Re: Cutanix Dramatic Relief Lotion I take full responsibility.

[Guest guest]

Hi Rory,

You know, I never received any emails from you. I wonder what

happened. Please don't think I ignored you. I would have been glad to

post this information for you because I remember posting about

Cutanix a few months ago after I read about it on the bfs board. Dr.

Sy's ZincO was tested by people in our group and that has worked

wonders for many of us. It hasn't been tested like a drug.

However, I'm glad you had Adam post the information on this, and it's

great that this product works wonders for you. Did you happen to get

the all the ingredients of this product by chance? Thank you so much

for following up on this. I feel bad because you live all the way in

Ireland and I live 40 miles away from the Cutanix company in Santa

Clara, California. I could drive there. Anyway, don't hesitate to

contact me personally if you have anymore information like this. If I

don't answer, please page me at the board.

Take care,

Matija

> I would just like to clear up a few things that have been said

> by Dr Lazoff on the launch of this product in a few weeks.

> This is my story on how I stumbled across this product.I dont

> know if any of you have ever heard of Melanx.It was developed

> by Dr Fuller in the university of Illinois as the future

> of tanning without sun exposure.I emailed the University to ask

> Dr Fuller when this product will be available and also if this

> will be a product that could be used on sensitive rosacea skin.

> I was amazed that I got a response.Dr fuller said that it wont

> be a harsh product and should have no problem with sensitive skin.

> He then went on to tell me that he has also developed an

> anti-inflammatory lotion which he has given to some people with

> rosacea and has had a great response.He said that he has sent it

> to the lab(Cutanix) for testing.I then rang Cutanix and was lucky

> enough to get through to the CEO Mr Ingals.I was mainly

> interested in finding out about Melanx but Mr Ingals was nice

> enough to send me a bottle of CX 452 to test out on my rosacea

> as long as I kept him informed.

>

> Two days on CX452 my skin was totally clear of seborrheic

dermatitis.

> I mean totally.No flakes,itching or inflammation associated with

> seb.derm.Unfortunately I didnt notice any difference to my cea

> and I reported this to Mr Ingals a few weeks later.Mr ingals said

that

> they were having excellent results on seb derm and eczema but

minimal

> results with cea.All of this has been discussed on the BFS forum

> in january.I knew that the product was going to be launched in the

> middle of this year so a couple of weeks ago members of the BFS

forum

> asked me to find out more.So I did.Mr Ingals then informed me that

> they had increased the active ingredient from 0.5%(which was the one

> that I used) to 1% for the IRB trial.He said that they were very

happy

> at the improved results for cea.He summarised the results of the

> IRB trial in one paragraph and I asked him if I could post his email

> to some forums that would be interested.Obviously Mr Ingals agreed

> (its all advertising isnt it?)and sent me a summary of the IRB

trial.

>

> I can assure everyone on this forum that I have no connection with

> Cutanix.I am just a bar manager from the west of Ireland.I have been

> a member of this forum in the past but I had a little run in with

> Mr Pascoe.Matija posted about Cutanix a few months ago about what

> was being said on the BFS forum.So I emailed the IRB trial to Matija

> twice last week but without response.Adam was kind enough to do it

for

> me since we are both members of the seb.derm group.I hope this

clears

> up the fact that there is no one from Cutanix trying to slip

anything

> into this forum.I am the one who has slipped it in for them and I

> believe that this will help some of you.

>

> Rory

[Guest guest]

Rory, I appreciate your enthusiasm and willingness to share your

personal experiences with others.

Still in my inquisitive mode , could you clarify the relationships

among Dr. Fuller, the University of Illinois, the Melanx Company, and

the Cutanix Company? I ask because it's hard to believe that a

university researcher would send his discovery to a commercial

company " for testing. " (If anything, it's the other way around.) I

would assume that Dr. Fuller is either under contract with Cutanix,

or sold his discovery to Cutanix. I assume he had/has a similiar

relationship with Melanx as with Cutanix, both of which appear to be

small, privately held, for-profit companies, presumably unrelated to

one other. But I'm just assuming -- I don't know how these things

work in a university setting. Can you clarify this?

