Antibiotics - Switching from Minocycline to Zithromax

[Guest guest]

I told the nurse at my derm's office that I want to be off

antibiotics by my birthday (July 27th). She said thats fine, but

first she wants me to switch from Minocycline (100mgs 2x daily)

to Zithromax. (250mgs 3x weekly) I told her about Photoderm and

how I cant do anything to make myself flush for a while. She

said it shouldnt be a problem. But I've been screwed over by a

doctor/derm's complete lack of knowledge way more than once now,

and don't wanna just take her word for it. Does anyone here know

if switching from Minocycline to Zithromax will cause a flare? I

flared real bad when I tried to quit my Minocycline cold-turkey,

but I guess the theory is if I switch from one antibiotic to the

other I should be ok? Any thoughts?

Adam

[Guest guest]

Sorry for replying to my own message but I had a little brain fart for a

second. The first line is supposed to say there is no problem with

Minocycline together with Photoderm. Sorry. Hopefully that makes more

sense.

Antibiotics - Switching from Minocycline to Zithromax

> >

> > I told the nurse at my derm's office that I want to be off

> > antibiotics by my birthday (July 27th). She said thats fine, but

> > first she wants me to switch from Minocycline (100mgs 2x daily)

> > to Zithromax. (250mgs 3x weekly) I told her about Photoderm and

> > how I cant do anything to make myself flush for a while. She

> > said it shouldnt be a problem. But I've been screwed over by a

> > doctor/derm's complete lack of knowledge way more than once now,

> > and don't wanna just take her word for it. Does anyone here know

> > if switching from Minocycline to Zithromax will cause a flare? I

> > flared real bad when I tried to quit my Minocycline cold-turkey,

> > but I guess the theory is if I switch from one antibiotic to the

> > other I should be ok? Any thoughts?

> >

> > Adam

> >

> >

> >

> >

> > --

> > Please read the list highlights before posting to the whole group

> (http://rosacea.ii.net/toc.html). Your post will be delayed if you don't

> give a meaningful subject or trim your reply text. You must change the

> subject when replying to a digest !

> >

> > See http://www.drnase.com for info on his recently published book.

> >

> > To leave the list send an email to

> rosacea-support-unsubscribe

> >

> >

[Guest guest]

Sorry for replying to my own message but I had a little brain fart for a

second. The first line is supposed to say there is no problem with

Minocycline together with Photoderm. Sorry. Hopefully that makes more

sense.

Antibiotics - Switching from Minocycline to Zithromax

> >

> > I told the nurse at my derm's office that I want to be off

> > antibiotics by my birthday (July 27th). She said thats fine, but

> > first she wants me to switch from Minocycline (100mgs 2x daily)

> > to Zithromax. (250mgs 3x weekly) I told her about Photoderm and

> > how I cant do anything to make myself flush for a while. She

> > said it shouldnt be a problem. But I've been screwed over by a

> > doctor/derm's complete lack of knowledge way more than once now,

> > and don't wanna just take her word for it. Does anyone here know

> > if switching from Minocycline to Zithromax will cause a flare? I

> > flared real bad when I tried to quit my Minocycline cold-turkey,

> > but I guess the theory is if I switch from one antibiotic to the

> > other I should be ok? Any thoughts?

> >

> > Adam

> >

> >

> >

> >

> > --

> > Please read the list highlights before posting to the whole group

> (http://rosacea.ii.net/toc.html). Your post will be delayed if you don't

> give a meaningful subject or trim your reply text. You must change the

> subject when replying to a digest !

> >

> > See http://www.drnase.com for info on his recently published book.

> >

> > To leave the list send an email to

> rosacea-support-unsubscribe

> >

> >

[Guest guest]

Adam, I wasn't aware that antibiotics impacted on flushing one way or

the other. My understanding is that the redness that responds to

antibiotics is from inflammation, not vascular flushing.

