoaging therapies and characterized by burning, itching, and peeling with sun exposure. Since sun avoidance is recommended in any skin care program, a sunscreen with an SPF of 15 or higher should be used. With Kinerase, you're free to carry on your normal daily activities without additional sun restrictions. > > > Ask Your Skin Care Specialist. > If you're concerned about fine wrinkles and aging, or have had problems with your current skin therapies, ask your skin care specialist about KineraseTM. > > > References > 1. Green LJ, McCormick A, Weinstein GD. Photoaging and the skin. Dermatol Clin. 1993;11:97-105. > 2. Rattan SI, BF. Kinetin delays the onset of aging characteristics in human fibroblasts. Biochem Biophys Res Commun. 1994;201:665-672. > > 3. Data on file, ICN Pharmaceuticals, Inc. > > 4. Weinstein GD, Nigra TP, Pochi PE. Topical tretinon for treatment of photodamaged skin. Arch Dermatol. 1991;127:656-665. > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 31, 2002 Report Share Posted May 31, 2002 >> it doesn't appear to be as effective as a gentle exfoliant and/or > improve cell turnover as first thought, but I believe it's as safe as originally proposed. I tried it (the Almay version) about a year ago. It made my skin burn I would add, though, Jeanette, that in my opinion the Almay version was in no way like the real thing. In fact if you look at the ingredients on the Almay products, it doesn't even mention the plant factor " furfuryladenin " The Almay " Kinetin " also burned my face, but the actual Kinerase that I had previously used was very good and soothing---not too greasy, but moisturizing. I used for several months until my face decided to get really nasty. Now, almost nothing suits it. I have thought about going back to it, though. I believe it helped with the crows feet and baggy eyes. René Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 31, 2002 Report Share Posted May 31, 2002 >> it doesn't appear to be as effective as a gentle exfoliant and/or > improve cell turnover as first thought, but I believe it's as safe as originally proposed. I tried it (the Almay version) about a year ago. It made my skin burn I would add, though, Jeanette, that in my opinion the Almay version was in no way like the real thing. In fact if you look at the ingredients on the Almay products, it doesn't even mention the plant factor " furfuryladenin " The Almay " Kinetin " also burned my face, but the actual Kinerase that I had previously used was very good and soothing---not too greasy, but moisturizing. I used for several months until my face decided to get really nasty. Now, almost nothing suits it. I have thought about going back to it, though. I believe it helped with the crows feet and baggy eyes. René Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 31, 2002 Report Share Posted May 31, 2002 >> it doesn't appear to be as effective as a gentle exfoliant and/or > improve cell turnover as first thought, but I believe it's as safe as originally proposed. I tried it (the Almay version) about a year ago. It made my skin burn I would add, though, Jeanette, that in my opinion the Almay version was in no way like the real thing. In fact if you look at the ingredients on the Almay products, it doesn't even mention the plant factor " furfuryladenin " The Almay " Kinetin " also burned my face, but the actual Kinerase that I had previously used was very good and soothing---not too greasy, but moisturizing. I used for several months until my face decided to get really nasty. Now, almost nothing suits it. I have thought about going back to it, though. I believe it helped with the crows feet and baggy eyes. René Quote Link to comment Share on other sites More sharing options...
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