Co enzyme Q10

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Subject: Co enzyme Q10

Date: Mon, 5 Aug 2002 20:19:09 -0400

X-Message-Number: 1

The following is from , President of Vitaline, Regarding

Vitaline Co-Enzyme Q-10

Families with PD can order the Vitaline CoQ10 formula used in the

University of California at San Diego-PD

study looking to see if Vitaline Co-Enzyme Q-10 slows the progression of

PD. Patients and families can contact

Vitaline's customer service department at 1-. Families can

also visit Vitaline's website

(www. vitalinecoq10.com) to learn more. You do not have to be a health

professional to order or visit the site.

The results of the University of California at San Diego -PD study

conducted by Dr. Cliff Shults will be published

in October, in the 'Archives of Neurology' (a medical/scientific journal

that is peer reviewed and well respected in the medical nd neurological

community). Until the study is published, Vitaline and everyone else

associated with the study are not allowed to discuss the results of the

study. However, the results were positive.

Vitaline CoQ-10 was designated an Orphan Drug for Huntington Disease

(another neuro-degenrative disease,

with a US patient pool of 30,000). This was based on the results of a

recent clinical trail which showed an approximately 20% reduction in the

progression of the disease.

There are concerns about the cost of the Vitaline CoQ-10 formula. It is

expensive. Vitaline is not in the business of

offering products directly to consumers-- except in this case. Vitaline

develops and sells pharmaceuticals and dietary supplements to health

professionals. However, vitaline is concerned that the results of the PD

study would result in PD patients seeking out other untested, potentially

not effective products. And this happens naturally, as manyproducts called

'CoQ-10' are on the market as dietary supplements.

There are differences between Vitaline CoQ-10 and other CoQ-10s on the

market:

Vitaline CoQ-10 is a proprietary, patent-pending formulation with Orphan

Drug status for neuro-degenerative disease, with proof of its safety and

efficacy. Other products lack such proof.

Vitaline CoQ-10 is produced in an FDA approved pharmaceutical

manufacturing facility. Other products are produced in food grade

manufacturing facilities.

Vitaline CoQ-10 may cost twice as much for a one month supply of some

other products, but Vitaline CoQ-10 uses the natural form of CoQ10

(substantially more expensive than the chemical form). The natural form is

much better absorped and has no impurities. The current pricing is, below

Vitaline's wholesale cost for a comparable retail offering-- but, this is

notbeing offered at retail, or to doctors, because it is not appropriate

outside the PD community.

Vitaline CoQ-10 has a patent-pending delivery mechanism proven to be

absorbed in brain tissue and brain mitochondria (mitochondria are the

power sources of each cell). Vitaline CoQ-10 is proven safe and tolerable

at high doses (up to 3000mg per day). The NIH and PD researchers are

progressing with the next stidu using Vitaline CoQ-10, not any other

CoQ-10.

Patients may save $100 per month using another product which contains

CoQ-10,but:

The other product may not produce material benefits as other products

containing CoQ-10 offer no proof of

absorption or efficacy. That may be $100 wasted.

The other products have not been tested for side-effects at the doses

recommended by PD researchers.

The other CoQ-10 products have not been evaluated in double-blind, placebo

controlled studies which

demonstrated safety of PD patients at 1200mg per day. Vitaline has shown

such safety.

Vitaline wants PD patients and families to choose Vitaline CoQ-10 because

of its efficacy and safety.

as well as its Orphan Drug status from the FDA. However, the decision

belongs to the patient and the medical

professionals treating him or her.

The role of Ubiquinone (Co-enzyme Q-10) inside the mitochondria (the power

source of each cell)

Ubiquinone (CoQ-10) is intimately involved in transfering energy from NADH

Complex I to Complex II

In PD ubiquinone is decreased in mitochondria.

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Subject: Co enzyme q10

Date: Mon, 5 Aug 2002 20:19:54 -0400

X-Message-Number: 2

http://www.parkinson.org/coq10vitaline.htm