But a flare is different than a flush. Your rosacea may flare with

changes in antibiotics if they are having an anti-inflammatory

effect, if underlying inflammation is being masked by the present

antibiotics. On the other hand, without ongoing inflammation you may

enjoy a remission without antibiotics, or perhaps the antibiotics may

be doing nothing for you.

Adam, I don't have a good sense what's happening with your skin to

help advise you in any way, and my confusion is not the kind that

more information from you will help. Also, I can't know how much your

psychological nature impacts on all this. I wouldn't think that

deciding by yourself whether to go on/off antibiotics while still

dealing with phototherapy effects is likely to have a good outcome.

Will you be twenty, or still a teenager?

Marjorie

Marjorie Lazoff,, MD

> I told the nurse at my derm's office that I want to be off

> antibiotics by my birthday (July 27th). She said thats fine, but

> first she wants me to switch from Minocycline (100mgs 2x daily)

> to Zithromax. (250mgs 3x weekly) I told her about Photoderm and

> how I cant do anything to make myself flush for a while. She

> said it shouldnt be a problem. But I've been screwed over by a

> doctor/derm's complete lack of knowledge way more than once now,

> and don't wanna just take her word for it. Does anyone here know

> if switching from Minocycline to Zithromax will cause a flare? I

> flared real bad when I tried to quit my Minocycline cold-turkey,

> but I guess the theory is if I switch from one antibiotic to the

> other I should be ok? Any thoughts?

>

> Adam

>

>

>

[Guest guest]

Adam, I wasn't aware that antibiotics impacted on flushing one way or

the other. My understanding is that the redness that responds to

antibiotics is from inflammation, not vascular flushing.

But a flare is different than a flush. Your rosacea may flare with

changes in antibiotics if they are having an anti-inflammatory

effect, if underlying inflammation is being masked by the present

antibiotics. On the other hand, without ongoing inflammation you may

enjoy a remission without antibiotics, or perhaps the antibiotics may

be doing nothing for you.

Adam, I don't have a good sense what's happening with your skin to

help advise you in any way, and my confusion is not the kind that

more information from you will help. Also, I can't know how much your

psychological nature impacts on all this. I wouldn't think that

deciding by yourself whether to go on/off antibiotics while still

dealing with phototherapy effects is likely to have a good outcome.

Will you be twenty, or still a teenager?

Marjorie

Marjorie Lazoff,, MD

> I told the nurse at my derm's office that I want to be off

> antibiotics by my birthday (July 27th). She said thats fine, but

> first she wants me to switch from Minocycline (100mgs 2x daily)

> to Zithromax. (250mgs 3x weekly) I told her about Photoderm and

> how I cant do anything to make myself flush for a while. She

> said it shouldnt be a problem. But I've been screwed over by a

> doctor/derm's complete lack of knowledge way more than once now,

> and don't wanna just take her word for it. Does anyone here know

> if switching from Minocycline to Zithromax will cause a flare? I

> flared real bad when I tried to quit my Minocycline cold-turkey,

> but I guess the theory is if I switch from one antibiotic to the

> other I should be ok? Any thoughts?

>

> Adam

>

>

>

[Guest guest]

Adam, I wasn't aware that antibiotics impacted on flushing one way or

the other. My understanding is that the redness that responds to

antibiotics is from inflammation, not vascular flushing.

But a flare is different than a flush. Your rosacea may flare with

changes in antibiotics if they are having an anti-inflammatory

effect, if underlying inflammation is being masked by the present

antibiotics. On the other hand, without ongoing inflammation you may

enjoy a remission without antibiotics, or perhaps the antibiotics may

be doing nothing for you.

Adam, I don't have a good sense what's happening with your skin to

help advise you in any way, and my confusion is not the kind that

more information from you will help. Also, I can't know how much your

psychological nature impacts on all this. I wouldn't think that

deciding by yourself whether to go on/off antibiotics while still

dealing with phototherapy effects is likely to have a good outcome.

Will you be twenty, or still a teenager?

