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Re: Eyes /Methotrexate

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Becky, have you tried Methotrexate via injection? I too have

terrible stomach problems so I give myself an injection once a week

and bypass the GI system..just a sugestion for you. I wish doctors

would suggest this more often.

Ruth

In a message

dated 9/29/06 1:49:49 PM Pacific Daylight Time, macandtosh626@...

writes:

>

>

> Saw eye dr yesterday and he said sarcoid inflammation left eye

(for some reason only affects left) and placed me on prednisolone

eye drops every hour until better then couple of times per

day...also started me on Nevanac eye drops twice per day (is an

NSAID for the eye...never heard of it before). Right hand (mostly

thumb) hurting and heart doing some weird skips so upped my pred by

2.5 mg this morning (my local rheum has told me to do this if have a

flare).

>

>

> Becky, I know that initially it's important to use those pred

drops every hour, and then SLOWLY wean off them. If you go off too

quickly (from hourly drops to every 4hrs to every 8 hrs to 2x day,

etc) you should find you have better success at your eyes not

continuing to go back into flare.

> Just like oral pred-- the eye drops HAVE to be tapered also.

>

> As for the thumb pain-- uping the pred is ok-- but if you see

that your flare is more systemic (you have eyes and sarc arthritis

right now) so it is effecting more than one system- you really need

to add something other than the prednisone to get this under

control.

>

> Both Methotrexate and Plaquenil are good 'steroid' sparing

adjuncts that should be added one at a time. You will find that

with the MTX- alot more of the arthritic part will mellow out.

>

> Also, I can't stress enough the issues of hydration and sugar

control when we go into flare. Since all our body joints and

ligaments should be " floating " in synovial fluid-- any smallest

amount of dehydration causes acute pain.

>

> Do take care,

> Tracie

> NS Co-owner/moderator

>

>

>

>

> ---------------------------------

> All-new Yahoo! Mail - Fire up a more powerful email and get

things done faster.

>

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My son did the methotrexate injections for a while (for his Crohn's

Disease) and they are quite easy to do. I forget if you're one of the

former nurses on the site, but none of my immediate family are health

care workers at all and we had no trouble at all learning to do the

injections. It's just a subcutaneous injection rather than one that

needs to go into a vein.

It's so odd that doctors recommend different things. My son's doctor

*only* recommended the injections--thought that oral methotrexate was

far too dangerous for anyone to take!

We eventually had to give up the injections, switching to oral 6MP,

because just this small injection was causing 1-2 days of intense

neuropathic pain and my son was afraid of the pain becoming permanent

in his legs. But I think they're definitely worth a try! Best, Debby

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Debby,Thanks so much for your input. I'll ask my rheum when I see her about this. I am a nurse who misses my profession a lot. It's funny though how pain and problems can put things in a real perspective...now I just want to live and be with my family. Have had a very bad night and day today with left leg/foot pain that feels lik,e burning and even hurts to have clothes touch the areas. Took Vicodin and it has taken the edge off but this is the worst I've had to date. Also, leg and foot feel numb in spots and jerk uncontrollably...sounds like SFN. Got to get through this flare. B/c of the steroids I'm taking a total of over 200 units of insulin per day (5 separate shots). Seems like this disease has taken me over. I'm tired. Again, thanks for your reply.Best to all,Becky fDeborah Merritt wrote: My son did the methotrexate injections for a while (for his Crohn's Disease) and they are quite easy to do. I forget if you're one of the former nurses on the site, but none of my immediate family are health care workers at all and we had no trouble at all learning to do the injections. It's just a subcutaneous injection rather than one that needs to go into a vein. It's so odd that doctors recommend different things. My son's doctor *only* recommended the injections--thought that oral methotrexate was far too dangerous for anyone to take! We eventually had to give up the injections,

switching to oral 6MP, because just this small injection was causing 1-2 days of intense neuropathic pain and my son was afraid of the pain becoming permanent in his legs. But I think they're definitely worth a try! Best, Debby

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