RE: Nicomide, B3, Niacinamide

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Additional from HealthWell:

Drug Interactions Summary for Vitamin B3:

Here is a list of medications that may interact with vitamin B3. It is

recommended you discuss the use of vitamin B3 and your current medication(s)

with your doctor or pharmacist.

http://www.healthwell.com/healthnotes/Supp/Drugix/Vitamin_B3.cfm

Also:

Are there any side effects or interactions?

Niacinamide is almost always safe to take, though rare liver problems have

occurred at amounts in excess of 1,000 mg per day. Niacin, in amounts as low

as 50-100 mg, may cause flushing, headache, and stomachache in some people.

Doctors sometimes prescribe very high amounts of niacin (as much as 3,000 mg

per day or more) for certain health problems. These large amounts can cause

liver damage, diabetes, gastritis, damage to eyes, and elevated blood levels

of uric acid (which can cause gout), and should never be taken without

consulting a doctor.

Niacinamide taken in combination with the antibiotics tetracycline or

minocycline has produced beneficial effects in individuals with bullous

pemphigoid, a benign, autoimmune blistering condition of the skin.

The inositol hexaniacinate form of niacin has not been linked with the side

effects associated with niacin supplementation. In a group of people being

treated alternatively with niacin and inositol hexaniacinate for skin

problems, niacin supplementation (50-100 mg per day) was associated with

numerous side effects, including skin flushing, nausea, vomiting and

agitation.8 In contrast, people taking inositol hexaniacinate experienced no

complaints whatsoever, even at amounts two to five times higher than the

previously used amounts of niacin. However, the amount of research studying

the safety of inositol hexaniacinate remains quite limited. Therefore,

people taking this supplement in large amounts (2,000 mg per day or more)

should be under the care of a doctor.

Vitamin B3 works with vitamin B1 and vitamin B2 to release energy from

carbohydrates. Therefore, these vitamins are often taken together in a

B-complex or multivitamin supplement (although most B3 research uses niacin

or niacinamide by itself).