Issues of efficacy aside, safety is a concern. I took away from

reading the press release that this product's anti-inflammatory

properties are similar to steroids, but safer. How does anyone know

this? Even with the best of intentions, safety can be subtle. For

example, topical steroids were originally thought to be far safer

than oral steroids, until problems with chronic use became evident

(as some on this board can attest).

Thanks.

Marjorie

Marjorie Lazoff, MD

> I would just like to clear up a few things that have been said

> by Dr Lazoff on the launch of this product in a few weeks.

> This is my story on how I stumbled across this product.I dont

> know if any of you have ever heard of Melanx.It was developed

> by Dr Fuller in the university of Illinois as the future

> of tanning without sun exposure.I emailed the University to ask

> Dr Fuller when this product will be available and also if this

> will be a product that could be used on sensitive rosacea skin.

> I was amazed that I got a response.Dr fuller said that it wont

> be a harsh product and should have no problem with sensitive skin.

> He then went on to tell me that he has also developed an

> anti-inflammatory lotion which he has given to some people with

> rosacea and has had a great response.He said that he has sent it

> to the lab(Cutanix) for testing.I then rang Cutanix and was lucky

> enough to get through to the CEO Mr Ingals.I was mainly

> interested in finding out about Melanx but Mr Ingals was nice

> enough to send me a bottle of CX 452 to test out on my rosacea

> as long as I kept him informed.

>

> Two days on CX452 my skin was totally clear of seborrheic

dermatitis.

> I mean totally.No flakes,itching or inflammation associated with

> seb.derm.Unfortunately I didnt notice any difference to my cea

> and I reported this to Mr Ingals a few weeks later.Mr ingals said

that

> they were having excellent results on seb derm and eczema but

minimal

> results with cea.All of this has been discussed on the BFS forum

> in january.I knew that the product was going to be launched in the

> middle of this year so a couple of weeks ago members of the BFS

forum

> asked me to find out more.So I did.Mr Ingals then informed me that

> they had increased the active ingredient from 0.5%(which was the one

> that I used) to 1% for the IRB trial.He said that they were very

happy

> at the improved results for cea.He summarised the results of the

> IRB trial in one paragraph and I asked him if I could post his email

> to some forums that would be interested.Obviously Mr Ingals agreed

> (its all advertising isnt it?)and sent me a summary of the IRB

trial.

>

> I can assure everyone on this forum that I have no connection with

> Cutanix.I am just a bar manager from the west of Ireland.I have been

> a member of this forum in the past but I had a little run in with

> Mr Pascoe.Matija posted about Cutanix a few months ago about what

> was being said on the BFS forum.So I emailed the IRB trial to Matija

> twice last week but without response.Adam was kind enough to do it

for

> me since we are both members of the seb.derm group.I hope this

clears

> up the fact that there is no one from Cutanix trying to slip

anything

> into this forum.I am the one who has slipped it in for them and I

> believe that this will help some of you.

>

> Rory

[Guest guest]

Rory, I appreciate your enthusiasm and willingness to share your

personal experiences with others.

Still in my inquisitive mode , could you clarify the relationships

among Dr. Fuller, the University of Illinois, the Melanx Company, and

the Cutanix Company? I ask because it's hard to believe that a

university researcher would send his discovery to a commercial

company " for testing. " (If anything, it's the other way around.) I

would assume that Dr. Fuller is either under contract with Cutanix,

or sold his discovery to Cutanix. I assume he had/has a similiar

relationship with Melanx as with Cutanix, both of which appear to be

small, privately held, for-profit companies, presumably unrelated to

one other. But I'm just assuming -- I don't know how these things

work in a university setting. Can you clarify this?

Issues of efficacy aside, safety is a concern. I took away from

reading the press release that this product's anti-inflammatory

properties are similar to steroids, but safer. How does anyone know

this? Even with the best of intentions, safety can be subtle. For

example, topical steroids were originally thought to be far safer

than oral steroids, until problems with chronic use became evident

(as some on this board can attest).

