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Re: ANA Test

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Dana, there is a known association (not cause-effect or relationship,

just an association) between some immune mediated disorders and/or

some autoimmune disorders, and rosacea. There is also an association

between a positive ANA -- as you note, a laboratory test finding that

in isolation is not indicative of any disorder -- and all these

disorders.

There may well be something immunogenic involved in rosacea, although

the exact pathophysiology has not been worked out. Alternatively, it

may be that the genes that modulate rosacea are on the same

chromosome and close to the genes that control the immunologic

process involved in these disorders, so that the disorders " travel

together " as do the genes on the chromosomes, within the same person

or family.

As I've shared with the group before, my opinion is that something

more complicated is going on here, since we know rosacea appears much

more commonly in the fair and sensitive skinned, and that's not true

with these immune-mediated findings and disorders.

Marjorie

Marjorie Lazoff, MD

> > San, I have a high-positive ANA test result (every time I am

> tested, the

> > same number comes up) and I have rosacea and no other problems.

> However,

> > my daughter has Lupus and my grand daughter has Juvenile

Arthritis.

> The

> > doctors I've been to say it is autoimmune connected and

> > probably runs in the family and that nothing has triggered any

other

> > problems for me. I've been lucky. The doctors also like me to be

> checked

> > every year for potential kidney problems that could sneak up.

> >

> >

> >

> > ANA Test

> >

> >

> > > I'm new. A recent positive ANA test had me worried about

> lupus, but

> > > the Dr. says no. Went to see the Derm. and he diagonosed

rosacea.

> > > Is there any connection between the two? All other tests came

> back

> > > normal, no lupus, no RA. San

> > >

> > >

> > >

> > > --

> > > Please read the list highlights before posting to the whole

group

> > (http://rosacea.ii.net/toc.html). Your post will be delayed if

you

> don't

> > give a meaningful subject or trim your reply text. You must

change

> the

> > subject when replying to a digest !

> > >

> > > See http://www.drnase.com for info on his recently published

book.

> > >

> > > To leave the list send an email to

> > rosacea-support-unsubscribe@y...

> > >

> > >

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