Research articles about SCD and D #1

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Research articles about SCD and D #1

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra\

ct&list_uids=5094255&query_hl=1

J Pediatr. 1971 Oct;79(4):612-7.

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The response of infants to carbohydrate oral loads after recovery from

diarrhea.

Lifshitz F, Coello- P, Contreras-Gutierrez ML.

PIP: A clinical study was carried out to assess the response of 46

infants to oral loads of carbohydrates after recovery from severe

diarrhea. The response was measured by the increases in blood reducing

sugars and by the variations in the stool pattern following

administration of oral carbohydrates. Disaccharide oral loads were used

in the test. During the acute stage of the illness, 38 of the 46

patients had exhibited intolerance to carbohydrates, as evidenced by the

excretion of acid stools and/or stools with a greater than .25%

carbohydrate content. Prompt improvement from diarrhea was induced by

elimination of all lactose, disaccharides, and other carbohydrates from

the diet. None of the infants had monosaccharide intolerance during the

acute diarrheal stage. The carbohydrate oral loads were administered

within 1 week after recovery and serially thereafter. Responses to

sucrose and lactose loads were related to the degree of intolerance

exhibited during the illness. In infants with diarrhea, the impaired

carbohydrate metabolism is temporary. Oral feedings may be administered

after cessation of profuse diarrhea and vomiting and after replacement

of water and electrolytes. Patients should be back on a milk formula

within 3-4 months, depending on the degree of carbohydrate intolerance

exhibited during the illness.

PMID: 5094255 [PubMed - indexed for MEDLINE]

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra\

ct&list_uids=3969931&query_hl=5

1: Am J Clin Nutr. 1985 Feb;41(2):228-34.

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Tolerance to glucose polymers in malnourished infants with diarrhea and

disaccharide intolerance.

Fagundes-Neto U, Viaro T, Lifshitz F.

The response of infants with diarrhea and lactose intolerance to

feedings containing soy protein and sucrose (Sobee), and/or to a

carbohydrate free formula (RCF), to which glucose polymers (GP) were

added, was assessed in twenty patients. They all were less than ten

months of age and had varying degrees of malnutrition. Eleven had acute

diarrhea and nine had chronic diarrhea. None of them had classical

enteropathogenic strains and parasites in the stools. All had lactose

intolerance when feedings were begun with cow's milk formula and some

also had sucrose intolerance when fed sucrose containing soy formulas.

They had persistent loose stools and excreted feces with an acid pH and

with carbohydrates, thus they were given dietary treatment with RCF with

GP. There were 9 patients with acute diarrhea and lactose intolerance (1

of them also had sucrose intolerance), who improved on RCF with GP

feedings; but 2 patients (lactose and sucrose intolerant) failed to

respond to this diet. There were six patients with chronic diarrhea and

lactose intolerance (four of them also had sucrose intolerance), who

improved on RCF with GP formula, but there were three patients who

failed on this treatment. These data show that some infants with

diarrhea, malnutrition, and lactose-sucrose intolerance may also develop

intolerance to GP and require further dietary management with glucose as

the source of carbohydrate in the diet.

PMID: 3969931 [PubMed - indexed for MEDLINE]

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