Thanks.

Marjorie

Marjorie Lazoff, MD

> I would just like to clear up a few things that have been said

> by Dr Lazoff on the launch of this product in a few weeks.

> This is my story on how I stumbled across this product.I dont

> know if any of you have ever heard of Melanx.It was developed

> by Dr Fuller in the university of Illinois as the future

> of tanning without sun exposure.I emailed the University to ask

> Dr Fuller when this product will be available and also if this

> will be a product that could be used on sensitive rosacea skin.

> I was amazed that I got a response.Dr fuller said that it wont

> be a harsh product and should have no problem with sensitive skin.

> He then went on to tell me that he has also developed an

> anti-inflammatory lotion which he has given to some people with

> rosacea and has had a great response.He said that he has sent it

> to the lab(Cutanix) for testing.I then rang Cutanix and was lucky

> enough to get through to the CEO Mr Ingals.I was mainly

> interested in finding out about Melanx but Mr Ingals was nice

> enough to send me a bottle of CX 452 to test out on my rosacea

> as long as I kept him informed.

>

> Two days on CX452 my skin was totally clear of seborrheic

dermatitis.

> I mean totally.No flakes,itching or inflammation associated with

> seb.derm.Unfortunately I didnt notice any difference to my cea

> and I reported this to Mr Ingals a few weeks later.Mr ingals said

that

> they were having excellent results on seb derm and eczema but

minimal

> results with cea.All of this has been discussed on the BFS forum

> in january.I knew that the product was going to be launched in the

> middle of this year so a couple of weeks ago members of the BFS

forum

> asked me to find out more.So I did.Mr Ingals then informed me that

> they had increased the active ingredient from 0.5%(which was the one

> that I used) to 1% for the IRB trial.He said that they were very

happy

> at the improved results for cea.He summarised the results of the

> IRB trial in one paragraph and I asked him if I could post his email

> to some forums that would be interested.Obviously Mr Ingals agreed

> (its all advertising isnt it?)and sent me a summary of the IRB

trial.

>

> I can assure everyone on this forum that I have no connection with

> Cutanix.I am just a bar manager from the west of Ireland.I have been

> a member of this forum in the past but I had a little run in with

> Mr Pascoe.Matija posted about Cutanix a few months ago about what

> was being said on the BFS forum.So I emailed the IRB trial to Matija

> twice last week but without response.Adam was kind enough to do it

for

> me since we are both members of the seb.derm group.I hope this

clears

> up the fact that there is no one from Cutanix trying to slip

anything

> into this forum.I am the one who has slipped it in for them and I

> believe that this will help some of you.

>

> Rory

[Guest guest]

> Marjorie,your concerns are appreciated and justified.But

> we could also point these concerns at other topical immune

> modulaters like Protopic and Elidel.

I agree with you completely, Rory. Although I haven't taken a close

at those studies -- who funded them and whether they are well

designed/executed -- I would have identical concerns.

> None of us know what

> they may discover about these ten years down the road.

True. But I draw a distinction between what we can expect from a

study, and what we can expect from a product. I try not to confuse

the two (which is hard, in threads like this). One would think they

are related -- and usually there are, but not inevitably.

> But we

> are desperate people with a desperate condition

Whether true or not, desperation is no reason to victimize ourselves.

Do you know what I mean?

> and I will

> not wait that long before I feel it is safe to use these

> topicals.

> I dont think any company could afford to test a

> product that long before releasing it.Protopic and Elidel

> have a long list of possible side effects and cautions but

> I am in my 30s and I am not going to wait until my 40s before

> I feel it might be safe to use them.

That's your choice, that's all our choices. My point is this: the

more accurate information we have available to make an informed

decision at any point in time, the better off we are. We're never

going to have unlimited, totally accurate information -- but I don't

believe that means we should just accept poor research or veiled

marketing without question, or throw our hands up entirely because

this stuff is intimidating or difficult to appreciate at first scan.

Marjorie

Marjorie Lazoff, MD