Marjorie

Marjorie Lazoff,, MD

> I told the nurse at my derm's office that I want to be off

> antibiotics by my birthday (July 27th). She said thats fine, but

> first she wants me to switch from Minocycline (100mgs 2x daily)

> to Zithromax. (250mgs 3x weekly) I told her about Photoderm and

> how I cant do anything to make myself flush for a while. She

> said it shouldnt be a problem. But I've been screwed over by a

> doctor/derm's complete lack of knowledge way more than once now,

> and don't wanna just take her word for it. Does anyone here know

> if switching from Minocycline to Zithromax will cause a flare? I

> flared real bad when I tried to quit my Minocycline cold-turkey,

> but I guess the theory is if I switch from one antibiotic to the

> other I should be ok? Any thoughts?

>

> Adam

>

>

>

[Guest guest]

Thanks. All I remember from the Minocycline withdrawl is that I was very

red and broken out and swollen. If the flushing itself is unaffected and

its just inflammation making things look and feel worse, then theoretically,

switching antibiotics shouldnt have much of a lasting impact on Photoderm.

I am switching at the request of my new dermatologist but wanted to decide

for myself if this was the right time (even tho the nurse told me it was).

I guess I don't have much to lose tho, my skin is a real mess right now

anyway Do you (or anyone else on this board) know how long it'll take

for the Zithromax to kick in? The derm told me since I'm switching from

Minocycline to Zithromax (rather than starting from scratch) it shouldn't

take as long.. I have my final Photoderm Treatment set up for May 24th and

it'd make me feel better to know the Zithromax would be working by then.

I'll be twenty in July, but I am sure I will still act like a teenager

Adam

Re: Antibiotics - Switching from Minocycline to Zithromax

> Adam, I wasn't aware that antibiotics impacted on flushing one way or

> the other. My understanding is that the redness that responds to

> antibiotics is from inflammation, not vascular flushing.

>

> But a flare is different than a flush. Your rosacea may flare with

> changes in antibiotics if they are having an anti-inflammatory

> effect, if underlying inflammation is being masked by the present

> antibiotics. On the other hand, without ongoing inflammation you may

> enjoy a remission without antibiotics, or perhaps the antibiotics may

> be doing nothing for you.

>

> Adam, I don't have a good sense what's happening with your skin to

> help advise you in any way, and my confusion is not the kind that

> more information from you will help. Also, I can't know how much your

> psychological nature impacts on all this. I wouldn't think that

> deciding by yourself whether to go on/off antibiotics while still

> dealing with phototherapy effects is likely to have a good outcome.

>

> Will you be twenty, or still a teenager?

>

>

> Marjorie

>

> Marjorie Lazoff,, MD

>

>

>

> > I told the nurse at my derm's office that I want to be off

> > antibiotics by my birthday (July 27th). She said thats fine, but

> > first she wants me to switch from Minocycline (100mgs 2x daily)

> > to Zithromax. (250mgs 3x weekly) I told her about Photoderm and

> > how I cant do anything to make myself flush for a while. She

> > said it shouldnt be a problem. But I've been screwed over by a

> > doctor/derm's complete lack of knowledge way more than once now,

> > and don't wanna just take her word for it. Does anyone here know

> > if switching from Minocycline to Zithromax will cause a flare? I

> > flared real bad when I tried to quit my Minocycline cold-turkey,

> > but I guess the theory is if I switch from one antibiotic to the

> > other I should be ok? Any thoughts?

> >

> > Adam

> >

> >

> >

[Guest guest]

Thanks. All I remember from the Minocycline withdrawl is that I was very

red and broken out and swollen. If the flushing itself is unaffected and

its just inflammation making things look and feel worse, then theoretically,

switching antibiotics shouldnt have much of a lasting impact on Photoderm.

I am switching at the request of my new dermatologist but wanted to decide

for myself if this was the right time (even tho the nurse told me it was).

I guess I don't have much to lose tho, my skin is a real mess right now

anyway Do you (or anyone else on this board) know how long it'll take

for the Zithromax to kick in? The derm told me since I'm switching from

Minocycline to Zithromax (rather than starting from scratch) it shouldn't

take as long.. I have my final Photoderm Treatment set up for May 24th and

it'd make me feel better to know the Zithromax would be working by then.

