Guest guest Posted May 6, 2002 Report Share Posted May 6, 2002 A while back, someone in the group described a rosacea-type reaction to a dental fluoride treatment, and asked if there was a known correlation. Here's an abstract that, although discussing an unrelated topic, definitely includes fluoride among a short list of known agents that aggrevate rosacea. JAAD is not freely available online, so I can't find out the primary source (the original research that demonstrates a link between fluoride and rosacea), but he says it enough times in this little abstract to make one believe HE believes it. J Am Acad Dermatol 2001 Jun;44(6):995-8 Related Articles, Books, LinkOut Tacrolimus ointment for the treatment of steroid-induced rosacea: a preliminary report. Goldman D. Department of Dermatology, NorthBay Healthcare Medical Group, Fairfield, CA 94533, USA. drdavidgoldman@... BACKGROUND: Excessive topical corticosteroid application to facial areas commonly leads to steroid-induced rosacea. This may be a recalcitrant problem that requires months of antibiotic and anti- inflammatory therapy before it resolves. OBJECTIVE: The purpose of this article is to review the use of tacrolimus ointment, a macrolide anti-inflammatory ointment for the treatment of 3 patients with steroid-induced rosacea. METHODS: Three patients with steroid-induced rosacea applied tacrolimus ointment, 0.075% twice daily for 7 to 10 days. Patients were also instructed to avoid topical corticosteroid use and other rosacea-aggravating substances including caffeine, spicy foods, alcohol, hot fluids, and fluoride. Patients were observed for tenderness, erythema, and relief of pruritus. RESULTS: Pruritus, tenderness, and erythema were resolved in all 3 patients after 7 to 10 consecutive days' use of tacrolimus 0.075% ointment in conjunction with avoidance of topical steroids, caffeine, spicy food, alcohol, hot fluids, and fluoride. CONCLUSION: This preliminary study demonstrates that tacrolimus 0.075% ointment may be effective for patients with steroid-induced rosacea, when combined with avoidance of topical steroid use, as well as avoidance of other agents known to aggravate rosacea (caffeine, spicy foods, alcohol, hot fluids, and fluoride). Marjorie Lazoff, MD Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2002 Report Share Posted May 6, 2002 It is widely believed that there is a correlation between perioral dermatitis and flouride, enough that non flourided toothpastes are recommended for those with perioral dermatitis. > > A while back, someone in the group described a rosacea-type reaction > to a dental fluoride treatment, and asked if there was a known > correlation. > > Here's an abstract that, although discussing an unrelated topic, > definitely includes fluoride among a short list of known agents that > aggrevate rosacea. JAAD is not freely available online, so I can't > find out the primary source (the original research that demonstrates > a link between fluoride and rosacea), but he says it enough times in > this little abstract to make one believe HE believes it. > > > J Am Acad Dermatol 2001 Jun;44(6):995-8 Related Articles, Books, > LinkOut > > > Tacrolimus ointment for the treatment of steroid-induced rosacea: a > preliminary report. > > Goldman D. > > Department of Dermatology, NorthBay Healthcare Medical Group, > Fairfield, CA 94533, USA. drdavidgoldman@m... > > BACKGROUND: Excessive topical corticosteroid application to facial > areas commonly leads to steroid-induced rosacea. This may be a > recalcitrant problem that requires months of antibiotic and anti- > inflammatory therapy before it resolves. OBJECTIVE: The purpose of > this article is to review the use of tacrolimus ointment, a macrolide > anti-inflammatory ointment for the treatment of 3 patients with > steroid-induced rosacea. METHODS: Three patients with steroid- induced > rosacea applied tacrolimus ointment, 0.075% twice daily for 7 to 10 > days. Patients were also instructed to avoid topical corticosteroid > use and other rosacea-aggravating substances including caffeine, > spicy foods, alcohol, hot fluids, and fluoride. Patients were > observed for tenderness, erythema, and relief of pruritus. RESULTS: > Pruritus, tenderness, and erythema were resolved in all 3 patients > after 7 to 10 consecutive days' use of tacrolimus 0.075% ointment in > conjunction with avoidance of topical steroids, caffeine, spicy food, > alcohol, hot fluids, and fluoride. CONCLUSION: This preliminary study > demonstrates that tacrolimus 0.075% ointment may be effective for > patients with steroid-induced rosacea, when combined with avoidance > of topical steroid use, as well as avoidance of other agents known to > aggravate rosacea (caffeine, spicy foods, alcohol, hot fluids, and > fluoride). > > Marjorie Lazoff, MD Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2002 Report Share Posted May 6, 2002 It is widely believed that there is a correlation between perioral dermatitis and flouride, enough that non flourided toothpastes are recommended for those with perioral dermatitis. > > A while back, someone in the group described a rosacea-type reaction > to a dental fluoride treatment, and asked if there was a known > correlation. > > Here's an abstract that, although discussing an unrelated topic, > definitely includes fluoride among a short list of known agents that > aggrevate rosacea. JAAD is not freely available online, so I can't > find out the primary source (the original research that demonstrates > a link between fluoride and rosacea), but he says it enough times in > this little abstract to make one believe HE believes it. > > > J Am Acad Dermatol 2001 Jun;44(6):995-8 Related Articles, Books, > LinkOut > > > Tacrolimus ointment for the treatment of steroid-induced rosacea: a > preliminary report. > > Goldman D. > > Department of Dermatology, NorthBay Healthcare Medical Group, > Fairfield, CA 94533, USA. drdavidgoldman@m... > > BACKGROUND: Excessive topical corticosteroid application to facial > areas commonly leads to steroid-induced rosacea. This may be a > recalcitrant problem that requires months of antibiotic and anti- > inflammatory therapy before it resolves. OBJECTIVE: The purpose of > this article is to review the use of tacrolimus ointment, a macrolide > anti-inflammatory ointment for the treatment of 3 patients with > steroid-induced rosacea. METHODS: Three patients with steroid- induced > rosacea applied tacrolimus ointment, 0.075% twice daily for 7 to 10 > days. Patients were also instructed to avoid topical corticosteroid > use and other rosacea-aggravating substances including caffeine, > spicy foods, alcohol, hot fluids, and fluoride. Patients were > observed for tenderness, erythema, and relief of pruritus. RESULTS: > Pruritus, tenderness, and erythema were resolved in all 3 patients > after 7 to 10 consecutive days' use of tacrolimus 0.075% ointment in > conjunction with avoidance of topical steroids, caffeine, spicy food, > alcohol, hot fluids, and fluoride. CONCLUSION: This preliminary study > demonstrates that tacrolimus 0.075% ointment may be effective for > patients with steroid-induced rosacea, when combined with avoidance > of topical steroid use, as well as avoidance of other agents known to > aggravate rosacea (caffeine, spicy foods, alcohol, hot fluids, and > fluoride). > > Marjorie Lazoff, MD Quote Link to comment Share on other sites More sharing options...
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