Guest guest Posted May 25, 2002 Report Share Posted May 25, 2002 Yes please, do let me know when the product will become available, I am in canada. Re: Repost from Dr. Pilcher > Dr. Pilcher, > > Please let us know when the product will be available and where we > can buy it. > > Thanks, > Matija > > > > > I would urge you to look at the degree of improvement between > control > > and treated groups rather than looking solely at numbers of those > > that improved. We fully agree that the control group did show > > improvement- in fact, it simply bolsters our confidence that we > have > > a highly moisturizing lotion that aids in the treatment of symptoms > > such as desquamation. We have seen this consistently in our eczema > > studies as well. Your point is well taken about dermal vs. > epidermal > > inflammation. We have found in our Franz cell analyses that we are > > able to obtain biologically active amounts of compound in the > dermis > > of human skin. So I personally believe that any effects in the > > epidermis will also be seen in the dermis as well. > > > > If there were no limitations on claims why would we claim to have a > > cure if it didn't cure rosacea? I hope that you see we are not > making > > those types of claims. In fact, all we have said since the firs > post > > is that it helps in improving symptoms. I don't want to sound > > defensive and am truly trying to keep an open mind. Please forgive > me > > if I feel just a little grilled over the coals J. > > > > The sunscreen effect you refer to is due to the molecular structure > > of Quadrinone. It was discovered in one of our initial UV studies > > that it had the ability to absorb UVR. In the very first clinical > > study performed by Cutanix patients were pre-dosed with the lotion > > prior to UV exposure. Naturally, the data came back incredibly > > positive and we were extremely pleased. Then we decided to test for > > UV absorbing capacity and indeed Quadrinone in a 5% lotion had an > spf > > of 8-9. We have since looked at 2% and 1% lotions and for those the > > spf is around 3-4 and 1-2, respectively. In all of our subsequent > > clinical studies we have post-dosed the subjects with control or > > active lotions after UV treatment to prevent skewing our data with > > the natural sunscreen characteristics of the molecule. In those > > studies Quadrinone effectively inhibit UV-induced erythema. > > > > It seems as though we are bound to disagree on much and I hope that > > none of our debate has been taken personally. Although, I have to > > admit that it has been hard for me at times. All that our company > > asks is that you give us a shot and see if the product works in > your > > case. Cheers to all in this group- you are why I do what I do. > > > > Pilcher > > > -- > Please read the list highlights before posting to the whole group (http://rosacea.ii.net/toc.html). Your post will be delayed if you don't give a meaningful subject or trim your reply text. You must change the subject when replying to a digest ! > > See http://www.drnase.com for info on his recently published book. > > To leave the list send an email to rosacea-support-unsubscribe > > Quote Link to comment Share on other sites More sharing options...
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