Guest guest Posted May 1, 2002 Report Share Posted May 1, 2002 I searched the Web, this group, Medline, and online medical databases looking for information on Nicomide and its active ingredient, nicotinamide. Not much out there. Maybe people here can help me? (1) I know about the nicotinamide/tetracycline study for bullous pemphigus, but that has nothing to do with rosacea. Can anyone direct me to clinical studies on the anti-inflammatory effects on skin from oral nicotinamide? Is there a topical preparation that has been shown safe and effective? (2) Why take Nicomide and not just supplemental nicotinamide if one is already happy with the zinc and folate levels in one's multivitamin? (3) Nicotinamide = niacinamide, right? Are there side effects at doses below, say, 1 gram daily? [i know they aren't the same side effects (good or bad ones) from niacin/nicotinic acid.] (4) What's the dose equivalent of niacin? My multivitamin has 125 mg of niacin as niacinamide/nicotinic acid. Assuming a 50/50 mixture, what dose of nicotinamide is that? [barry Hunt peripherally addressed this in an old post, so if he knows anything more I'd appreciate the information.] I don't know about taking it, I'm just fact-finding at this point. I know enough to know that I can really hurt myself by loading my cells full of megadoses of a vitamin day after day, even if it's water soluable and even if there are no known short-term side effects. The body is such a complicated chemical factory, it has mechanisms for dealing with too much of a substance that can escape subtle detection until it's too late. But, from the little I've seen, its proposed mechanism of action is very interesting. Thanks. Marjorie Marjorie Lazoff, MD Quote Link to comment Share on other sites More sharing options...
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