Guest guest Posted July 31, 2002 Report Share Posted July 31, 2002 Hi Folks, I've read somewhere on the internet, but also perhaps on the list about midodrine as being a substitute for florinef with regards to the OH. Florinef seems to retain fluid on places where women wants to be thin :-) Midodrine reacts directly on the vains to increase tension. Our neuro is reluctant to prescribe midodrine since he has no experience with it, nor the government is fully in favor for use of midodrine for this use. Does anyone has more experience with the use of midodrine? Groetjes, Timo Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 31, 2002 Report Share Posted July 31, 2002 Timo, Many people on the list use midodrine (also known as proamatine). It can be use along with florinef or instead of florinef. The two act differently: Florinef acts to increase blood volume, by retaining water in the bloodstream. This is why it causes some swelling. It must be used with salt and the patient must consume 2 liters of water a day for it to be effective. It can also deplete potassium, so frequent blood tests are necessary to be sure electrolyte level are proper. Florinef is long acting. Midodrine acts to constrict the blood vessels, thus to raise the blood pressure. It must not be taken within 4 hours of lying down because it can raise supine (lying down) blood pressure to dangerous levels. It is short acting, and generally begins to work within 30 - 60 minutes of taking it and wears off in about 4 hours. Here is the link to the Shire (manufacturer of Midodrine) website: http://www.shire.com/default.asp?wci=main Carol & Rob Lexington, MA Florinef versus midodrine Hi Folks, I've read somewhere on the internet, but also perhaps on the list about midodrine as being a substitute for florinef with regards to the OH. Florinef seems to retain fluid on places where women wants to be thin :-) Midodrine reacts directly on the vains to increase tension. Our neuro is reluctant to prescribe midodrine since he has no experience with it, nor the government is fully in favor for use of midodrine for this use. Does anyone has more experience with the use of midodrine? Groetjes, TimoIf you do not wish to belong to shydrager, you may unsubscribe by sending a blank email to shydrager-unsubscribe Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 31, 2002 Report Share Posted July 31, 2002 Hi Timo, My husband, Jim, was on both for quite a long time. Because they work differently, they are often prescribed together. Florinef is much shorter acting, and midodrine's(Proamatine) effects are long lasting. The neuro added the Proamatine to Jim's regimen when the florinef didn't seem to do enough any more or last long enough. He took the Proamatine am and pm, which helped to stabilize his bp overall, and the florinef was three or four times a day - but the last one around supper time so the bp wasn't too high by the time he went down for the night. Worked great for him. Hugs, Nan -----Original Message-----From: Timo & Anne Sent: Wednesday, July 31, 2002 12:21 PMTo: shydrager Subject: Florinef versus midodrine Hi Folks, I've read somewhere on the internet, but also perhaps on the list about midodrine as being a substitute for florinef with regards to the OH. Florinef seems to retain fluid on places where women wants to be thin :-) Midodrine reacts directly on the vains to increase tension. Our neuro is reluctant to prescribe midodrine since he has no experience with it, nor the government is fully in favor for use of midodrine for this use. Does anyone has more experience with the use of midodrine? Groetjes, TimoIf you do not wish to belong to shydrager, you may unsubscribe by sending a blank email to shydrager-unsubscribe Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 1, 2002 Report Share Posted August 1, 2002 Nan: I think it is the other way around. The Florinef has a very long half life and the Midodrine has a short one. I think you got then confused. Barbara Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.