I'll be twenty in July, but I am sure I will still act like a teenager

Adam

Re: Antibiotics - Switching from Minocycline to Zithromax

> Adam, I wasn't aware that antibiotics impacted on flushing one way or

> the other. My understanding is that the redness that responds to

> antibiotics is from inflammation, not vascular flushing.

>

> But a flare is different than a flush. Your rosacea may flare with

> changes in antibiotics if they are having an anti-inflammatory

> effect, if underlying inflammation is being masked by the present

> antibiotics. On the other hand, without ongoing inflammation you may

> enjoy a remission without antibiotics, or perhaps the antibiotics may

> be doing nothing for you.

>

> Adam, I don't have a good sense what's happening with your skin to

> help advise you in any way, and my confusion is not the kind that

> more information from you will help. Also, I can't know how much your

> psychological nature impacts on all this. I wouldn't think that

> deciding by yourself whether to go on/off antibiotics while still

> dealing with phototherapy effects is likely to have a good outcome.

>

> Will you be twenty, or still a teenager?

>

>

> Marjorie

>

> Marjorie Lazoff,, MD

>

>

>

> > I told the nurse at my derm's office that I want to be off

> > antibiotics by my birthday (July 27th). She said thats fine, but

> > first she wants me to switch from Minocycline (100mgs 2x daily)

> > to Zithromax. (250mgs 3x weekly) I told her about Photoderm and

> > how I cant do anything to make myself flush for a while. She

> > said it shouldnt be a problem. But I've been screwed over by a

> > doctor/derm's complete lack of knowledge way more than once now,

> > and don't wanna just take her word for it. Does anyone here know

> > if switching from Minocycline to Zithromax will cause a flare? I

> > flared real bad when I tried to quit my Minocycline cold-turkey,

> > but I guess the theory is if I switch from one antibiotic to the

> > other I should be ok? Any thoughts?

> >

> > Adam

> >

> >

> >

[Guest guest]

Thanks. All I remember from the Minocycline withdrawl is that I was very

red and broken out and swollen. If the flushing itself is unaffected and

its just inflammation making things look and feel worse, then theoretically,

switching antibiotics shouldnt have much of a lasting impact on Photoderm.

I am switching at the request of my new dermatologist but wanted to decide

for myself if this was the right time (even tho the nurse told me it was).

I guess I don't have much to lose tho, my skin is a real mess right now

anyway Do you (or anyone else on this board) know how long it'll take

for the Zithromax to kick in? The derm told me since I'm switching from

Minocycline to Zithromax (rather than starting from scratch) it shouldn't

take as long.. I have my final Photoderm Treatment set up for May 24th and

it'd make me feel better to know the Zithromax would be working by then.

I'll be twenty in July, but I am sure I will still act like a teenager

Adam

Re: Antibiotics - Switching from Minocycline to Zithromax

> Adam, I wasn't aware that antibiotics impacted on flushing one way or

> the other. My understanding is that the redness that responds to

> antibiotics is from inflammation, not vascular flushing.

>

> But a flare is different than a flush. Your rosacea may flare with

> changes in antibiotics if they are having an anti-inflammatory

> effect, if underlying inflammation is being masked by the present

> antibiotics. On the other hand, without ongoing inflammation you may

> enjoy a remission without antibiotics, or perhaps the antibiotics may

> be doing nothing for you.

>

> Adam, I don't have a good sense what's happening with your skin to

> help advise you in any way, and my confusion is not the kind that

> more information from you will help. Also, I can't know how much your

> psychological nature impacts on all this. I wouldn't think that

> deciding by yourself whether to go on/off antibiotics while still

> dealing with phototherapy effects is likely to have a good outcome.

>

> Will you be twenty, or still a teenager?

