Re: Nicomide Question For Marjorie

[Guest guest]

> I'm a bit confused by your most recent post about talking to the

> representative for Nicomide. To be a prescription drug, doesn't

> Nicomide have to go through the FDA clinical trial process (ie: be

> clinically proven to be effective and safe)? If so, aren't these

> studies available to the public?

I know, englishvet, I'm confused too -- I don't know why I can't

locate the studies. I'm no Medline maven , but I should have

picked up something.

It may be that drugs with folic acid > 1 mg automatically require

prescription because of known potential health hazards, while the

product itself isn't subject to FDA-required research.

Another thing I don't understand: each tablet only contains 500 mcg.

I don't know, but could Siruis *want* their formulation to be

prescription only, did they go out of their way for some commercial

benefit/reasons?

In the last post I said the source of information was from Drugdex --

I rechecked and I was wrong, it was from the Physician's Desk

Reference; the electronic drug database I consult searches multiple

references at one time but presents them in very similar formats.

It turns out that Drugdex (a huge proprietary pharmaceutical

database) has nothing on Nicomide, which is curious in and of itself.

That's important because PDR reprints the FDA-required insert

information, so for approved drugs we usually get a full though not

very insightful presentation. But the PDR doesn't have the usual

profile for Nicomide as is typical for other prescription drugs, just

a short monograph. So there may be some exception for vitamins. I

don't know.

We'll see what they send me, and go from there.

> I have just started taking Nicomide, but am only taking one tab a

day

> (recommended dosage is one or two tabs a day). Too early yet to make

> any comments, but will keep you informed. I am also using a 4%

> niacinamide topical spray twice daily.

Why did you start them both at the same time? If you face gets

better, how will you know which made the difference?

Please keep us posted. My best anti-inflammatory thoughts from across

the Atlantic!

Marjorie

Marjorie Lazoff, MD

> I'm a bit confused by your most recent post about talking to the

> representative for Nicomide. To be a prescription drug, doesn't

> Nicomide have to go through the FDA clinical trial process (ie: be

> clinically proven to be effective and safe)? If so, aren't these

> studies available to the public?

>

> I am often confused by the FDA. I have first hand experience of

animal

> drugs and vaccines that presumably went through their reqirements

and

> are absolutely useless. For instance, there is an FDA approved

vaccine

> for Lyme disease in dogs.......Lyme disease has yet to be induced in

> dogs in a single independent study! Few clinicians believe it

exists.

>

> I have just started taking Nicomide, but am only taking one tab a

day

> (recommended dosage is one or two tabs a day). Too early yet to make

> any comments, but will keep you informed. I am also using a 4%

> niacinamide topical spray twice daily.

[Guest guest]

> I'm a bit confused by your most recent post about talking to the

> representative for Nicomide. To be a prescription drug, doesn't

> Nicomide have to go through the FDA clinical trial process (ie: be

> clinically proven to be effective and safe)? If so, aren't these

> studies available to the public?

I know, englishvet, I'm confused too -- I don't know why I can't

locate the studies. I'm no Medline maven , but I should have

picked up something.

It may be that drugs with folic acid > 1 mg automatically require

prescription because of known potential health hazards, while the

product itself isn't subject to FDA-required research.

Another thing I don't understand: each tablet only contains 500 mcg.

I don't know, but could Siruis *want* their formulation to be

prescription only, did they go out of their way for some commercial

benefit/reasons?

In the last post I said the source of information was from Drugdex --

I rechecked and I was wrong, it was from the Physician's Desk

Reference; the electronic drug database I consult searches multiple

references at one time but presents them in very similar formats.

It turns out that Drugdex (a huge proprietary pharmaceutical

database) has nothing on Nicomide, which is curious in and of itself.

That's important because PDR reprints the FDA-required insert

information, so for approved drugs we usually get a full though not

very insightful presentation. But the PDR doesn't have the usual

profile for Nicomide as is typical for other prescription drugs, just

a short monograph. So there may be some exception for vitamins. I

don't know.

We'll see what they send me, and go from there.

> I have just started taking Nicomide, but am only taking one tab a

day

> (recommended dosage is one or two tabs a day). Too early yet to make

> any comments, but will keep you informed. I am also using a 4%

> niacinamide topical spray twice daily.

