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Subject: Any experience with desmopressin??

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Hi Han's:

Fred hasn't ever used this med, but this is what I found on it. I know someone on the list was on a Nasal Spray for this reason, but not if it was this one.

Take Care Vera

Desmopressin

(des moe press' in)

Brand name(s): Concentraid; DDAVP; Stimate

Contents of this page:

Why is this medication prescribed?

How should this medicine be used?

Other uses for this medicine

What special precautions should I follow?

What special dietary instructions should I follow?

What should I do if I forget a dose?

What side effects can this medication cause?

What storage conditions are needed for this medicine?

What other information should I know?

Why is this medication prescribed?Desmopressin is a chemical that is similar to a hormone found naturally in your body. It increases urine concentration and decreases urine production. Desmopressin is used to prevent and control excessive thirst, urination, and dehydration caused by injury, surgery, and certain medical conditions, allowing you to sleep through the night without awakening to urinate. It is also used to treat specific types of diabetes insipidus and conditions after head injury or pituitary surgery.This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.How should this medicine be used?Desmopressin comes in a liquid that is administered into the nose and as a nasal spray. It usually is used twice a day (every morning and evening). For bed wetting, it is used every evening at bedtime. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use desmopressin exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.Do not take the liquid by mouth. With the nasal liquid, you will receive a soft, flexible plastic tube with special markings for measuring the dose and instructions on how to measure and administer it. After drawing the dose into the tube, insert one end of the tube into your nose and the other end into your mouth. Blow on the tube to force the liquid high into your nose. Do not allow the liquid to run into your mouth. Follow the directions carefully; if you have difficulty using the drug or giving it to a child, ask your doctor or pharmacist for advice.To use the nasal spray, first clear your nasal passages by gently blowing your nose. Insert the sprayer into a nostril. Sniff as you squeeze the sprayer once. To prevent mucus from entering the sprayer, release your grip after you remove the sprayer from your nose. Gently sniff two or three more times.Other uses for this medicineDesmopressin nasal spray may be used to treat a condition called chronic autonomic failure (when the body is not able to control urine production).Talk to your doctor about the possible risks of using this drug for your condition.What special precautions should I follow?Before using desmopressin,

tell your doctor and pharmacist if you are allergic to desmopressin or any other drugs.

tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially carbamazepine (Tegretol), chlorpropamide (Diabinese), clofibrate (Atromid-S), demeclocycline (Declomycin), epinephrine, lithium, and vitamins.

tell your doctor if you have or have ever had heart disease, high blood pressure, coronary artery disease, nose or sinus problems or surgery, or cystic fibrosis.

tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using desmopressin, call your doctor.

you should know that this drug may make you drowsy. Do not drive a car or operate machinery until you know how this drug affects you.

remember that alcohol can add to the drowsiness caused by this drug. What special dietary instructions should I follow?Your doctor may tell you to limit your intake of fluids. Follow your doctor's directions. Drinking too much causes water retention (bloating and swelling of the feet, ankles, and lower legs).What should I do if I forget a dose?Use the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not use a double dose to make up for a missed one.What side effects can this medication cause?Although side effects from desmopressin are not common, they can occur. If you experience any of the following symptoms, call your doctor immediately:

upset stomach

headache

stuffy or runny nose

reddening of the skin

stomach cramps

pain in the external genital area (in women) What storage conditions are needed for this medicine?Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it in the refrigerator; do not freeze. The nasal bottle contains 25 or 50 doses. Throw away any medication after that. Do not put any leftover medication into another bottle. Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.What other information should I know?Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to desmopressin.If desmopressin loses its effectiveness (if urination increases or you wake up earlier than usual to urinate), call your doctor. Your dose may need to be changed.Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.Last Revised - 11/12/2001

Web site>>> MEDLINEplus Drug Information: Desmopressin

******************************************

Please, does any of you have experience with the drug desmopressin?

I would be very pleased if any of you who knows something about desmopressin, could give me some advice, and share your experience.

Desmopressin is sold in Denmark under the name of Minirin.

Unfortunately, I have to get up very often during the night, - and my neurologist has now adviced me to take Minirin 0,1 mg, in order for me to get more continuous hours of sleep during the night. It is not a large amount, but my legs have been quite swollen. And I am not certain I am getting the desired result.

Thank you so much for any comment

Hans in Denmark

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My Doctor prescribed the DDAVP

nasal spray about five years ago for my problems with incontinence. At the same time he also gave me a prescription

for Ditropan. This was before I

was diagnosed with Shy Drager Syndrome (SDS) or knew that I had problems with

orthostatic hypotension (OH).

After a few days I was feeling very sick every time I stood up. The Doctor advised me to stop taking

both medications until I started feeling better again. He said that it was the Ditropan that

was causing my problems and advised me to start back on the DDAVP spray. However, I was never able to use the

spray more than two nights in a row without it making me feel really bad, even

when I was not standing up.

I tried it again a month later with the same results. It did prevent incontinence

every night that I took it, but the side effects were unbearable. One time I managed to take it up to

four nights in a row because the doctor said it shouldn’t be causing these side

effects and that they might get better if I would continue taking it. But it just continued to get worse the

longer I tried to take it. When I

stopped taking it the last time, after trying it four nights in a row, I think

I must have had to urinate every fifteen minutes for two days.

I don’t know why I had such a bad

reaction to the DDVAP spray, because it obviously does not effect everyone this

way. I still use Ditropan occasionally

to treat a very uncomfortable feeling of urgency that the urologist described

as bladder spasms. I still haven’t found anything that helps my problem with incontinence. The more soundly I sleep, the wetter I

am when I wake up. My problems

with incontinence started as soon as I got my sleep apnea under control. Another example of the light at the end

of the tunnel turning out to be just another train headed my way.

