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Substance P

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Ok, while I'm on the subject of things that I don't really understand..

In Dr Nase's book, he talks about how Substance P may play an important role in

cea. He mentions a doctor who has had success in treating vascular cea

using the drug Zofran. When I first got this book months ago I went through all

the medicines listed in it with my dad and asked him which ones were safe to

take, and he told me Zofran was used for chemotherapy or cancer or something and

had alot of possible side effects. Anyway, Dr Nase mentions a selective

substance P blocker MK-869 " currently undergoing extensive testing in human

clinical trials " that " shows great promise " . Well, now apparantly the studies

have been done.

Well, in the following article I found, it talks about substance P's role in

pain perception. The article talks about MK-869 which has been tested, and

found to be a useful antidepressant and antianxiety medication. The article

mentions that MK-869 has a very low incidence of side effects. So, the way I

understand it (please Nobody misconstrue this as a fact)... MK-869 is a

pain-relieving, flush-reducing, antidepressant/anti-anxiety medication with

minimal side effects that no doctors anywhere are using to treat cea. Can

somebody please explain to me where exactly I got mixed up? This doesn't sound

right..

Here is the link:

http://www.hosppract.com/cc/1998/cc9812.htm

Adam

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