Why did you start them both at the same time? If you face gets

better, how will you know which made the difference?

Please keep us posted. My best anti-inflammatory thoughts from across

the Atlantic!

Marjorie

Marjorie Lazoff, MD

> I'm a bit confused by your most recent post about talking to the

> representative for Nicomide. To be a prescription drug, doesn't

> Nicomide have to go through the FDA clinical trial process (ie: be

> clinically proven to be effective and safe)? If so, aren't these

> studies available to the public?

>

> I am often confused by the FDA. I have first hand experience of

animal

> drugs and vaccines that presumably went through their reqirements

and

> are absolutely useless. For instance, there is an FDA approved

vaccine

> for Lyme disease in dogs.......Lyme disease has yet to be induced in

> dogs in a single independent study! Few clinicians believe it

exists.

>

> I have just started taking Nicomide, but am only taking one tab a

day

> (recommended dosage is one or two tabs a day). Too early yet to make

> any comments, but will keep you informed. I am also using a 4%

> niacinamide topical spray twice daily.

[Guest guest]

> I'm a bit confused by your most recent post about talking to the

> representative for Nicomide. To be a prescription drug, doesn't

> Nicomide have to go through the FDA clinical trial process (ie: be

> clinically proven to be effective and safe)? If so, aren't these

> studies available to the public?

I know, englishvet, I'm confused too -- I don't know why I can't

locate the studies. I'm no Medline maven , but I should have

picked up something.

It may be that drugs with folic acid > 1 mg automatically require

prescription because of known potential health hazards, while the

product itself isn't subject to FDA-required research.

Another thing I don't understand: each tablet only contains 500 mcg.

I don't know, but could Siruis *want* their formulation to be

prescription only, did they go out of their way for some commercial

benefit/reasons?

In the last post I said the source of information was from Drugdex --

I rechecked and I was wrong, it was from the Physician's Desk

Reference; the electronic drug database I consult searches multiple

references at one time but presents them in very similar formats.

It turns out that Drugdex (a huge proprietary pharmaceutical

database) has nothing on Nicomide, which is curious in and of itself.

That's important because PDR reprints the FDA-required insert

information, so for approved drugs we usually get a full though not

very insightful presentation. But the PDR doesn't have the usual

profile for Nicomide as is typical for other prescription drugs, just

a short monograph. So there may be some exception for vitamins. I

don't know.

We'll see what they send me, and go from there.

> I have just started taking Nicomide, but am only taking one tab a

day

> (recommended dosage is one or two tabs a day). Too early yet to make

> any comments, but will keep you informed. I am also using a 4%

> niacinamide topical spray twice daily.

Why did you start them both at the same time? If you face gets

better, how will you know which made the difference?

Please keep us posted. My best anti-inflammatory thoughts from across

the Atlantic!

Marjorie

Marjorie Lazoff, MD

> I'm a bit confused by your most recent post about talking to the

> representative for Nicomide. To be a prescription drug, doesn't

> Nicomide have to go through the FDA clinical trial process (ie: be

> clinically proven to be effective and safe)? If so, aren't these

> studies available to the public?

>

> I am often confused by the FDA. I have first hand experience of

animal

> drugs and vaccines that presumably went through their reqirements

and

> are absolutely useless. For instance, there is an FDA approved

vaccine

> for Lyme disease in dogs.......Lyme disease has yet to be induced in

> dogs in a single independent study! Few clinicians believe it

exists.

>

> I have just started taking Nicomide, but am only taking one tab a

day

> (recommended dosage is one or two tabs a day). Too early yet to make

> any comments, but will keep you informed. I am also using a 4%

> niacinamide topical spray twice daily.

[Guest guest]

Once again: Thank you for taking the time to answer my questions.

First, if my face improves using these two products together I really

don't care if it's due to the combination or just one product alone:

I'll continue to use both regardless (unless I find proof that one of

them is useless). They are cheap and pretty much harmless as far as my

research indicates.

Second: I am English, and I am a veterinarian, but I live in Dallas, TX.

[Guest guest]

> Second: I am English, and I am a veterinarian, but I live in

> Dallas, TX.

So you wash your BBQ and hickory-smoked beans down with a spot of

tea, I suppose.

I'll redirect the anti-inflammatory best wishes accordingly.

Marjorie