Jim Parsons

Any

experience with desmopressin??

Hi Han's:

Fred hasn't ever used this med, but this is what I found on it. I know

someone on the list was on a Nasal Spray for this reason, but not if it

was this one.

Take Care Vera

Desmopressin

(des moe press' in)

Brand name(s): Concentraid; DDAVP; Stimate

Contents of this page:

Why is

this medication prescribed?

How should

this medicine be used?

Other

uses for this medicine

What

special precautions should I follow?

What

special dietary instructions should I follow?

What

should I do if I forget a dose?

What

side effects can this medication cause?

What

storage conditions are needed for this medicine?

What

other information should I know?

Why is this medication prescribed?Desmopressin is a chemical that is similar to

a hormone found naturally in your body. It increases urine concentration and

decreases urine production. Desmopressin is used to prevent and control

excessive thirst, urination, and dehydration caused by injury, surgery, and

certain medical conditions, allowing you to sleep through the night without

awakening to urinate. It is also used to treat specific types of diabetes

insipidus and conditions after head injury or pituitary surgery.This medication

is sometimes prescribed for other uses; ask your doctor or pharmacist for more

information.How should this medicine be used?Desmopressin comes in a liquid

that is administered into the nose and as a nasal spray. It usually is used

twice a day (every morning and evening). For bed wetting, it is used every

evening at bedtime. Follow the directions on your prescription label carefully,

and ask your doctor or pharmacist to explain any part you do not understand.

Use desmopressin exactly as directed. Do not use more or less of it or use it

more often than prescribed by your doctor.Do not take the liquid by mouth. With

the nasal liquid, you will receive a soft, flexible plastic tube with special

markings for measuring the dose and instructions on how to measure and

administer it. After drawing the dose into the tube, insert one end of the tube

into your nose and the other end into your mouth. Blow on the tube to force the

liquid high into your nose. Do not allow the liquid to run into your mouth.

Follow the directions carefully; if you have difficulty using the drug or

giving it to a child, ask your doctor or pharmacist for advice.To use the nasal

spray, first clear your nasal passages by gently blowing your nose. Insert the

sprayer into a nostril. Sniff as you squeeze the sprayer once. To prevent mucus

from entering the sprayer, release your grip after you remove the sprayer from

your nose. Gently sniff two or three more times.Other uses for this

medicineDesmopressin nasal spray may be used to treat a condition called

chronic autonomic failure (when the body is not able to control urine

production).Talk to your doctor about the possible risks of using this drug for

your condition.What special precautions should I follow?Before using

desmopressin,

tell your doctor and pharmacist if you are allergic to desmopressin or any

other drugs.

tell your doctor and pharmacist what prescription and nonprescription

medications you are taking, especially carbamazepine (Tegretol), chlorpropamide

(Diabinese), clofibrate (Atromid-S), demeclocycline (Declomycin), epinephrine,

lithium, and vitamins.

tell your doctor if you have or have ever had heart disease, high blood

pressure, coronary artery disease, nose or sinus problems or surgery, or cystic

fibrosis.

tell your doctor if you are pregnant, plan to become pregnant, or are

breast-feeding. If you become pregnant while using desmopressin, call your

doctor.

you should know that this drug may make you drowsy. Do not drive a car or

operate machinery until you know how this drug affects you.

remember that alcohol can add to the drowsiness caused by this drug. What

special dietary instructions should I follow?Your doctor may tell you to limit

your intake of fluids. Follow your doctor's directions. Drinking too much

causes water retention (bloating and swelling of the feet, ankles, and lower

legs).What should I do if I forget a dose?Use the missed dose as soon as you

remember it. However, if it is almost time for the next dose, skip the missed

dose and continue your regular dosing schedule. Do not use a double dose to

make up for a missed one.What side effects can this medication cause?Although

side effects from desmopressin are not common, they can occur. If you

experience any of the following symptoms, call your doctor immediately:

upset stomach

headache

stuffy or runny nose

reddening of the skin

stomach cramps

pain in the external genital area (in women) What storage conditions are needed

for this medicine?Keep this medication in the container it came in, tightly

closed, and out of reach of children. Store it in the refrigerator; do not

freeze. The nasal bottle contains 25 or 50 doses. Throw away any medication

after that. Do not put any leftover medication into another bottle. Throw away

any medication that is outdated or no longer needed. Talk to your pharmacist

about the proper disposal of your medication.What other information should I

know?Keep all appointments with your doctor and the laboratory. Your doctor

will order certain lab tests to check your response to desmopressin.If

desmopressin loses its effectiveness (if urination increases or you wake up

earlier than usual to urinate), call your doctor. Your dose may need to be

changed.Do not let anyone else use your medication. Ask your pharmacist any

questions you have about refilling your prescription.Last Revised - 11/12/2001

Web

site>>> MEDLINEplus

Drug Information: Desmopressin

******************************************

Please, does any of you have experience with the drug desmopressin?

I would be very pleased if any of you who knows something about desmopressin,

could give me some advice, and share your experience.

Desmopressin is sold in Denmark under the name of Minirin.

Unfortunately, I have to get up very often during the night, - and my

neurologist has now advised me to take Minirin 0,1 mg, in order for me to get

more continuous hours of sleep during the night. It is not a large

amount, but my legs have been quite swollen. And I am not certain I am getting

the desired result.

Thank you so much for any comment

Hans in Denmark

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