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RE: C ester vs. ester-c

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The group may be interested in this email I received from Chris

(jackogreen).

Buffered = esterified = fat soluble form of Vitamin C.

Marjorie Lazoff, MD

> Greetings,

>

> The confusion is on the placement of " ester " in the name. ester-c

> is a buffered form of vitamin c with metabolites. C ester is the

> formulation Perricone endorses, and it's also known as C palmitate

> (formulated with palm oil) It's fat soluble so can (theoretically)

> be absorbed by the skin cell membranes.

>

> > Esterification changes an acid molecule into a pH neutral

> > molecule, so esterification of l-ascorbic acid would be expected

> > to give a more stable solution with a longer shelf life, that is

> > less irritating to the skin -- which is good news. The big

> > question is whether skin cells can re-convert an estered form

> > back into its acid form, and in high enough concentrations to do

> > any good clinically.

>

> The controversy with C palmitate is whether it's " bioavailable "

> enough to supply an effective level of c acid at the cellular

> level. Perricone and others claim it is; many claim it is not. I

> take it orally with EFA; tried it topically but had a bad reaction.

> I don't know if that was the palmitate, though, or just the jojoba

> I mixed it in because I seem to be getting a bad reaction to all

> topicals these days. My low GI diet and oral supplements seem to

> keep skin under control generally, thankfully.

>

> Chris

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