>

>

> Marjorie

>

> Marjorie Lazoff,, MD

>

>

>

> > I told the nurse at my derm's office that I want to be off

> > antibiotics by my birthday (July 27th). She said thats fine, but

> > first she wants me to switch from Minocycline (100mgs 2x daily)

> > to Zithromax. (250mgs 3x weekly) I told her about Photoderm and

> > how I cant do anything to make myself flush for a while. She

> > said it shouldnt be a problem. But I've been screwed over by a

> > doctor/derm's complete lack of knowledge way more than once now,

> > and don't wanna just take her word for it. Does anyone here know

> > if switching from Minocycline to Zithromax will cause a flare? I

> > flared real bad when I tried to quit my Minocycline cold-turkey,

> > but I guess the theory is if I switch from one antibiotic to the

> > other I should be ok? Any thoughts?

> >

> > Adam

> >

> >

> >

[Guest guest]

> ...Do you (or anyone else on this board) know how long it'll take

> for the Zithromax to kick in? The derm told me since I'm switching

> from Minocycline to Zithromax (rather than starting from scratch)

> it shouldn't take as long...

As 007 says, blood levels will take about an hour after the first

(loading) dose, but what rosaceans need is " skin level " , which varies

from person to person but usually takes weeks -- and likewise, takes

weeks to drop to zero once an antibiotic is discontinued. So a person

stopping one antibiotic and starting another will experience

the " skin level " of the first dropping as the second one rises; if

both are effective and their pharmacokinetics are complementary,

theoretically there should be no difference. Unfortunately, those are

the two unknown variables. But that shouldn't prevent a switch if

medically indicated. It's curious to me that your new dermatologist

wants to make a change before the phototherapy is complete.

Physicians doesn't usually " change horses " in midstream unless

medically necessary.

> I'll be twenty in July, but I am sure I will still act like a

teenager

As does everyone, Adam. Happy birthday.

Marjorie

Marjorie Lazoff, MD

[Guest guest]

> ...Do you (or anyone else on this board) know how long it'll take

> for the Zithromax to kick in? The derm told me since I'm switching

> from Minocycline to Zithromax (rather than starting from scratch)

> it shouldn't take as long...

As 007 says, blood levels will take about an hour after the first

(loading) dose, but what rosaceans need is " skin level " , which varies

from person to person but usually takes weeks -- and likewise, takes

weeks to drop to zero once an antibiotic is discontinued. So a person

stopping one antibiotic and starting another will experience

the " skin level " of the first dropping as the second one rises; if

both are effective and their pharmacokinetics are complementary,

theoretically there should be no difference. Unfortunately, those are

the two unknown variables. But that shouldn't prevent a switch if

medically indicated. It's curious to me that your new dermatologist

wants to make a change before the phototherapy is complete.

Physicians doesn't usually " change horses " in midstream unless

medically necessary.

> I'll be twenty in July, but I am sure I will still act like a

teenager

As does everyone, Adam. Happy birthday.

Marjorie

Marjorie Lazoff, MD

[Guest guest]

> ...Do you (or anyone else on this board) know how long it'll take

> for the Zithromax to kick in? The derm told me since I'm switching

> from Minocycline to Zithromax (rather than starting from scratch)

> it shouldn't take as long...

As 007 says, blood levels will take about an hour after the first

(loading) dose, but what rosaceans need is " skin level " , which varies

from person to person but usually takes weeks -- and likewise, takes

weeks to drop to zero once an antibiotic is discontinued. So a person

stopping one antibiotic and starting another will experience

the " skin level " of the first dropping as the second one rises; if

both are effective and their pharmacokinetics are complementary,

theoretically there should be no difference. Unfortunately, those are

the two unknown variables. But that shouldn't prevent a switch if

medically indicated. It's curious to me that your new dermatologist

wants to make a change before the phototherapy is complete.

Physicians doesn't usually " change horses " in midstream unless

medically necessary.

> I'll be twenty in July, but I am sure I will still act like a

teenager

As does everyone, Adam. Happy birthday.

Marjorie

Marjorie Lazoff, MD